ES8303094A1 - "un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio". - Google Patents

"un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio".

Info

Publication number
ES8303094A1
ES8303094A1 ES509833A ES509833A ES8303094A1 ES 8303094 A1 ES8303094 A1 ES 8303094A1 ES 509833 A ES509833 A ES 509833A ES 509833 A ES509833 A ES 509833A ES 8303094 A1 ES8303094 A1 ES 8303094A1
Authority
ES
Spain
Prior art keywords
aqueous solution
cold insoluble
insoluble globulin
heat treatment
solution containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509833A
Other languages
English (en)
Other versions
ES509833A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Publication of ES509833A0 publication Critical patent/ES509833A0/es
Publication of ES8303094A1 publication Critical patent/ES8303094A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA INACTIVAR EL VIRUS DE LA HEPATITIS EN UNA GLOBULINA INSOLUBLE EN FRIO, MEDIANTE TRATAMIENTO TERMICO. CONSISTE EN CALENTAR ENTRE 50 A 80 C UNA DISOLUCION ACUOSA QUE CONTIENE GLOBULINA INSOLUBLE EN FRIO, DURANTE UN TIEMPO SUFICIENTE PARA DESACTIVAR EL VIRUS DE LA HEPATITIS, PERO CONSERVANDO LA ACTIVIDAD DE LA GLOBULINA, EN PRESENCIA DE 10% P/V DE AL MENOS UN ESTABILAZADOR TAL COMO AMINOACIDOS NEUTROS, MONOSACARIDOS, DISACARIDOS Y AZUCAR-ALCOHOLES. ESTA GLOBULINA TIENE APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTICANCEROSA Y ANTILEUCEMICA.
ES509833A 1981-02-25 1982-02-23 "un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio". Expired ES8303094A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56027448A JPS57140724A (en) 1981-02-25 1981-02-25 Heat-treatment of aqueous solution containing cold insoluble globulin

Publications (2)

Publication Number Publication Date
ES509833A0 ES509833A0 (es) 1983-02-01
ES8303094A1 true ES8303094A1 (es) 1983-02-01

Family

ID=12221394

Family Applications (1)

Application Number Title Priority Date Filing Date
ES509833A Expired ES8303094A1 (es) 1981-02-25 1982-02-23 "un procedimiento de tratamiento termico para inactivar el virus de hepatitis en una globulina insoluble en frio".

Country Status (6)

Country Link
US (1) US4424206A (es)
EP (1) EP0058993B1 (es)
JP (1) JPS57140724A (es)
AT (1) ATE52413T1 (es)
DE (1) DE3280166D1 (es)
ES (1) ES8303094A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2848529A1 (de) * 1978-11-09 1980-05-29 Behringwerke Ag Verfahren zur herstellung des kaelteunloeslichen globulins und dieses enthaltende arzneimittel
US4456590B2 (en) * 1981-11-02 1989-05-30 Heat treatment of lyphilized blood clotting factor viii concentrate
SE446688C (sv) * 1982-09-14 1989-10-16 Magnus Hoeoek Medel foer avlaegsnande av mikroorganismer fraan vaevnader, vilket bestaar av ett protein som kan bindas till mikroorganismerna
JPS5967228A (ja) * 1982-10-07 1984-04-16 Green Cross Corp:The 寒冷不溶性グロブリンの凍結乾燥方法
US4585654A (en) * 1983-04-29 1986-04-29 Armour Pharmaceutical Co. Process for pasteurizing fibronectin
DE3316464A1 (de) * 1983-05-05 1984-11-08 Heinrich Prof Dr Med Liehr Virusantigen, verfahren zu seiner gewinnung und anwendung in diagnose und therapie (impfstoff)
US4764369A (en) * 1983-07-14 1988-08-16 New York Blood Center Inc. Undenatured virus-free biologically active protein derivatives
US4820805A (en) * 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
US4615886A (en) * 1983-08-31 1986-10-07 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Utilizing a halohydrocarbon containing dissolved water to inactivate a lipid virus
JPS6094917A (ja) * 1983-10-28 1985-05-28 Green Cross Corp:The Ｂ型肝炎感染予防用ワクチンの製造方法
AT389815B (de) * 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
JPS61103836A (ja) * 1984-10-24 1986-05-22 Green Cross Corp:The フイブロネクチン製剤
AT385658B (de) * 1985-03-28 1988-05-10 Serotherapeutisches Inst Wien Verfahren zur herstellung einer fuer die anwendung beim menschen geeigneten fibronektinloesung
US4695454A (en) * 1985-04-01 1987-09-22 New York Blood Center, Inc. Process for preparing hepatitis B surface antigen containing particles in novel forms which are highly immunogenic
DE3619565A1 (de) * 1986-06-11 1987-12-17 Behringwerke Ag Verfahren zur herstellung einer pasteurisierten immunglobulinpraeparation
US5248767A (en) * 1986-06-11 1993-09-28 Behringwerke Aktiengesellschaft Process for the preparation of a pasteurized immunoglobulin preparation using ethanol
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
CA1310267C (en) * 1986-07-09 1992-11-17 Yutaka Hirao Process for heat treating chemically unmodified _-globulin
GB8628104D0 (en) * 1986-11-25 1986-12-31 Connaught Lab Pasteurization of immunoglobin solutions
CA2007545A1 (en) * 1989-01-13 1990-07-13 Yahiro Uemura Production method for protein-containing composition
USH1509H (en) * 1989-06-09 1995-12-05 Eran; Harutyun Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate
AU7494491A (en) * 1990-03-06 1991-10-10 Curative Technologies, Inc. Virus free platelet derivatives and method of making same
US5256771A (en) * 1990-04-03 1993-10-26 Miles Inc. Heat treatment of IgM-containing immunoglobulins to eliminate non-specific complement activation
JPH0565233A (ja) * 1991-03-08 1993-03-19 Mitsui Toatsu Chem Inc モノクローナル抗体含有凍結乾燥製剤
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
US5564345A (en) * 1993-05-11 1996-10-15 Park Ohio Industries Inc. Stackable table, table assembly, and tray and table combination
JP2948708B2 (ja) * 1991-11-27 1999-09-13 ニューヨーク・ブラッド・センター・インコーポレーテッド フィブロネクチン含有点眼液
DE69534187T2 (de) * 1994-05-13 2005-11-17 Miltenyi Biotec Gmbh Sterile und pyrogenfreie säulen, gekoppelt mit einem protein, zum binden und entfernen von substanzen aus dem blut
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
NL2009407C2 (en) * 2012-09-03 2014-03-04 Dutch Renewable Energy B V Antimicrobial composition.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL30448A (en) * 1967-08-02 1972-06-28 Diagnostic Data Inc Protein metal chelate composition stabilized with saccharide,and preparation thereof
JPS5322139B2 (es) * 1973-11-15 1978-07-06
JPS51118819A (en) * 1975-04-08 1976-10-19 Green Cross Corp:The A process for preparing heat stable antitrypsin
JPS51118820A (en) * 1975-04-08 1976-10-19 Green Cross Corp:The A process for preparing heat stable macroglobulin
JPS5359018A (en) * 1976-11-10 1978-05-27 Green Cross Corp:The Concentrated xiii-th blood coagulating factor derived from human placentaand its preparation
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
JPS56135418A (en) 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
US4305871A (en) 1980-09-02 1981-12-15 Edward Shanbrom Method of selectively increasing yield and purity of certain cryoprecipitate proteins by heating

