ES8303530A1 - Un procedimiento para la preparacion de un microorganismo que contiene un plasmido recombinante de un adn - Google Patents

Un procedimiento para la preparacion de un microorganismo que contiene un plasmido recombinante de un adn

Info

Publication number
ES8303530A1
ES8303530A1 ES507596A ES507596A ES8303530A1 ES 8303530 A1 ES8303530 A1 ES 8303530A1 ES 507596 A ES507596 A ES 507596A ES 507596 A ES507596 A ES 507596A ES 8303530 A1 ES8303530 A1 ES 8303530A1
Authority
ES
Spain
Prior art keywords
dna
recombinant plasmid
polypeptide
codes
double
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507596A
Other languages
English (en)
Other versions
ES507596A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japanese Foundation for Cancer Research
Original Assignee
Japanese Foundation for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13928979A external-priority patent/JPS5663996A/ja
Priority claimed from JP3393180A external-priority patent/JPS56131598A/ja
Application filed by Japanese Foundation for Cancer Research filed Critical Japanese Foundation for Cancer Research
Publication of ES507596A0 publication Critical patent/ES507596A0/es
Publication of ES8303530A1 publication Critical patent/ES8303530A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN MICROORGANISMO QUE CONTIENE UN PLASMIDO RECOMBINANTE DE UN ADN QUE PRESENTA COMPLEMENTARIEDAD CON EL ARN MENSAJERO DE INTERFERON HUMANO Y UN ADN RECTOR. CONSISTE EN TRANSFORMAR EL MICROORGANISMO ESCHERICHIA COLI X1776 CON EL PLASMIDO RECOMBINANTE T<PIF 319-13, CUYO ADN ESTA INSERTADO EN UN ADN RECTOR. LA TRANSFORMACION SE LLEVA A CABO SIGUIENDO METODOS CONVENCIONALES. ESTE MICROORGANISMO TIENE APLICACIONES CLINICAS POR SU ACTIVIDAD ANTIVIRAL Y ANTITUMORAL.
ES507596A 1979-10-30 1981-11-30 Un procedimiento para la preparacion de un microorganismo que contiene un plasmido recombinante de un adn Expired ES8303530A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13928979A JPS5663996A (en) 1979-10-30 1979-10-30 Novel recombinant having gene complementary to human interferon messenger rna
JP3393180A JPS56131598A (en) 1980-03-19 1980-03-19 Novel recombinant plasmid having gene of human fibroblastic interferon messenger rna

Publications (2)

Publication Number Publication Date
ES507596A0 ES507596A0 (es) 1983-02-01
ES8303530A1 true ES8303530A1 (es) 1983-02-01

Family

ID=26372701

Family Applications (3)

Application Number Title Priority Date Filing Date
ES496426A Expired ES8203102A1 (es) 1979-10-30 1980-10-30 Un procedimiento para la preparacion de un adn que codifica un polipeptido con actividad de interferon.
ES507595A Expired ES8303529A1 (es) 1979-10-30 1981-11-30 Un procedimiento para la produccion de un plasmido recombi- nante.
ES507596A Expired ES8303530A1 (es) 1979-10-30 1981-11-30 Un procedimiento para la preparacion de un microorganismo que contiene un plasmido recombinante de un adn

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES496426A Expired ES8203102A1 (es) 1979-10-30 1980-10-30 Un procedimiento para la preparacion de un adn que codifica un polipeptido con actividad de interferon.
ES507595A Expired ES8303529A1 (es) 1979-10-30 1981-11-30 Un procedimiento para la produccion de un plasmido recombi- nante.

