ES8304058A1 - Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10,14-hexadecapentaenoico. - Google Patents

Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10,14-hexadecapentaenoico.

Info

Publication number
ES8304058A1
ES8304058A1 ES509913A ES509913A ES8304058A1 ES 8304058 A1 ES8304058 A1 ES 8304058A1 ES 509913 A ES509913 A ES 509913A ES 509913 A ES509913 A ES 509913A ES 8304058 A1 ES8304058 A1 ES 8304058A1
Authority
ES
Spain
Prior art keywords
tetramethyl
hexadecapentaenoic acid
hexadecapentaenoic
acid
keratinisation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509913A
Other languages
English (en)
Other versions
ES509913A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4455880A external-priority patent/JPS56140949A/ja
Priority claimed from JP10442080A external-priority patent/JPS5731615A/ja
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES8304058A1 publication Critical patent/ES8304058A1/es
Publication of ES509913A0 publication Critical patent/ES509913A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DEL ACIDO 3,7,11,15-TETRAMETIL-2,4,6,10,14-HEXADECAPENTAENOICO Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (I) CON UN COMPUESTO DE FORMULA (II), EN LAS QUE Y ES ALQUILO INFERIOR O ARILO; X ES UN ATOMO DE HALOGENO Y R ES UN GRUPO ALQUILO INFERIOR; SEGUIDA DE LA REACCION DE DESULFINACION E HIDROLISIS EN PRESENCIA DE UNA BASE, A TEMPERATURA INFERIOR A LA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTICANCERIGENOS Y PARA EL TRATAMIENTO DE ENFERMEDADES DE LA PIEL.
ES509913A 1980-04-07 1982-02-25 Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10,14-hexadecapentaenoico. Granted ES509913A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4455880A JPS56140949A (en) 1980-04-07 1980-04-07 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid
JP10442080A JPS5731615A (en) 1980-07-31 1980-07-31 Remedy for skin disease with keratinization

Publications (2)

Publication Number Publication Date
ES8304058A1 true ES8304058A1 (es) 1983-02-16
ES509913A0 ES509913A0 (es) 1983-02-16

Family

ID=26384501

Family Applications (2)

Application Number Title Priority Date Filing Date
ES501124A Granted ES501124A0 (es) 1980-04-07 1981-04-06 Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10-14-hexadecapentaenoico.
ES509913A Granted ES509913A0 (es) 1980-04-07 1982-02-25 Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10,14-hexadecapentaenoico.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES501124A Granted ES501124A0 (es) 1980-04-07 1981-04-06 Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10-14-hexadecapentaenoico.

Country Status (11)

Country Link
AU (1) AU537402B2 (es)
CA (1) CA1179370A (es)
CH (1) CH646682A5 (es)
DE (1) DE3113149A1 (es)
DK (1) DK158457C (es)
ES (2) ES501124A0 (es)
FR (1) FR2479807A1 (es)
GB (1) GB2073750B (es)
IT (1) IT1194141B (es)
NL (1) NL191744C (es)
SE (1) SE447243B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56140949A (en) * 1980-04-07 1981-11-04 Eisai Co Ltd 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid
EP0059258B1 (en) * 1980-12-24 1984-05-30 Eisai Co., Ltd. Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases
JPS57106638A (en) * 1980-12-24 1982-07-02 Eisai Co Ltd Conjugated polyprenylcarboxylic acid and its derivative
JPS58164508A (ja) * 1982-03-26 1983-09-29 Eisai Co Ltd イソプレニルカルボン酸含有外用組成物
JPS5973516A (ja) * 1982-10-21 1984-04-25 Eisai Co Ltd 抗炎症剤
JPS6160612A (ja) * 1984-08-31 1986-03-28 Eisai Co Ltd 制癌効果増強剤
IL107587A (en) * 1993-11-12 1998-08-16 Univ Ramot Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation
CA2407421C (en) 2000-04-24 2009-11-03 Nikken Chemicals Co., Ltd. Activators of peroxisome proliferator-activated receptors
CN116041172B (zh) * 2023-02-01 2024-08-02 宝鸡文理学院 一种神经酸的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2171497A5 (en) * 1972-02-02 1973-09-21 Rhone Poulenc Sa 1,5-dimethyl-1,5-hexadienylidene sulphone derivs - - intermediates for terpenes
JPS52131507A (en) * 1976-04-24 1977-11-04 Sankyo Co Ltd Polyprenyl derivatives

Also Published As

Publication number Publication date
AU537402B2 (en) 1984-06-21
NL191744C (nl) 1996-06-04
DE3113149C2 (es) 1988-11-10
ES8205190A1 (es) 1982-06-01
GB2073750A (en) 1981-10-21
CH646682A5 (fr) 1984-12-14
AU6915981A (en) 1981-10-15
NL8101630A (nl) 1981-11-02
SE8102161L (sv) 1981-10-08
NL191744B (nl) 1996-02-01
FR2479807B1 (es) 1984-07-20
CA1179370A (en) 1984-12-11
IT1194141B (it) 1988-09-14
DK158457C (da) 1990-10-08
FR2479807A1 (fr) 1981-10-09
DE3113149A1 (de) 1982-01-28
SE447243B (sv) 1986-11-03
DK155081A (da) 1981-10-08
ES501124A0 (es) 1982-06-01
ES509913A0 (es) 1983-02-16
DK158457B (da) 1990-05-21
IT8120967A0 (it) 1981-04-07
GB2073750B (en) 1984-02-22

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