ES8300111A1 - Procedimiento para la obtencion de derivados triciclicos de citosina. - Google Patents

Procedimiento para la obtencion de derivados triciclicos de citosina.

Info

Publication number
ES8300111A1
ES8300111A1 ES507807A ES507807A ES8300111A1 ES 8300111 A1 ES8300111 A1 ES 8300111A1 ES 507807 A ES507807 A ES 507807A ES 507807 A ES507807 A ES 507807A ES 8300111 A1 ES8300111 A1 ES 8300111A1
Authority
ES
Spain
Prior art keywords
wheel
attached
preparation
pharmaceutical preparations
cube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507807A
Other languages
English (en)
Other versions
ES507807A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8300111A1 publication Critical patent/ES8300111A1/es
Publication of ES507807A0 publication Critical patent/ES507807A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Lubricants (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Fats And Perfumes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

CONJUNTO DE TROLE PARA UN TRANSPORTADOR. CONSTA DE UNA MENSULA DE TROLE (12) QUE COMPRENDE UN EJE TUBULAR (14), UN CUBO ANULAR (16) FIJADO AL EJE TUBULAR (14) Y UNA RUEDA ANULA (18) MONTADA EN ROTACION EN UN CONJUNTO DE UN COJINETE DE BOLAS (20) INTERPUESTO ENTRE LA PERIFERIA EXTERIOR DEL CUBO (16) Y LA PERIFERIA INTERIOR DE LA RUEDA (18); DE UN PROTECTOR ANULAR (30) MONTADO EN EL EJE (14) Y SITUADO ENTRE LA MENSULA DEL TROLE (12) Y EL CUBO DE LA RUEDA (16); DE UN PRIMER OBTURADOR ANULAR (14) FIJADO A LA PERIFERIA INTERIOR DE LA RUEDA (18), QUE TIENE UNA PARTE EXTENDIDA RADIAL Y AXIALMENTE HACIA EL INTERIOR Y SEPARADA AXIALMENTE HACIA FUERA DEL PROTECTOR (30); Y DE UN SEGUNDO (46) Y TERCER (58) OBTURADORES ANULARE FIJADOS A LA RUEDA (18).
ES507807A 1980-12-09 1981-12-09 Procedimiento para la obtencion de derivados triciclicos de citosina. Granted ES507807A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803046366 DE3046366A1 (de) 1980-12-09 1980-12-09 Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES8300111A1 true ES8300111A1 (es) 1982-10-01
ES507807A0 ES507807A0 (es) 1982-10-01

Family

ID=6118700

Family Applications (2)

Application Number Title Priority Date Filing Date
ES507810A Expired ES8400076A1 (es) 1980-12-09 1981-12-09 Procedimiento para hidroformilar compuestos olefinicamente insaturados.
ES507807A Granted ES507807A0 (es) 1980-12-09 1981-12-09 Procedimiento para la obtencion de derivados triciclicos de citosina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES507810A Expired ES8400076A1 (es) 1980-12-09 1981-12-09 Procedimiento para hidroformilar compuestos olefinicamente insaturados.

Country Status (13)

Country Link
US (1) US4585772A (es)
EP (1) EP0053767B1 (es)
JP (1) JPS57122085A (es)
AT (1) ATE9350T1 (es)
AU (1) AU549240B2 (es)
CA (1) CA1184910A (es)
DE (2) DE3046366A1 (es)
DK (1) DK542781A (es)
ES (2) ES8400076A1 (es)
FI (1) FI813912A7 (es)
HU (1) HU191038B (es)
IL (1) IL64472A0 (es)
ZA (1) ZA818499B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4831013A (en) * 1986-03-20 1989-05-16 Ciba-Geigy Corporation 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines, pharmaceutical compositions, and uses thereof
FR2659329B1 (fr) * 1990-03-09 1994-06-03 Adir Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
US5212310A (en) * 1991-12-19 1993-05-18 Neurogen Corporation Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands
US5539260A (en) * 1994-08-29 1996-07-23 Ford Motor Company Method and apparatus for an automotive security system which permits engine running prior to code comparison
US5637929A (en) * 1996-01-16 1997-06-10 Ford Motor Company Method and apparatus for enhanced vehicle protection
BR0012984A (pt) * 1999-08-04 2002-07-16 Millennium Pharm Inc Método para tratar um estado associado com o mc4-r em um mamìfero, composto de ligação ao mc4-r, e, composição farmacêutica
US7375125B2 (en) * 1999-08-04 2008-05-20 Ore Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof
GB2453116B (en) * 2007-09-25 2010-03-17 Medical & Pharm Ind Tech & Dev Uses of 2-[piperidinyl]methy1-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one in providing an analgesic effect
WO2013177053A1 (en) * 2012-05-21 2013-11-28 Allergan, Inc. Pyrimidino [1, 2 -c] quinazolinone derivatives as tyrosine kinases inhibitors
CA2877146C (en) 2012-06-18 2020-10-20 Dart Neuroscience (Cayman) Ltd Substituted thiophene- and furan-fused azolopyrimidine-5-(6h)-one compounds
JP6420400B2 (ja) * 2017-04-12 2018-11-07 ダート・ニューロサイエンス・（ケイマン）・リミテッド 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物
CN108178759B (zh) * 2018-01-05 2020-06-09 上海瑞纷医药科技有限责任公司 一种α-肾上腺素受体拮抗剂的合成方法
GB2575490A (en) * 2018-07-12 2020-01-15 Recordati Ind Chimica E Farmaceutica Spa P2X3 receptor antagonists
EP4389746A3 (en) * 2022-12-21 2024-07-03 Recordati Industria Chimica E Farmaceutica SPA P2x3 receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3329679A (en) * 1965-12-22 1967-07-04 American Home Prod Fused-ring imidazoquinazolines, pyrimidoquinazolines and related compounds
US3594379A (en) * 1968-09-16 1971-07-20 Sandoz Ag 2,3-dihydroimidazo(1,2-c)quinazolines
CA986932A (en) * 1970-08-27 1976-04-06 Shigeho Inaba Process for preparing quinazoline derivatives
IE51802B1 (en) * 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US4585772A (en) 1986-04-29
JPS57122085A (en) 1982-07-29
FI813912L (fi) 1982-06-10
AU549240B2 (en) 1986-01-23
EP0053767B1 (de) 1984-09-12
HU191038B (en) 1986-12-28
IL64472A0 (en) 1982-03-31
DE3166084D1 (en) 1984-10-18
AU7831781A (en) 1982-06-17
EP0053767A1 (de) 1982-06-16
DK542781A (da) 1982-06-10
ES507810A0 (es) 1983-10-16
ES507807A0 (es) 1982-10-01
ES8400076A1 (es) 1983-10-16
ZA818499B (en) 1982-11-24
DE3046366A1 (de) 1982-07-08
ATE9350T1 (de) 1984-09-15
FI813912A7 (fi) 1982-06-10
CA1184910A (en) 1985-04-02

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