ES8303461A1 - "procedimiento de preparacion de un soporte inerte de copolimero reticulado que contiene una sustancia farmaceuticamente activa susceptible de ser liberada progresivamente". - Google Patents
"procedimiento de preparacion de un soporte inerte de copolimero reticulado que contiene una sustancia farmaceuticamente activa susceptible de ser liberada progresivamente".Info
- Publication number
- ES8303461A1 ES8303461A1 ES509707A ES509707A ES8303461A1 ES 8303461 A1 ES8303461 A1 ES 8303461A1 ES 509707 A ES509707 A ES 509707A ES 509707 A ES509707 A ES 509707A ES 8303461 A1 ES8303461 A1 ES 8303461A1
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- support made
- inert support
- release drugs
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229920001577 copolymer Polymers 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000005250 alkyl acrylate group Chemical group 0.000 abstract 1
- 230000001588 bifunctional effect Effects 0.000 abstract 1
- 230000007246 mechanism Effects 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000010526 radical polymerization reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UN SOPORTE INERTE DE COPOLIMERO RETICULADO QUE CONTIENE UNA SUSTANCIA ACTIVA FISIOLOGICAMENTE, SUSCEPTIBLE DE SER LIBERADA PROGRESIVAMENTE. CONSISTE EN LA POLIMERIZACION POR RADICALES DE UNA MEZCLA DE MONOMEROS QUE CONSTA DE 30-80% DE UN ACRILATO Y/O UN METACRILATO DE ALCOHILO MONOINSATURADO, 5-68% DE ACIDO ACRILICO Y/O ACIDO METACRILICO Y 2-15% DE UN ESTER ACRILICO Y/O METACRILICO DI- O TRIFUNCIONAL; SEGUIDA DEL CONTACTO DEL COPOLIMERO OBTENIDO CON LA SUSTANCIA ACTIVA QUE ES ABSORBIDA EN EL MISMO. ESTOS COMPUESTOS TIENEN APLICACIONES PARA LA OBTENCION DE MEDICAMENTOS CON RETARDO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8014529A FR2485370A1 (fr) | 1980-06-30 | 1980-06-30 | Support inerte en copolymere reticule, son procede de preparation et son utilisation pour la realisation de medicaments retard |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8303461A1 true ES8303461A1 (es) | 1983-02-01 |
| ES509707A0 ES509707A0 (es) | 1983-02-01 |
Family
ID=9243677
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES503498A Granted ES503498A0 (es) | 1980-06-30 | 1981-06-29 | Procedimiento de preparacion de un soporte inerte de copoli-mero reticulado capaz de absorber y despues liberar progre- sivamente una sustancia farmaceuticamente activa |
| ES509707A Granted ES509707A0 (es) | 1980-06-30 | 1982-02-18 | "procedimiento de preparacion de un soporte inerte de copolimero reticulado que contiene una sustancia farmaceuticamente activa susceptible de ser liberada progresivamente". |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES503498A Granted ES503498A0 (es) | 1980-06-30 | 1981-06-29 | Procedimiento de preparacion de un soporte inerte de copoli-mero reticulado capaz de absorber y despues liberar progre- sivamente una sustancia farmaceuticamente activa |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US4590068A (es) |
| EP (1) | EP0043319B1 (es) |
| JP (1) | JPS5740416A (es) |
| AT (1) | ATE7200T1 (es) |
| CA (1) | CA1214596A (es) |
| DE (1) | DE3163290D1 (es) |
| ES (2) | ES503498A0 (es) |
| FR (1) | FR2485370A1 (es) |
| IE (1) | IE51336B1 (es) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2485370A1 (fr) * | 1980-06-30 | 1981-12-31 | Commissariat Energie Atomique | Support inerte en copolymere reticule, son procede de preparation et son utilisation pour la realisation de medicaments retard |
