ES8300475A1 - Un procedimiento para la preparacion de un alergeno - Google Patents

Un procedimiento para la preparacion de un alergeno

Info

Publication number
ES8300475A1
ES8300475A1 ES501377A ES501377A ES8300475A1 ES 8300475 A1 ES8300475 A1 ES 8300475A1 ES 501377 A ES501377 A ES 501377A ES 501377 A ES501377 A ES 501377A ES 8300475 A1 ES8300475 A1 ES 8300475A1
Authority
ES
Spain
Prior art keywords
modified allergens
allergens
modified
allergies
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501377A
Other languages
English (en)
Other versions
ES501377A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8300475A1 publication Critical patent/ES8300475A1/es
Publication of ES501377A0 publication Critical patent/ES501377A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN ALERGENO ENLAZADO A UN OLIGOMERO. SE HACE REACCIONAR UN ALERGENO, TAL COMO UN EXTRACTO DE AMBROSIA O UNA MEZCLA DE HIERBAS, CON UN OLIGOMERO QUE CONSTA DE 1 A 5 AMINOACIDOS HIDROFOBICOS, TALES COMO FENILALANINA, VALINA, LEUCINA, ISOLEUCINA O NORLEUCINA, ESTANDO ENLAZADO EL OLIGOMERO AL ALERGENO A TRAVES DE UN PUENTE DE FORMULA (I) DONDE X ES UNA CADENA HIDROCARBONADA DE 1 A 4 CARBONOS QUE OPCIONALMENTE CONTIENE UN DOBLE ENLACE. >SE UTILIZA COMO AGENTE ACTIVO EN COMPOSICIONES TALES COMO VACUNAS.
ES501377A 1980-04-15 1981-04-14 Un procedimiento para la preparacion de un alergeno Granted ES501377A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8012295 1980-04-15

Publications (2)

Publication Number Publication Date
ES8300475A1 true ES8300475A1 (es) 1982-11-01
ES501377A0 ES501377A0 (es) 1982-11-01

Family

ID=10512783

Family Applications (1)

Application Number Title Priority Date Filing Date
ES501377A Granted ES501377A0 (es) 1980-04-15 1981-04-14 Un procedimiento para la preparacion de un alergeno

Country Status (8)

Country Link
EP (1) EP0038153A3 (es)
JP (1) JPS56161333A (es)
AU (1) AU6952281A (es)
CA (1) CA1175743A (es)
ES (1) ES501377A0 (es)
GR (1) GR74520B (es)
PT (1) PT72846B (es)
ZA (1) ZA812341B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0077158A1 (en) * 1981-10-09 1983-04-20 Beecham Group Plc Modified allergens
US5422258A (en) * 1987-12-31 1995-06-06 Tanox Biosystems, Inc. Methods for producing high affinity anti-human IgE-monoclonal antibodies which binds to IgE on IgEabearing B cells but not basophils
US5328991A (en) * 1989-11-03 1994-07-12 Immulogic Pharmaceutical Corp. Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1290141A (es) * 1968-05-31 1972-09-20
US4153684A (en) * 1976-03-10 1979-05-08 Agence Nationale De Valorisation De La Recherche (Anvar) Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
FR2437398A1 (fr) * 1978-06-20 1980-04-25 Commissariat Energie Atomique Compose iode utilisable comme traceur en radio-immunologie

Also Published As

Publication number Publication date
PT72846A (en) 1981-05-01
JPS56161333A (en) 1981-12-11
AU6952281A (en) 1981-10-22
ZA812341B (en) 1982-04-28
GR74520B (es) 1984-06-29
EP0038153A3 (en) 1982-12-22
CA1175743A (en) 1984-10-09
PT72846B (en) 1982-03-30
EP0038153A2 (en) 1981-10-21
ES501377A0 (es) 1982-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402