Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Sumitomo Pharma Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd, Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KKfiledCriticalDainippon Pharmaceutical Co Ltd
Priority to ES511376ApriorityCriticalpatent/ES511376A0/es
Publication of ES8304150A1publicationCriticalpatent/ES8304150A1/es
Publication of ES511376A0publicationCriticalpatent/ES511376A0/es
PROCEDIMIENTO PARA LA FABRICACION DE SUSTANCIAS PROTEINICAS FISIOLOGICAMENTE ACTIVAS, QUE TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTITUMORAL. CONSISTE EN PASAR UNA DISOLUCION CRUDA DE LA SUSTANCIA PROTEINICA DE PH 6,0 A 9,0 A TRAVES DE UN CAMBIADOR DE ANIONES BASICO; ELUIR LA SUSTANCIA FISIOLOGICAMENTE ACTIVA QUE HA SIDO ABSORBIDA; Y SOMETERLA A FILTRACION POR GEL, UTILIZANDO GELES PARA LA SEPARACION DE SUSTANCIAS DE PESO MOLECULAR ENTRE 30.000 Y 70.000, Y ELUYENDO CON UNA DISOLUCION DE PH ENTRE 6,0 Y 9,0.
ES511376A1982-04-131982-04-13"un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral".
GrantedES511376A0
(es)
N-acetylmuramyl-l-alanyl-d-isoglutamine stimulates the immune response of B cells: Use of fast protein liquid chromatography to purify a novel monokine involved in this effect