| US4608249A (en) * | 1982-11-02 | 1986-08-26 | Nitto Electric Industrial Co., Ltd. | Hydrophilic therapeutic material |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| JPS6263508A (ja) * | 1985-09-13 | 1987-03-20 | Kao Corp | 毛髪化粧料 |
| US5210166A (en) * | 1985-11-07 | 1993-05-11 | Basf Aktiengesellschaft | Copolymers of ethylene with polyalkylene glycol (meth)acrylates |
| US5955109A (en) * | 1985-12-18 | 1999-09-21 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of retinoic acid |
| US5879716A (en) * | 1985-12-18 | 1999-03-09 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of benzoyl peroxide |
| US5145675A (en) * | 1986-03-31 | 1992-09-08 | Advanced Polymer Systems, Inc. | Two step method for preparation of controlled release formulations |
| DE3789956T2 (de) * | 1986-08-15 | 1994-11-10 | Advanced Polymer Systems Inc | Polymere trägerzubereitungen, herstellung und verwendung. |
| US4830855A (en) * | 1987-11-13 | 1989-05-16 | Landec Labs, Inc. | Temperature-controlled active agent dispenser |
| ZA892859B (en) * | 1988-04-22 | 1989-12-27 | Advanced Polymer Systems Inc | Porous particles in preparations involving immiscible phases |
| FR2630326B1 (fr) * | 1988-04-25 | 1990-08-03 | Oreal | Composition cosmetique pour le maquillage contenant des microspheres de poly (beta)-alanine reticulee impregnees d'un alcool polyhydrique inferieur |
| ATE113841T1 (de) | 1989-10-31 | 1994-11-15 | Columbia Lab Inc | Mittel zur feuchthaltung vaginalen gewebes. |
| US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
| TW209174B (es) | 1991-04-19 | 1993-07-11 | Takeda Pharm Industry Co Ltd | |
| US5573934A (en) * | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
| US5389722A (en) * | 1992-06-05 | 1995-02-14 | Nippon Shokubai Co., Ltd. | Hydrophilic resin and method for production thereof |
| US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US5981719A (en) * | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US5516509A (en) * | 1993-03-31 | 1996-05-14 | International Beauty Design, Inc. | Quick-drying nail coating for use over nail polish |
| US5407666A (en) * | 1993-04-05 | 1995-04-18 | International Beauty Design, Inc. | Removable, hard, durable, nail coating |
| US5554147A (en) * | 1994-02-01 | 1996-09-10 | Caphco, Inc. | Compositions and devices for controlled release of active ingredients |
| US5788687A (en) | 1994-02-01 | 1998-08-04 | Caphco, Inc | Compositions and devices for controlled release of active ingredients |
| FR2737660B1 (fr) * | 1995-08-11 | 1997-09-12 | Oreal | Composition cosmetique a pouvoir fixant et/ou conditionneur contenant un copolymere acrylique particulier |
| EP0876412B1 (en) * | 1996-01-22 | 2005-04-27 | Ashland Inc. | Water-borne acrylic emulsion pressure-sensitive adhesive compositions containing multifunctional monomer having improved stability and removability |
| US5763555A (en) * | 1996-01-22 | 1998-06-09 | Ashland Inc. | Water-borne acrylic emulsion pressure-sensitive adhesive compositions containing multifunctional monomer having improved stability and removability |
| EP1545468A4 (en) * | 2002-09-20 | 2007-06-20 | Alpharma Inc | SUSTAINED RELEASE OPIOID PREPARATIONS AND METHODS OF USE |
| EP1656116A4 (en) * | 2003-08-22 | 2012-03-28 | Vista Scient Llc | POLYMER SYSTEMS FOR CONTROLLED MEDICINAL THERAPY |
| MX2009000890A (es) * | 2006-07-24 | 2009-02-05 | Amcol International Corp | Sistema de suministro y metodo de fabricacion del mismo. |
