ES8301943A1 - "procedimiento de obtencion de un derivado de quinazolinona". - Google Patents
"procedimiento de obtencion de un derivado de quinazolinona".Info
- Publication number
- ES8301943A1 ES8301943A1 ES509087A ES509087A ES8301943A1 ES 8301943 A1 ES8301943 A1 ES 8301943A1 ES 509087 A ES509087 A ES 509087A ES 509087 A ES509087 A ES 509087A ES 8301943 A1 ES8301943 A1 ES 8301943A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- procedure
- obtaining
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- AVRPFRMDMNDIDH-UHFFFAOYSA-N 1h-quinazolin-2-one Chemical class C1=CC=CC2=NC(O)=NC=C21 AVRPFRMDMNDIDH-UHFFFAOYSA-N 0.000 title 1
- 238000005406 washing Methods 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000001816 cooling Methods 0.000 abstract 2
- 238000001035 drying Methods 0.000 abstract 2
- 238000001914 filtration Methods 0.000 abstract 2
- BSKHPKMHTQYZBB-UHFFFAOYSA-N 2-methylpyridine Chemical compound CC1=CC=CC=N1 BSKHPKMHTQYZBB-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- DXDBGSMRYVGPJM-UHFFFAOYSA-N azinous acid Chemical compound ON.ON DXDBGSMRYVGPJM-UHFFFAOYSA-N 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 238000010790 dilution Methods 0.000 abstract 1
- 239000012895 dilution Substances 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000021962 pH elevation Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- FAIAAWCVCHQXDN-UHFFFAOYSA-N phosphorus trichloride Chemical compound ClP(Cl)Cl FAIAAWCVCHQXDN-UHFFFAOYSA-N 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
- 238000006722 reduction reaction Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DE QUINAZOLINA DE FORMULA (I). CONSISTE EN LA REACCION DEL COMPUESTO DE FORMULA (II) CON EXCESO DE CLORHIDRATO DE HIDROXILAMINA EN PIRIDINA O UNA METILPIRIDINA, A REFLUJO, SEGUIDA DE ENFRIAMIENTO, FILTRACION, LAVADO Y SECADO; REACCION CON UN COMPUESTO DE FORMULA RCOCL, EN LA QUE R ES CLORO O ALCOXI, EN UN DISOLVENTE ORGANICO, SEGUIDA DE BASIFICACION, LAVADO Y SEPARACION, REDUCCION CON TRICLORURO DE FOSFORO, ENFRIAMIENTO, DILUCION CON AGUA, ALCALINIZACION, EXTRACCION, LAVADO, SECADO, FILTRACION Y EVAPORACION DEL DISOLVENTE. ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS COMO ANALGESICO Y ANTIINFLAMATORIO.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES509087A ES8301943A1 (es) | 1982-01-12 | 1982-01-12 | "procedimiento de obtencion de un derivado de quinazolinona". |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES509087A ES8301943A1 (es) | 1982-01-12 | 1982-01-12 | "procedimiento de obtencion de un derivado de quinazolinona". |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES509087A0 ES509087A0 (es) | 1983-01-01 |
| ES8301943A1 true ES8301943A1 (es) | 1983-01-01 |
Family
ID=8483565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509087A Expired ES8301943A1 (es) | 1982-01-12 | 1982-01-12 | "procedimiento de obtencion de un derivado de quinazolinona". |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8301943A1 (es) |
-
1982
- 1982-01-12 ES ES509087A patent/ES8301943A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES509087A0 (es) | 1983-01-01 |
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