Also Published As

Publication number Publication date
US4424206A (en) 1984-01-03
JPH0348169B2 (es) 1991-07-23
EP0058993A3 (en) 1985-01-23
JPS57140724A (en) 1982-08-31
ATE52413T1 (de) 1990-05-15
EP0058993A2 (en) 1982-09-01
ES509833A0 (es) 1983-02-01
DE3280166D1 (de) 1990-06-13
EP0058993B1 (en) 1990-05-09

Similar Documents

Publication Publication Date Title
EP0058993A3 (en) Process for heat treatment of aqueous solution containing cold insoluble globulin
DE3279807D1 (en) Process for heat treatment of aqueous solution containing human blood coagulation factor viii
KR860006478A (ko) γ－글로부린 수용액의 비루스－비활성화 열처리 방법
IN186258B (es)
DK369284D0 (da) Aprotininhomologe med andre aminosyrer i stilling 15 i stedet for lysin, fremgangsmaade til fremstilling heraf samt deres anvendelse som laegemiddel
HUT61477A (en) Virus inactivated blood product
US4650858A (en) Concentrate of the antihemophilic factor VIII and a process for producing it
GB8305128D0 (en) Process for recovering insulin
US4361652A (en) Method for stabilizing plasminogen
ES8400779A1 (es) Un metodo de mejorar la resistencia a la corrosion de un acero inoxidable sintetizado.
ES8308896A1 (es) "procedimiento para la eliminacion de los restos de catalizador a partir de poliolefinas".
JPS59134730A (ja) 血液凝固第８因子の加熱処理法
EP0292003B1 (en) Stabilzation of biological and pharmaceutical products during inactivation of viral and bacterial contaminants
CS570087A2 (en) Method of rhodium recovery
ES2006632A6 (es) Procedimiento de tratamiento termico de fibrinogeno.
AU8567091A (en) A method and composition for the protection of a metabolic recovery of ischemic cardiac tissue
RU96115481A (ru) Способ лечения деформирующего остеоартроза крупных суставов
EP0085220A3 (en) Method for purification of anterior pituitary hormones
GB1076776A (en) Process for the extraction of elastase
JPS6419023A (en) Heat treatment of fibrinogen and fibrinogen preparation
RO93391B (ro) Procedeu pentru prepararea unor saruri de dobutamina
IL83902A0 (en) Process for the preparation of 2,2-dibromonitrilopropionamide
AU7408787A (en) A process for the preparation of a pasteurized immunoglobulin preparation
ES360498A1 (es) Procedimiento de preparacion de monohidrato de lisina.
Hoffmann Measures for Ensuring the Welding Suitability of St 52-3

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401