ES8304128A1 - "procedimiento de obtencion de 14,15-dihidro-14b-hidroxi (3x, 16x)-erbunamenina-14-carboxilico-metil ester.". - Google Patents
"procedimiento de obtencion de 14,15-dihidro-14b-hidroxi (3x, 16x)-erbunamenina-14-carboxilico-metil ester.".Info
- Publication number
- ES8304128A1 ES8304128A1 ES509074A ES509074A ES8304128A1 ES 8304128 A1 ES8304128 A1 ES 8304128A1 ES 509074 A ES509074 A ES 509074A ES 509074 A ES509074 A ES 509074A ES 8304128 A1 ES8304128 A1 ES 8304128A1
- Authority
- ES
- Spain
- Prior art keywords
- dihydro
- translation
- machine
- legally binding
- google translate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- JSLDLCGKZDUQSH-RTBUJCADSA-N 19-epivindolinine Natural products O=C(OC)[C@H]1[C@@]23[C@H](C)[C@]4([C@@H]5N(CC=C4)CC[C@]25c2c(N3)cccc2)C1 JSLDLCGKZDUQSH-RTBUJCADSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- KILNDJCLJBOWAN-UHFFFAOYSA-N Tabersonine Natural products CCC12CC(=C3N(C)c4cc(OC)ccc4C35CCN(CC=C1)C25)C(=O)OC KILNDJCLJBOWAN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000008447 perception Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- FNGGIPWAZSFKCN-ACRUOGEOSA-N tabersonine Chemical compound N1C2=CC=CC=C2[C@]2([C@H]34)C1=C(C(=O)OC)C[C@]3(CC)C=CCN4CC2 FNGGIPWAZSFKCN-ACRUOGEOSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- FNGGIPWAZSFKCN-UHFFFAOYSA-N xi-tabersonine Natural products N1C2=CC=CC=C2C2(C34)C1=C(C(=O)OC)CC3(CC)C=CCN4CC2 FNGGIPWAZSFKCN-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DEL ESTER METILICO DEL ACIDO 14,15-DIHIDRO-14~J-HIDROXI-(3~C,16~C)-ERBUNAMENINA-14-CARBOXILICO. CONSISTE EN LA HIDROGENACION DE ALCAOIDE TABERSONINA A PRESION ENTRE 100 MM HG Y 3 ATM, EN PRESENCIA DE CATALIZADOR DE PALADIO SOBRE CARBON DE 5%, EN MEDIO METANOLICO; SEGUIDA DE LA OXIDACION DE LA VINCADIFORMINA OBTENIDA, EN BECENO, CON UN PERACIDO ORGANICO; EXTRACCION DE LA DISOLUCION BENCENICA CON ACIDO ACETICO AL 60%, CON ACIDO ACETICO AL 10% Y CON AGUA; MEZCLA DE LOS EXTRACTOS; HIDROGENACION CATALITICA EN PRESENCIA DE PALADIO SOBRE CARBON; SEPARACION DEL CATALIZADOR POR FILTRACION; AJUSTE DEL PH A 9 Y EXTRACCION CON CLORURO DE METILENO. ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS PARA ESTABLECER Y MANTENER UN FLUJO SANGUINEO NORMAL.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES509074A ES8304128A1 (es) | 1982-01-26 | 1982-01-26 | "procedimiento de obtencion de 14,15-dihidro-14b-hidroxi (3x, 16x)-erbunamenina-14-carboxilico-metil ester.". |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES509074A ES8304128A1 (es) | 1982-01-26 | 1982-01-26 | "procedimiento de obtencion de 14,15-dihidro-14b-hidroxi (3x, 16x)-erbunamenina-14-carboxilico-metil ester.". |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES509074A0 ES509074A0 (es) | 1983-03-01 |
| ES8304128A1 true ES8304128A1 (es) | 1983-03-01 |
Family
ID=8483559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509074A Expired ES8304128A1 (es) | 1982-01-26 | 1982-01-26 | "procedimiento de obtencion de 14,15-dihidro-14b-hidroxi (3x, 16x)-erbunamenina-14-carboxilico-metil ester.". |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8304128A1 (es) |
-
1982
- 1982-01-26 ES ES509074A patent/ES8304128A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES509074A0 (es) | 1983-03-01 |
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