ES8301475A1 - Procedimiento para la obtencion de un nuevo derivado de la tioformamida - Google Patents

Procedimiento para la obtencion de un nuevo derivado de la tioformamida

Info

Publication number
ES8301475A1
ES8301475A1 ES503727A ES503727A ES8301475A1 ES 8301475 A1 ES8301475 A1 ES 8301475A1 ES 503727 A ES503727 A ES 503727A ES 503727 A ES503727 A ES 503727A ES 8301475 A1 ES8301475 A1 ES 8301475A1
Authority
ES
Spain
Prior art keywords
pharmaceutical preparations
derivative
preparation
radical
preparations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES503727A
Other languages
English (en)
Other versions
ES503727A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Publication of ES8301475A1 publication Critical patent/ES8301475A1/es
Publication of ES503727A0 publication Critical patent/ES503727A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Lasers (AREA)
  • Instructional Devices (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Toys (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DE LA TIOFORMAMIDA, DE FORMULA GENERAL (I), EN LA QUE R REPRESENTA UN RADICAL ALQUILO; HET REPRESENTA UN RADICAL HETEROCICLICO DE CARACTER AROMATICO; X REPRESENTA UN ATOMO DE AZUFRE O DE OXIGENO, E Y REPRESENTA UN ATOMO DE AZUFRE O DE OXIGENO, UN ENLACE DE VALENCIA O UN RADICAL METILENO. CONSISTE EN HACER REACCIONAR UN DERIVADO DE FORMULA GENERAL (II), EN DONDE X, Y Y HET TIENEN LOS SIGNIFICADOS YA INDICADOS, CON UN DERIVADO ORGANO-LITICO Y A CONTINUACION CON UN ISOTIOCIANATO DE FORMULA: R''''''<024>N=C=S, EN LA QUE R'''''' REPRESENTA UN RADICAL ALQUILO. DE APLICACION EN PREPARADOS FARMACEUTICOS POR SU ACTIVIDAD ANTI-ULCERA Y ANTI-SECRETORA.
ES503727A 1980-08-18 1981-07-07 Procedimiento para la obtencion de un nuevo derivado de la tioformamida Granted ES503727A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8018035A FR2488609A1 (fr) 1980-08-18 1980-08-18 Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent

Publications (2)

Publication Number Publication Date
ES8301475A1 true ES8301475A1 (es) 1982-12-01
ES503727A0 ES503727A0 (es) 1982-12-01

Family

ID=9245232

Family Applications (2)

Application Number Title Priority Date Filing Date
ES501060A Expired ES8202819A1 (es) 1980-08-18 1981-04-03 Procedimiento para la obtencion de un nuevo derivado de la tioformamida
ES503727A Granted ES503727A0 (es) 1980-08-18 1981-07-07 Procedimiento para la obtencion de un nuevo derivado de la tioformamida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES501060A Expired ES8202819A1 (es) 1980-08-18 1981-04-03 Procedimiento para la obtencion de un nuevo derivado de la tioformamida

Country Status (24)

