ES8201992A1 - Procedure for obtaining tiazoles (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for obtaining tiazoles (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8201992A1 ES8201992A1 ES499110A ES499110A ES8201992A1 ES 8201992 A1 ES8201992 A1 ES 8201992A1 ES 499110 A ES499110 A ES 499110A ES 499110 A ES499110 A ES 499110A ES 8201992 A1 ES8201992 A1 ES 8201992A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- procedure
- obtaining
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 CARBOXYL Chemical class 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDURE FOR THE OBTAINING OF THIAZOLES, OF FORMULA (I) M IN WHICH R1 AND R3 ARE ARILO OR ARILO SUBSTITUTED RADICALS, AND R2 IS AN ALIPHATIC CHAIN WITH A CARBOXYL OR LOW MOLECULAR WEIGHT GROUP. THEY CONSIST OF THE REACTION OF AN A-HALOCETONE OF FORUMALA (II) WITH ARYLAMIDES OF FORMULA R3-CONH2, IN WHICH R1, R2 AND R3 HAVE THE SAME MEANING THAT IN FORMULA (I) AND X MAY BE CHLORINE, JOKE OR IODINE. THE REACTION IS CARRIED OUT IN AN ORGANIC SOLVENT, IN THE PRESENCE OF AN EXCESS OF 50 TO 100 PER 100 PENTASULFIDE OF PHOSPHORUS, AT A TEMPERATURE BETWEEN 80 AND 115C. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS AS ANTI-INFLAMMATORY AGENTS. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES499110A ES499110A0 (en) | 1981-02-04 | 1981-02-04 | PROCEDURE FOR OBTAINING THIAZOLES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES499110A ES499110A0 (en) | 1981-02-04 | 1981-02-04 | PROCEDURE FOR OBTAINING THIAZOLES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8201992A1 true ES8201992A1 (en) | 1982-02-01 |
| ES499110A0 ES499110A0 (en) | 1982-02-01 |
Family
ID=8481806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES499110A Granted ES499110A0 (en) | 1981-02-04 | 1981-02-04 | PROCEDURE FOR OBTAINING THIAZOLES |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES499110A0 (en) |
-
1981
- 1981-02-04 ES ES499110A patent/ES499110A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES499110A0 (en) | 1982-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970606 |