Country Status (8)

Country Link
EP (1) EP0028033B1 (es)
AU (1) AU538665B2 (es)
CA (1) CA1341563C (es)
DE (1) DE3071435D1 (es)
DK (1) DK458480A (es)
ES (3) ES8203102A1 (es)
IL (1) IL61366A (es)
NO (1) NO158950C (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554513A (en) * 1979-11-21 1996-09-10 Yeda Research & Development Co. Ltd. Production of recombinant human interferon-beta2
US5510472A (en) * 1979-11-21 1996-04-23 Yeda Research And Development Co. Ltd. Production of recombinant human interferon-beta2
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
ES8308534A1 (es) * 1980-01-08 1983-09-01 Biogen Nv Un metodo de producir un polipeptido que exhibe actividad inmunologica o biologica del interferon de leucocitos humanos.
DK33181A (da) * 1980-02-06 1981-08-07 Searle & Co Fremgangsmaade til fremstilling af et interferonlignende protein
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
DE3005843A1 (de) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
EP0041313B1 (en) 1980-04-03 1990-09-12 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon
GR81946B (es) * 1980-09-25 1984-12-12 Genentech Inc
EP0062971B1 (en) * 1981-03-27 1990-03-07 Imperial Chemical Industries Plc Genetically modified microorganisms
IL65475A0 (en) * 1981-04-17 1982-07-30 Meloy Lab Production of immune interferon and its mrna
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
US4450103A (en) * 1982-03-01 1984-05-22 Cetus Corporation Process for recovering human IFN-β from a transformed microorganism
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
DE3220116A1 (de) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4855238A (en) 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
US5425940A (en) * 1986-04-09 1995-06-20 Cetus Oncology Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3751409T2 (de) 1986-04-15 1996-01-25 Ciba Geigy Ag Monoklonale Antikörper gegen Interferon-induziertes humanes Protein in gereignigter Form, und diese Antikörper enthaltende Testsätze.
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
GB9506051D0 (en) 1995-03-24 1995-05-10 Univ Singapore Gene expression
EP1426058A3 (de) 1997-09-23 2004-07-28 Dr. Rentschler Biotechnologie GmbH Flüssige Interferon-Beta Formulierungen
EP2213743A1 (en) 2000-04-12 2010-08-04 Human Genome Sciences, Inc. Albumin fusion proteins
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
AU2002364586A1 (en) 2001-12-21 2003-07-30 Delta Biotechnology Limited Albumin fusion proteins
WO2005003296A2 (en) 2003-01-22 2005-01-13 Human Genome Sciences, Inc. Albumin fusion proteins
SG161247A1 (en) 2005-04-11 2010-05-27 Savient Pharmaceuticals Inc Variant forms of urate oxidase and use thereof
JP5033177B2 (ja) 2006-04-12 2012-09-26 サビエント ファーマセウティカルズ インク． 陽イオン界面活性剤によるタンパク質の精製
EP2207890A4 (en) 2007-10-05 2010-12-15 Barofold Inc HIGH PRESSURE PROCESSING OF AGGREGATED INTERFERONS
US9377454B2 (en) 2009-06-25 2016-06-28 Crealta Pharmaceuticals Llc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta
CN116637177A (zh) 2016-11-11 2023-08-25 好利恩治疗美国公司 泼尼松和尿酸酶分子的组合疗法及其用途
WO2020160325A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Also Published As

Publication number Publication date
IL61366A (en) 1983-11-30
ES507595A0 (es) 1983-02-01
NO158950C (no) 1988-11-16
ES8303529A1 (es) 1983-02-01
CA1341563C (en) 2007-12-04
ES507596A0 (es) 1983-02-01
DE3071435D1 (en) 1986-03-27
EP0028033B1 (en) 1986-02-19
NO803230L (no) 1981-05-04
IL61366A0 (en) 1980-12-31
DK458480A (da) 1981-05-01
ES496426A0 (es) 1982-02-16
EP0028033A3 (en) 1981-08-19
AU538665B2 (en) 1984-08-23
NO158950B (no) 1988-08-08
ES8203102A1 (es) 1982-02-16
EP0028033A2 (en) 1981-05-06
AU6376280A (en) 1981-05-07

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