| ES2549000T3 (es) | 2009-07-27 | 2015-10-22 | Endologix, Inc. | Endoprótesis |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3080346A (en) * | 1958-11-15 | 1963-03-05 | Bayer Ag | Sustained-release pharmaceutical preparations |
| US3881026A (en) * | 1966-07-26 | 1975-04-29 | Nat Patent Dev Corp | Powdered water-insoluble polymers containing absorbed additives |
| US3608063A (en) * | 1969-08-15 | 1971-09-21 | Gilbert S Banker | Molecular drug entrapment process and compositions |
| US3857932A (en) * | 1970-09-09 | 1974-12-31 | F Gould | Dry hydrophilic acrylate or methacrylate polymer prolonged release drug implants |
| GB1394990A (en) * | 1971-08-12 | 1975-05-21 | Hydrophilics Int Inc | Copolymers and compositions containing copolymers |
| US3767790A (en) * | 1972-02-11 | 1973-10-23 | Nat Patent Dev Corp | Microorganisms |
| US3966902A (en) * | 1972-05-12 | 1976-06-29 | Airwick Industries, Inc. | Polymer complex carriers for an active ingredient |
| US3901967A (en) * | 1973-09-10 | 1975-08-26 | Union Corp | Sustained release of atropine |
| FR2250793B1 (es) * | 1973-11-09 | 1978-12-29 | Commissariat Energie Atomique | |
| CH602916A5 (es) * | 1975-09-10 | 1978-08-15 | Airwick Ag | |
| SE420101B (sv) * | 1978-03-03 | 1981-09-14 | Hoechst Perstorp Ab | Forfarande for framstellning av ett bindemedel for heftlim baserat pa en sampolymer av akrylestrar och eteniskt omettande syror |
| DE2908794C2 (de) * | 1978-03-09 | 1984-09-13 | Japan Atomic Energy Research Institute, Tokio/Tokyo | Verfahren zur Herstellung eines eine physiologisch aktive Substanz enthaltenden Polymerpräparates |
| FR2433949A1 (fr) * | 1978-08-25 | 1980-03-21 | Commissariat Energie Atomique | Substrat hydrophobe apte a liberer une substance chimique |
| FR2485370A1 (fr) * | 1980-06-30 | 1981-12-31 | Commissariat Energie Atomique | Support inerte en copolymere reticule, son procede de preparation et son utilisation pour la realisation de medicaments retard |
-
1980
- 1980-06-30 FR FR8014529A patent/FR2485370A1/fr active Granted
-
1981
- 1981-06-22 IE IE1390/81A patent/IE51336B1/en not_active IP Right Cessation
- 1981-06-25 EP EP81401023A patent/EP0043319B1/fr not_active Expired
- 1981-06-25 DE DE8181401023T patent/DE3163290D1/de not_active Expired
- 1981-06-25 AT AT81401023T patent/ATE7200T1/de not_active IP Right Cessation
- 1981-06-29 ES ES503498A patent/ES503498A0/es active Granted
- 1981-06-29 CA CA000380827A patent/CA1214596A/en not_active Expired
- 1981-06-30 JP JP56102208A patent/JPS5740416A/ja active Granted
-
1982
- 1982-02-18 ES ES509707A patent/ES509707A0/es active Granted
-
1983
- 1983-08-22 US US06/525,404 patent/US4590068A/en not_active Expired - Lifetime
-
1985
- 1985-08-07 US US06/763,253 patent/US4729904A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE7200T1 (de) | 1984-05-15 |
| ES8300471A1 (es) | 1982-11-01 |
| EP0043319A1 (fr) | 1982-01-06 |
| JPH0131490B2 (es) | 1989-06-26 |
| IE811390L (en) | 1981-12-30 |
| ES503498A0 (es) | 1982-11-01 |
| ES509707A0 (es) | 1983-02-01 |
| FR2485370A1 (fr) | 1981-12-31 |
| JPS5740416A (en) | 1982-03-06 |
| IE51336B1 (en) | 1986-12-10 |
| CA1214596A (en) | 1986-11-25 |
| US4729904A (en) | 1988-03-08 |
| FR2485370B1 (es) | 1984-01-06 |
| US4590068A (en) | 1986-05-20 |
| DE3163290D1 (en) | 1984-05-30 |
| EP0043319B1 (fr) | 1984-04-25 |
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