ES8302721A1 - Un procedimiento para la preparacion de derivados de cefa- losporina - Google Patents

Un procedimiento para la preparacion de derivados de cefa- losporina

Info

Publication number
ES8302721A1
ES8302721A1 ES505718A ES505718A ES8302721A1 ES 8302721 A1 ES8302721 A1 ES 8302721A1 ES 505718 A ES505718 A ES 505718A ES 505718 A ES505718 A ES 505718A ES 8302721 A1 ES8302721 A1 ES 8302721A1
Authority
ES
Spain
Prior art keywords
derivatives
losporina
cefa
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES505718A
Other languages
English (en)
Other versions
ES505718A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8302721A1 publication Critical patent/ES8302721A1/es
Publication of ES505718A0 publication Critical patent/ES505718A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE CEFALOSPORINA, DE SUS SALES DE ADICION DE ACIDO Y DE HIDRATOS DE LOS ESTERES, DE FORMULA (I), EN LA QUE X ES UNO DE LOS GRUPOS DE FORMULA (II) O (III); Y R ES EL ALQUILO INFERIOR. CONSISTE EN LA REACCION DE ESTERIFICACION DE ACIDOS CARBOXILICOS DE FORMULA (I) O DE SUS SALES, POR TRATAMIENTO CON EL HALURO CORRESPONDIENTE, ESPECIALMENTE EL YODURO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE COMO ACELERADOR DE LA REACCION, A UNA TEMPERATURA COMPRENDIDA ENTRE 0<025>C Y 40<025>C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO Y PROFILAXIS DE ENFERMEDADES INFECCIOSAS.
ES505718A 1981-07-17 1981-09-23 Un procedimiento para la preparacion de derivados de cefa- losporina Granted ES505718A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28416081A 1981-07-17 1981-07-17
CH501881 1981-08-04

Publications (2)

Publication Number Publication Date
ES8302721A1 true ES8302721A1 (es) 1983-02-01
ES505718A0 ES505718A0 (es) 1983-02-01

Family

ID=25696765

Family Applications (1)

Application Number Title Priority Date Filing Date
ES505718A Granted ES505718A0 (es) 1981-07-17 1981-09-23 Un procedimiento para la preparacion de derivados de cefa- losporina

Country Status (31)

Country Link
EP (1) EP0070331A3 (es)
AT (1) AT375373B (es)
AU (1) AU7491481A (es)
BR (1) BR8106093A (es)
CA (1) CA1169853A (es)
CS (1) CS701481A2 (es)
CU (1) CU35528A (es)
DD (1) DD201683A5 (es)
DE (1) DE3134937A1 (es)
DK (1) DK379681A (es)
ES (1) ES505718A0 (es)
FI (1) FI812838L (es)
FR (1) FR2509733A1 (es)
GB (1) GB2101581B (es)
GR (1) GR75024B (es)
IL (1) IL63711A0 (es)
IN (1) IN155426B (es)
IT (1) IT1138195B (es)
MC (1) MC1420A1 (es)
NL (1) NL8104133A (es)
NO (1) NO812942L (es)
NZ (1) NZ198191A (es)
OA (1) OA06901A (es)
PH (1) PH17412A (es)
PL (1) PL131752B1 (es)
PT (1) PT73669B (es)
RO (1) RO82723B (es)
SE (1) SE8105628L (es)
SU (1) SU1140688A3 (es)
YU (1) YU217781A (es)
ZW (1) ZW22181A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115433137B (zh) * 2022-04-15 2025-03-07 内蒙古京科医药科技有限公司 1-甲基-1，2，4-三氮唑-3-甲醇的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT8067851A0 (it) * 1979-06-01 1980-05-30 Sankyo Co Derivati di cefalosporina sommini strabili per via orale e procedimento per la loro preparazione
CA1154009A (en) * 1980-03-25 1983-09-20 Roland Reiner Cephalosporin derivatives

Also Published As

Publication number Publication date
PL131752B1 (en) 1984-12-31
ZW22181A1 (en) 1983-02-09
PL233145A1 (en) 1983-02-14
MC1420A1 (fr) 1982-10-18
DK379681A (da) 1983-01-18
RO82723B (ro) 1984-02-28
SU1140688A3 (ru) 1985-02-15
IT1138195B (it) 1986-09-17
BR8106093A (pt) 1983-04-12
PH17412A (en) 1984-08-08
OA06901A (fr) 1983-04-30
DD201683A5 (de) 1983-08-03
GB2101581A (en) 1983-01-19
IT8123775A0 (it) 1981-09-03
CS701481A2 (en) 1984-02-13
ES505718A0 (es) 1983-02-01
EP0070331A2 (de) 1983-01-26
SE8105628L (sv) 1983-01-18
CU35528A (en) 1983-12-21
GR75024B (es) 1984-07-12
ATA371781A (de) 1983-12-15
GB2101581B (en) 1985-03-13
FI812838A7 (fi) 1983-01-18
FR2509733A1 (fr) 1983-01-21
NO812942L (no) 1983-01-18
PT73669A (en) 1981-10-01
IL63711A0 (en) 1981-12-31
IN155426B (es) 1985-01-26
NL8104133A (nl) 1983-02-16
CA1169853A (en) 1984-06-26
DE3134937A1 (de) 1983-01-27
NZ198191A (en) 1985-02-28
AU7491481A (en) 1983-01-20
AT375373B (de) 1984-07-25
PT73669B (en) 1983-10-20
EP0070331A3 (de) 1983-02-23
FI812838L (fi) 1983-01-18
YU217781A (en) 1983-12-31
RO82723A (ro) 1984-02-21

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