ES8206538A1 - Un procedimiento para preparar un dimero de vinca - Google Patents

Un procedimiento para preparar un dimero de vinca

Info

Publication number
ES8206538A1
ES8206538A1 ES500536A ES500536A ES8206538A1 ES 8206538 A1 ES8206538 A1 ES 8206538A1 ES 500536 A ES500536 A ES 500536A ES 500536 A ES500536 A ES 500536A ES 8206538 A1 ES8206538 A1 ES 8206538A1
Authority
ES
Spain
Prior art keywords
vlb
pharmaceutical formulation
vinca
reaction
vinca dimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES500536A
Other languages
English (en)
Spanish (es)
Other versions
ES500536A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES500536A0 publication Critical patent/ES500536A0/es
Publication of ES8206538A1 publication Critical patent/ES8206538A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES500536A 1980-03-20 1981-03-18 Un procedimiento para preparar un dimero de vinca Expired ES8206538A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/132,246 US4357334A (en) 1980-03-20 1980-03-20 Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms

Publications (2)

Publication Number Publication Date
ES500536A0 ES500536A0 (es) 1982-08-16
ES8206538A1 true ES8206538A1 (es) 1982-08-16

Family

ID=22453135

Family Applications (2)

Application Number Title Priority Date Filing Date
ES500536A Expired ES8206538A1 (es) 1980-03-20 1981-03-18 Un procedimiento para preparar un dimero de vinca
ES509581A Granted ES509581A0 (es) 1980-03-20 1982-02-12 Un procedimiento para la preparacion de un dimero de la vinca.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES509581A Granted ES509581A0 (es) 1980-03-20 1982-02-12 Un procedimiento para la preparacion de un dimero de la vinca.

Country Status (28)

Country Link
US (1) US4357334A (2)
EP (1) EP0036762B1 (2)
JP (1) JPS56145293A (2)
KR (1) KR840002146B1 (2)
AR (1) AR228863A1 (2)
AT (1) ATE9761T1 (2)
AU (1) AU539564B2 (2)
BG (1) BG36200A3 (2)
CA (1) CA1159055A (2)
DD (1) DD157558A5 (2)
DE (1) DE3166544D1 (2)
DK (1) DK124281A (2)
EG (1) EG15247A (2)
ES (2) ES8206538A1 (2)
FI (1) FI810856L (2)
GB (1) GB2072184B (2)
GR (1) GR73870B (2)
HU (1) HU185247B (2)
IE (1) IE51034B1 (2)
IL (1) IL62378A (2)
NZ (1) NZ196511A (2)
PH (1) PH16213A (2)
PL (1) PL230226A1 (2)
PT (1) PT72695B (2)
RO (2) RO82171A (2)
SU (2) SU1017172A3 (2)
YU (1) YU66281A (2)
ZA (1) ZA811733B (2)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE64396T1 (de) * 1983-04-29 1991-06-15 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (2) 1976-09-08 1982-07-07 Lilly Co Eli
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4160767A (en) * 1976-12-06 1979-07-10 Eli Lilly And Company Vinca alkaloid intermediates
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4191688A (en) * 1977-08-08 1980-03-04 Eli Lilly And Company Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Also Published As

Publication number Publication date
DE3166544D1 (en) 1984-11-15
GR73870B (2) 1984-05-09
ATE9761T1 (de) 1984-10-15
HU185247B (en) 1984-12-28
EP0036762B1 (en) 1984-10-10
PH16213A (en) 1983-08-05
FI810856A7 (fi) 1981-09-21
DK124281A (da) 1981-09-21
DD157558A5 (de) 1982-11-17
BG36200A3 (bg) 1984-09-14
IE51034B1 (en) 1986-09-17
CA1159055A (en) 1983-12-20
ES500536A0 (es) 1982-08-16
ES8302009A1 (es) 1982-12-16
PL230226A1 (2) 1982-03-15
IE810609L (en) 1981-09-20
EP0036762A3 (en) 1981-10-07
RO82171A (ro) 1983-07-07
GB2072184A (en) 1981-09-30
AU6858181A (en) 1981-09-24
IL62378A (en) 1984-03-30
JPS56145293A (en) 1981-11-11
AR228863A1 (es) 1983-04-29
ZA811733B (en) 1982-10-27
YU66281A (en) 1983-10-31
EP0036762A2 (en) 1981-09-30
PT72695B (en) 1982-03-24
SU1200851A3 (ru) 1985-12-23
PT72695A (en) 1981-04-01
SU1017172A3 (ru) 1983-05-07
KR830005248A (ko) 1983-08-03
EG15247A (en) 1986-03-31
GB2072184B (en) 1984-01-11
AU539564B2 (en) 1984-10-04
US4357334A (en) 1982-11-02
ES509581A0 (es) 1982-12-16
RO82171B (ro) 1983-06-30
FI810856L (fi) 1981-09-21
KR840002146B1 (ko) 1984-11-23
NZ196511A (en) 1983-09-30
RO85813A (ro) 1984-11-25
IL62378A0 (en) 1981-05-20
RO85813B (ro) 1984-11-30

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