ES8300749A1 - Un procedimiento para la preparacion de piracin-carboxamidas - Google Patents

Un procedimiento para la preparacion de piracin-carboxamidas

Info

Publication number
ES8300749A1
ES8300749A1 ES81503566A ES503566A ES8300749A1 ES 8300749 A1 ES8300749 A1 ES 8300749A1 ES 81503566 A ES81503566 A ES 81503566A ES 503566 A ES503566 A ES 503566A ES 8300749 A1 ES8300749 A1 ES 8300749A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
halo
cycloalkyl
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES81503566A
Other languages
English (en)
Other versions
ES503566A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/165,313 external-priority patent/US4272537A/en
Priority claimed from US06/165,312 external-priority patent/US4277602A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES503566A0 publication Critical patent/ES503566A0/es
Publication of ES8300749A1 publication Critical patent/ES8300749A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE PIRAZINCARBOXAMIDAS Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE LA FORMULA (I), EN LA QUE R Y R SON HIDROGENO O ALCOHILO C <003> ; X ES HALOGENO Y R, R E Y PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE A UNA TEMPERATURA ENTRE 25<025>C Y EL PUNTO DE EBULLICION DEL DISOLVENTE. >ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DEL EDEMA Y DE LA HIPERTENSION.
ES81503566A 1980-07-02 1981-06-30 Un procedimiento para la preparacion de piracin-carboxamidas Expired ES8300749A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/165,313 US4272537A (en) 1980-07-02 1980-07-02 3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides
US06/165,312 US4277602A (en) 1980-07-02 1980-07-02 3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6-substituted-1,3,5-truazin-2-yl)2-pyrazinecarboxamides

Publications (2)

Publication Number Publication Date
ES503566A0 ES503566A0 (es) 1982-11-01
ES8300749A1 true ES8300749A1 (es) 1982-11-01

Family

ID=26861272

Family Applications (1)

Application Number Title Priority Date Filing Date
ES81503566A Expired ES8300749A1 (es) 1980-07-02 1981-06-30 Un procedimiento para la preparacion de piracin-carboxamidas

Country Status (6)

Country Link
EP (1) EP0043139B1 (es)
DE (1) DE3166701D1 (es)
DK (1) DK292181A (es)
ES (1) ES8300749A1 (es)
GR (1) GR74944B (es)
PT (1) PT73272B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804113B1 (fr) * 2000-01-26 2004-06-18 Lipha Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1256513A (es) * 1968-10-02 1971-12-08
US3549633A (en) * 1968-11-20 1970-12-22 Merck & Co Inc Process for preparation of 1-h-imidazo (4,5-b)pyrazin-2-ones
JPS5623425B2 (es) * 1973-11-09 1981-05-30
JPS52118483A (en) * 1976-03-29 1977-10-04 Nippon Shinyaku Co Ltd Nicotinylaminotriazine derivatives

Also Published As

Publication number Publication date
DK292181A (da) 1982-01-03
EP0043139B1 (en) 1984-10-17
PT73272B (en) 1983-05-11
GR74944B (es) 1984-07-12
PT73272A (en) 1981-07-01
EP0043139A1 (en) 1982-01-06
ES503566A0 (es) 1982-11-01
DE3166701D1 (en) 1984-11-22

Similar Documents

Publication Publication Date Title
ATE247654T1 (de) Neue heterozyklische verbindungen
EA200101194A1 (ru) Производные 4,5,6,7-тетрагидроиндазола в качестве противоопухолевых средств
TR200101893T2 (tr) Antiviral maddeler olarak 4-okso-1,4 dihidro -3- kuinolinkarboksamitler.
ATE116982T1 (de) 1-indolylalkyl-4-(substituierte pyridinyl)- piperazine.
ES470134A1 (es) Un procedimiento para la produccion de derivados sustituidosde ciclohexano-1,3-diona
YU26498A (sh) Derivati fenil- i aminofenil-alkilsulfonamida i uree
DE60232739D1 (de) Aktivator des peroxisomproliferator-aktivierten rezeptors delta
TR25360A (tr) HERBISID ÖZELLIKTE KARBOKSAMID TüREVLERI.
DE3750111D1 (de) Substituierte Phenyl-2-propensäure Derivate und ihre Verwendung als Fungizide.
EA200000614A1 (ru) 2,3-замещенные соединения индола в качестве ингибиторов сох-2
DK154092D0 (da) Imidazolforbindelser, deres fremstilling og anvendelse
ES2180201T3 (es) Derivados de azetidinona para el tratamiento de infecciones por hcmv.
ES8300749A1 (es) Un procedimiento para la preparacion de piracin-carboxamidas
DE3852008D1 (de) Verbindungen.
NO912963D0 (no) Farmasoeytiske forbindelser.
IL58321A (en) N-oxadiazolyl(thiadiazolyl)alkyl-halogenoacetanilides,their preparation and their use as herbicides
EA200400666A2 (ru) Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат
AU551411B2 (en) Diazolylalkanols useful as antimycotic agents
DK0478173T3 (da) 4,5-polymethylen-4-isothiazolin-3-onderivater og anvendelse heraf som biocider
TR199903249T2 (xx) �l-5 inhibit�rleri olarak 6-Azaurasil t�revleri.
DK553482A (da) Fremgangsmaade til fremstilling af n,n-disubstituerede alkenamider og phenylalkenamider
SE8101703L (sv) Nya isoxazolderivat jemte sett for deras framstellning
GB2005250A (en) (1-Alkylpyrrolyl-2)thio- acetamides
DE69112095D1 (de) 1-Phenoxycarbonyl-2-Pyrrolidon-Derivate und nootrope Wirkstoffe.
PT81422A (en) Process for the preparation of 3-amino-2,3-dihidro-1-benzoxepincompounds