Country Link
US (1) US4379154A (es)
EP (2) EP0077083B1 (es)
JP (1) JPS5742687A (es)
KR (1) KR850001043B1 (es)
AT (1) ATE14730T1 (es)
CA (1) CA1161039A (es)
DE (1) DE3161861D1 (es)
DK (1) DK158735C (es)
ES (2) ES8202819A1 (es)
FI (1) FI810835L (es)
FR (1) FR2488609A1 (es)
GR (1) GR72767B (es)
HU (1) HU187325B (es)
IE (1) IE51263B1 (es)
IL (1) IL62380A (es)
MA (1) MA19106A1 (es)
NO (1) NO810962L (es)
NZ (1) NZ197071A (es)
OA (1) OA06767A (es)
PH (1) PH16520A (es)
PL (2) PL130530B1 (es)
PT (1) PT72718B (es)
SU (2) SU1093248A3 (es)
ZA (1) ZA813159B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511371A1 (fr) * 1981-08-11 1983-02-18 Rhone Poulenc Sante Nouveaux nitriles heterocycliques, leur preparation et leur utilisation pour la preparation de medicaments
FR2528849B1 (fr) * 1982-06-17 1985-06-21 Rhone Poulenc Sante Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
FR2573428B1 (fr) * 1984-11-20 1987-01-30 Rhone Poulenc Sante Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
GB8907306D0 (en) * 1989-03-31 1989-05-17 May & Baker Ltd New compositions of matter
FR2653770B1 (fr) * 1989-10-31 1992-01-03 Rhone Poulenc Sante Procede de preparation de (pyridyl-3)-2 tetrahydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r), les (pyridyl-3)-2 tetrhydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r) ainsi obtenus et les compositions pharmaceutiques qui les contiennent.
JPH04211048A (ja) * 1990-03-05 1992-08-03 Mitsubishi Kasei Corp チオカルバモイルアセトニトリル誘導体
HUT66229A (en) * 1991-10-14 1994-10-28 Eisai Co Ltd Thioformamide derivatives and process for producing them and pharmaceutical compositions containing them
US5625068A (en) * 1995-06-05 1997-04-29 American Cyanamid Company Substituted quinoline herbicide intermediates and process

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2100970B1 (es) * 1970-07-30 1975-08-01 Fujisawa Pharmaceutical Co
DK627174A (es) * 1974-01-17 1975-09-08 Ciba Geigy Ag
IE49570B1 (en) * 1979-03-30 1985-10-30 Rhone Poulenc Ind 2-(pyrid-2-yl)tetrahydrothiophene derivatives
FR2452488A1 (fr) * 1979-03-30 1980-10-24 Rhone Poulenc Ind Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent
JPS6134433A (ja) * 1984-08-31 1986-02-18 Nippon Telegr & Teleph Corp <Ntt> xy平面位置決め用アクチユエ−タ装置

Also Published As

Publication number Publication date
JPS5742687A (en) 1982-03-10
NZ197071A (en) 1983-07-15
EP0046417B1 (fr) 1984-01-11
PT72718B (fr) 1982-03-24
ATE14730T1 (de) 1985-08-15
PT72718A (fr) 1981-04-01
EP0046417A1 (fr) 1982-02-24
KR830006277A (ko) 1983-09-20
NO810962L (no) 1982-02-19
DK158735B (da) 1990-07-09
ZA813159B (en) 1983-07-27
PL130679B1 (en) 1984-08-31
EP0077083A1 (fr) 1983-04-20
CA1161039A (fr) 1984-01-24
KR850001043B1 (ko) 1985-07-19
IL62380A (en) 1984-11-30
IL62380A0 (en) 1981-05-20
ES501060A0 (es) 1982-02-01
HU187325B (en) 1985-12-28
DK130781A (da) 1982-02-19
PL130530B1 (en) 1984-08-31
SU1093248A3 (ru) 1984-05-15
JPH0259150B2 (es) 1990-12-11
IE51263B1 (en) 1986-11-26
GR72767B (es) 1983-12-02
FI810835A7 (fi) 1982-02-19
FR2488609A1 (fr) 1982-02-19
ES8202819A1 (es) 1982-02-01
MA19106A1 (fr) 1981-10-01
ES503727A0 (es) 1982-12-01
PL230552A1 (es) 1982-03-01
SU1209029A3 (ru) 1986-01-30
DK158735C (da) 1990-12-03
DE3161861D1 (en) 1984-02-16
IE811036L (en) 1982-02-18
US4379154A (en) 1983-04-05
FI810835L (fi) 1982-02-19
FR2488609B1 (es) 1984-05-04
EP0077083B1 (fr) 1985-08-07
PH16520A (en) 1983-11-10
OA06767A (fr) 1982-12-31

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