ES8302648A1 - "procedimiento de preparacion de 2-oxo-1-pirrolidinilacetatos de 3,3,5-trimetilciclohexilo". - Google Patents
"procedimiento de preparacion de 2-oxo-1-pirrolidinilacetatos de 3,3,5-trimetilciclohexilo".Info
- Publication number
- ES8302648A1 ES8302648A1 ES510761A ES510761A ES8302648A1 ES 8302648 A1 ES8302648 A1 ES 8302648A1 ES 510761 A ES510761 A ES 510761A ES 510761 A ES510761 A ES 510761A ES 8302648 A1 ES8302648 A1 ES 8302648A1
- Authority
- ES
- Spain
- Prior art keywords
- oxo
- novel
- manufacture
- acetic acid
- acid ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JGPIWNNFLKDTSR-UHFFFAOYSA-N 2-(2-oxopyrrolidin-1-yl)acetic acid Chemical compound OC(=O)CN1CCCC1=O JGPIWNNFLKDTSR-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- -1 3,3,5-trimethyl-cyclohexyl Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 2-OXO-L-PIRROLIDINILACETATOS DE 3,3,5-TRIMETIL-CICLOHEXILO, DE FORMULA (I), EN LA QUE R Y R PUEDEN SER HIDROGENO, METILO O ETILO. CONSISTE EN LA REACCION DE UNA SAL DE METAL ALCALINO DE LA 2-PIRROLIDONA CON UN HALOACETATO DE 3,3,5-TRIMETILCICLOHEXILO DE FORMULA (II), EN LA QUE R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), Y X ES CLORO O BROMO. LA REACCION SE EFECTUA EN UN DISOLVENTE ORGANICO INERTE, A TEMPERATURAS ENTRE 50<025>C Y 110<025>C.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES510761A ES510761A0 (es) | 1982-03-24 | 1982-03-24 | "procedimiento de preparacion de 2-oxo-1-pirrolidinilacetatos de 3,3,5-trimetilciclohexilo". |
| DE8383400608T DE3371510D1 (en) | 1982-03-24 | 1983-03-23 | New 2-oxo-1-pyrrolidineacetic acid esters, their methods of production and therapeutic compositions containing the same |
| EP83400608A EP0089901B1 (en) | 1982-03-24 | 1983-03-23 | New 2-oxo-1-pyrrolidineacetic acid esters, their methods of production and therapeutic compositions containing the same |
| AT83400608T ATE27150T1 (de) | 1982-03-24 | 1983-03-23 | 2-oxo-1-pyrrolidinessigsaeureester, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die diese enthalten. |
| JP58049658A JPS58174359A (ja) | 1982-03-24 | 1983-03-24 | 新規な２−オキソ−１−ピロリジン酢酸エステルならびにその製造法および治療組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES510761A ES510761A0 (es) | 1982-03-24 | 1982-03-24 | "procedimiento de preparacion de 2-oxo-1-pirrolidinilacetatos de 3,3,5-trimetilciclohexilo". |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8302648A1 true ES8302648A1 (es) | 1983-02-01 |
| ES510761A0 ES510761A0 (es) | 1983-02-01 |
Family
ID=8483888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES510761A Granted ES510761A0 (es) | 1982-03-24 | 1982-03-24 | "procedimiento de preparacion de 2-oxo-1-pirrolidinilacetatos de 3,3,5-trimetilciclohexilo". |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS58174359A (es) |
| ES (1) | ES510761A0 (es) |
-
1982
- 1982-03-24 ES ES510761A patent/ES510761A0/es active Granted
-
1983
- 1983-03-24 JP JP58049658A patent/JPS58174359A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES510761A0 (es) | 1983-02-01 |
| JPS6260383B2 (es) | 1987-12-16 |
| JPS58174359A (ja) | 1983-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970612 |