ES8304431A1 - "un metodo para preparar una inmunoglobulina adecuada para administracion intravenosa". - Google Patents

"un metodo para preparar una inmunoglobulina adecuada para administracion intravenosa".

Info

Publication number
ES8304431A1
ES8304431A1 ES512919A ES512919A ES8304431A1 ES 8304431 A1 ES8304431 A1 ES 8304431A1 ES 512919 A ES512919 A ES 512919A ES 512919 A ES512919 A ES 512919A ES 8304431 A1 ES8304431 A1 ES 8304431A1
Authority
ES
Spain
Prior art keywords
intravenous administration
preparing
immunoglobulin suitable
immunoglobulin
fractionation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512919A
Other languages
English (en)
Other versions
ES512919A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujizoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujizoki Pharmaceutical Co Ltd filed Critical Fujizoki Pharmaceutical Co Ltd
Publication of ES512919A0 publication Critical patent/ES512919A0/es
Publication of ES8304431A1 publication Critical patent/ES8304431A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE INMUNOGLOBULINA, QUE TIENE APLICACIONES FARMACOLOGICAS PARA ADMINISTRACION INTRAVENOSA. CONSISTE EN DISOLVER FRACCION II DE PLASMA DE COHN EN UNA DISOLUCION TAMPON DE FOSFATO DE PH 7,0 A 8,0, EN CONCENTRACION 2-3%, AÑADIR POLIETILENGLICOL DE PESO MOLECULAR 4.000 HASTA CONCENTRACION 3-4%; SEPARAR POR CENTRIFUGACION LOS AGREGADOS DE INMUNOGLOBULINA PRECIPITADOS; AÑADIR POLIETILENGLICOL 4.000 HASTA CONCENTRACION 6-8% A PH 6,5-7,0; Y SEPARAR LA INMUNOGLOBULINA EN FORMA DE PASTA.
ES512919A 1981-06-09 1982-06-08 "un metodo para preparar una inmunoglobulina adecuada para administracion intravenosa". Expired ES8304431A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56087503A JPS57203017A (en) 1981-06-09 1981-06-09 Purifying method of immunoglobulin

Publications (2)

Publication Number Publication Date
ES512919A0 ES512919A0 (es) 1983-03-01
ES8304431A1 true ES8304431A1 (es) 1983-03-01

Family

ID=13916779

Family Applications (1)

Application Number Title Priority Date Filing Date
ES512919A Expired ES8304431A1 (es) 1981-06-09 1982-06-08 "un metodo para preparar una inmunoglobulina adecuada para administracion intravenosa".

Country Status (4)

Country Link
US (1) US4379086A (es)
JP (1) JPS57203017A (es)
DE (1) DE3221448A1 (es)
ES (1) ES8304431A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58180433A (ja) * 1982-04-16 1983-10-21 Fujirebio Inc 免疫グロブリンから抗補体作用物質の除去法
US4719290A (en) * 1983-09-02 1988-01-12 Armour Pharmaceutical Corporation Composition of intravenous immune globulin
US4835257A (en) * 1984-07-07 1989-05-30 Armour Pharma Gmbh Process for preparing gamma globulin suitable for intravenous administration using peg and a citrate buffer
DE3483784D1 (de) * 1984-07-07 1991-01-31 Woelm Pharma Gmbh & Co Verfahren zur herstellung von gamma-globulin zur intravenoesen anwendung.
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
US5166322A (en) * 1989-04-21 1992-11-24 Genetics Institute Cysteine added variants of interleukin-3 and chemical modifications thereof
US5225325A (en) * 1990-03-02 1993-07-06 Ventana Medical Systems, Inc. Immunohistochemical staining method and reagents therefor
US5219578A (en) * 1991-02-25 1993-06-15 Innovet, Inc. Composition and method for immunostimulation in mammals
DE4344824C1 (de) * 1993-12-28 1995-08-31 Immuno Ag Hochkonzentriertes Immunglobulin-Präparat und Verfahren zu seiner Herstellung
US5695760A (en) * 1995-04-24 1997-12-09 Boehringer Inglehiem Pharmaceuticals, Inc. Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation
CN105026418B (zh) 2013-02-06 2019-01-11 新加坡科技研究局 蛋白质纯化方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL286954A (es) * 1962-01-03
DE2234069A1 (de) 1971-07-16 1973-02-08 South African Inventions Verfahren zur herstellung eines gereinigten gamma-globulins
US3763135A (en) * 1971-11-08 1973-10-02 Baxter Laboratories Inc Gamma globulin production from cohn fraction iii using polyethylene glycol
US3808189A (en) * 1973-03-15 1974-04-30 American Cyanamid Co Isolation of gamma globulin preparations enriched in iga and igm using polyethylene glycol
CA1064396A (en) * 1975-02-18 1979-10-16 Myer L. Coval Fractional precipitation of gamma globulin with polyethylene glycol
JPS6016406B2 (ja) * 1976-08-06 1985-04-25 マイヤ−、ル−イス、コ−バル 静脈内に投与可能なガンマ・グロブリンの製造法ならびにそれにより調製したガンマ・グロブリン
US4124576A (en) * 1976-12-03 1978-11-07 Coval M L Method of producing intravenously injectable gamma globulin
US4296027A (en) * 1977-08-31 1981-10-20 The Regents Of The University Of Minnesota Pure intravenous human and animal gamma globulins

Also Published As

Publication number Publication date
ES512919A0 (es) 1983-03-01
DE3221448C2 (es) 1988-12-08
DE3221448A1 (de) 1983-03-10
US4379086A (en) 1983-04-05
JPS57203017A (en) 1982-12-13

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