ES8304535A3 - A procedure for the preparation of halo-ter-butil-bencilaminas. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of halo-ter-butil-bencilaminas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8304535A3 ES8304535A3 ES508624A ES508624A ES8304535A3 ES 8304535 A3 ES8304535 A3 ES 8304535A3 ES 508624 A ES508624 A ES 508624A ES 508624 A ES508624 A ES 508624A ES 8304535 A3 ES8304535 A3 ES 8304535A3
- Authority
- ES
- Spain
- Prior art keywords
- bencilaminas
- butil
- ter
- halo
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 125000001246 bromo group Chemical group Br* 0.000 abstract 3
- 229910052740 iodine Chemical group 0.000 abstract 3
- 239000011630 iodine Chemical group 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- DXHPZXWIPWDXHJ-UHFFFAOYSA-N carbon monosulfide Chemical compound [S+]#[C-] DXHPZXWIPWDXHJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- 238000005658 halogenation reaction Methods 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 239000005555 hypertensive agent Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Process for the obtaining of halo-ter-butil-bencilaminas, of formula (I), in which r is halogen or methyl; and x is bromo or iodine. It consists in the reaction of halogenation of compounds of formula (II), in which they have the same meaning as in the formula (I), by treatment with bromo or monocloride of iodine. The reaction with bromo is effected in acetic acid or carbon sulfide as solvent, and with iodine monocloride is carried out in the presence of diluted hydrochloride acid. These compounds have pharmacological applications as diuretic and hypertensive agents. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES508624A ES8304535A3 (en) | 1982-01-11 | 1982-01-11 | A procedure for the preparation of halo-ter-butil-bencilaminas. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES508624A ES8304535A3 (en) | 1982-01-11 | 1982-01-11 | A procedure for the preparation of halo-ter-butil-bencilaminas. (Machine-translation by Google Translate, not legally binding) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES508624A0 ES508624A0 (en) | 1983-03-01 |
| ES8304535A3 true ES8304535A3 (en) | 1983-03-01 |
Family
ID=8483478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES508624A Expired ES8304535A3 (en) | 1982-01-11 | 1982-01-11 | A procedure for the preparation of halo-ter-butil-bencilaminas. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8304535A3 (en) |
-
1982
- 1982-01-11 ES ES508624A patent/ES8304535A3/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES508624A0 (en) | 1983-03-01 |
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