ES8207143A1 - Procedimiento para la preparacion de derivados de piridina . - Google Patents

Procedimiento para la preparacion de derivados de piridina .

Info

Publication number
ES8207143A1
ES8207143A1 ES507775A ES507775A ES8207143A1 ES 8207143 A1 ES8207143 A1 ES 8207143A1 ES 507775 A ES507775 A ES 507775A ES 507775 A ES507775 A ES 507775A ES 8207143 A1 ES8207143 A1 ES 8207143A1
Authority
ES
Spain
Prior art keywords
tetrahydroquinolines
related compounds
cyano derivatives
treated
product obtained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507775A
Other languages
English (en)
Other versions
ES507775A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Publication of ES507775A0 publication Critical patent/ES507775A0/es
Publication of ES8207143A1 publication Critical patent/ES8207143A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE PIRIDINA. CONSISTE EN HACER REACCONAR UN COMPUESTO DE FOORMULA GENERAL (I) CON RARBNCN Y EL PRODUCTO OBTENIDO SE TRATA CONUN ORIGEN DE PROTON PARA OBTENER UN NITRILO DE FORMULA GENERAL (III). OPCIONALMENTE, EL PRODUCTO OBTENIDO SE TRATA CON UN AGENTE SULFURANTE,PARA OBTENER LA TIOAMIDA DE ORMULA GENERAL (II), DONDE X ES CSNHR; R1, R2, R3, R4 Y R5 S CON IGUALES O DIFERENTES Y REPRESENTAN RADICALES IDROGENO, ALQUILO, CICLOALQUILO, ARALQILO, O ARILO, PUDIENDO, CUALQUIERA DE DICHOS RADICALES SER SUSTITUIDO.
ES507775A 1980-12-09 1981-12-07 Procedimiento para la preparacion de derivados de piridina . Expired ES8207143A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8039423 1980-12-09

Publications (2)

Publication Number Publication Date
ES507775A0 ES507775A0 (es) 1982-09-01
ES8207143A1 true ES8207143A1 (es) 1982-09-01

Family

ID=10517861

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507775A Expired ES8207143A1 (es) 1980-12-09 1981-12-07 Procedimiento para la preparacion de derivados de piridina .

Country Status (15)

Country Link
US (1) US4529798A (es)
JP (1) JPS57131767A (es)
KR (1) KR830007572A (es)
AU (1) AU545972B2 (es)
CA (1) CA1138464A (es)
DK (1) DK542981A (es)
ES (1) ES8207143A1 (es)
FI (1) FI813940L (es)
GR (1) GR76932B (es)
HU (1) HU186446B (es)
IE (1) IE51857B1 (es)
NZ (1) NZ199122A (es)
PH (1) PH17891A (es)
PT (1) PT74093B (es)
ZA (1) ZA818302B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727149A (en) * 1982-03-11 1988-02-23 John Wyeth & Brother Limited Preparation of nitriles of fused ring pyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432378A (en) * 1972-10-21 1976-04-14 Wyeth John & Brother Ltd Fused carbocyclic ring derivatives of pyridine
US4160094A (en) * 1974-04-11 1979-07-03 John Wyeth & Brother Limited Tetrahydroquinoline derivatives
GB1465651A (en) * 1974-04-19 1977-02-23 Wyeth John & Brother Ltd Carbocyclic-fused ring pyridine derivatives

Also Published As

Publication number Publication date
GR76932B (es) 1984-09-04
PH17891A (en) 1985-01-21
IE51857B1 (en) 1987-04-15
PT74093A (en) 1982-01-01
NZ199122A (en) 1985-01-31
AU7823181A (en) 1982-06-17
AU545972B2 (en) 1985-08-08
PT74093B (en) 1983-05-23
CA1138464A (en) 1982-12-28
JPS57131767A (en) 1982-08-14
HU186446B (en) 1985-07-29
ES507775A0 (es) 1982-09-01
DK542981A (da) 1982-06-10
KR830007572A (ko) 1983-10-21
FI813940A7 (fi) 1982-06-10
IE812760L (en) 1982-06-09
US4529798A (en) 1985-07-16
ZA818302B (en) 1982-10-27
FI813940L (fi) 1982-06-10

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