ES8304974A1 - "procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina". - Google Patents

"procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina".

Info

Publication number
ES8304974A1
ES8304974A1 ES513102A ES513102A ES8304974A1 ES 8304974 A1 ES8304974 A1 ES 8304974A1 ES 513102 A ES513102 A ES 513102A ES 513102 A ES513102 A ES 513102A ES 8304974 A1 ES8304974 A1 ES 8304974A1
Authority
ES
Spain
Prior art keywords
oxaciclil
alcohilpiperidina
derivatives
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513102A
Other languages
English (en)
Other versions
ES513102A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES513102A0 publication Critical patent/ES513102A0/es
Publication of ES8304974A1 publication Critical patent/ES8304974A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE N-OXACICLIL-ALCOHILPIPERIDINA, DE FORMULA GENERAL (I), EN LA QUE N SIGNIFICA 1, 2 O 3; P Y Q SIGNIFICAN 1, 2 O 3; PH SIFNIFICA 1,2-FENILENO NO SUSTITUIDO; R Y R SIGNIFICAN HIDROGENO O ALCOHILO; R Y R SIGNIFICAN HIDROGENO, FENILO O ALCOHILO; X SIGNIFICA OXIGENO O AZUFRE; E Y SIGNIFICA OXIGENO O AZUFRE, Y DE SUS SALES FISIOLOGICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), CON UN COMPUESTO DE FORMULA (III), EN LAS QUE P, Q, N, PH, R , R , R , R , R , X E Y TIENEN LOS SIGNIFICADOS YA INDICADOS; Y Z ES UN HALOGENO O UN GRUPO ESTER REACTIVO. DE APLICACION EN PREPARADOS FARMACEUTICOS POR SUS EFECTOS ANTIPSICOTICOS.
ES513102A 1981-06-20 1982-06-15 "procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina". Expired ES8304974A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813124366 DE3124366A1 (de) 1981-06-20 1981-06-20 N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung

Publications (2)

Publication Number Publication Date
ES513102A0 ES513102A0 (es) 1983-03-16
ES8304974A1 true ES8304974A1 (es) 1983-03-16

Family

ID=6135055

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513102A Expired ES8304974A1 (es) 1981-06-20 1982-06-15 "procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina".

Country Status (20)

Country Link
US (1) US4470989A (es)
EP (1) EP0068261B1 (es)
JP (1) JPS58977A (es)
KR (1) KR840000540A (es)
AT (1) ATE12498T1 (es)
AU (1) AU551182B2 (es)
CA (1) CA1175432A (es)
DE (2) DE3124366A1 (es)
DK (1) DK275782A (es)
ES (1) ES8304974A1 (es)
FI (1) FI822178L (es)
GR (1) GR76502B (es)
HU (1) HU190989B (es)
IE (1) IE53127B1 (es)
IL (1) IL66084A (es)
NO (1) NO822041L (es)
NZ (1) NZ201006A (es)
PH (1) PH18536A (es)
PT (1) PT75070B (es)
ZA (1) ZA824328B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3366460D1 (en) * 1982-08-05 1986-10-30 Toshiba Kk Color picture tube and method for manufacturing the same
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5221745A (en) * 1991-06-21 1993-06-22 American Home Products Corp. Psychotropic piperidinylmethyl benzodioxans
US5212170A (en) * 1991-06-21 1993-05-18 American Home Products Corporation Psychotropic piperidinylmethyl benzodioxans
US5182292A (en) * 1991-06-21 1993-01-26 American Home Products Corporation Psychotropic piperidinylmethyl benzodioxans
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
GB9603457D0 (es) * 1996-02-19 1996-04-17 Merck & Co Inc
US6096763A (en) * 1995-02-23 2000-08-01 Merck & Co., Inc. α1a adrenergic receptor antagonists
US5952351A (en) * 1995-02-23 1999-09-14 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
US6025355A (en) * 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
ATE256125T1 (de) 1999-06-02 2003-12-15 Janssen Pharmaceutica Nv Aminoalkyl substituierte (benzodioxane, benzofurane oder benzopyrane) derivate
JP2003501428A (ja) * 1999-06-02 2003-01-14 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ピロリジニル、ピペリジニルもしくはホモピペリジニル置換（ベンゾジオキサン、ベンゾフランもしくはベンゾピラン）誘導体
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) * 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
EP1451173A4 (en) * 2001-11-01 2005-10-26 Icagen Inc PIPERIDINE
EP1937670A1 (en) 2005-09-30 2008-07-02 Glaxo Group Limited Benzimidazolones which have activity at m1 receptor
ES2391107T3 (es) 2005-09-30 2012-11-21 Glaxo Group Limited Compuestos que tienen actividad en el receptor M1 y sus usos en medicina
EP1943230B1 (en) 2005-09-30 2010-12-22 Glaxo Group Limited Compounds which have activity at m1 receptor and their uses in medicine
GB0605784D0 (en) * 2006-03-22 2006-05-03 Glaxo Group Ltd Compounds
WO2009037294A1 (en) 2007-09-20 2009-03-26 Glaxo Group Limited Compounds which have activity at m1 receptor and their uses in medicine
GB0718415D0 (en) 2007-09-20 2007-10-31 Glaxo Group Ltd Compounds
CN108358832A (zh) * 2017-12-29 2018-08-03 上海艾康睿医药科技有限公司 一种合成4-[(2-氨基-4-氯)苯基]-氨基-n-哌啶甲酸乙酯的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US4066772A (en) * 1975-07-21 1978-01-03 Janssen Pharmaceutica N.V. 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
GR71865B (es) * 1978-03-20 1983-07-07 Ciba Geigy
US4181802A (en) * 1978-05-11 1980-01-01 Janssen Pharmaceutica N.V. 1-(Heterocyclylalkyl)-1,3-dihydro-2-H-benzimidazole-2-ones
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants

Also Published As

Publication number Publication date
CA1175432A (en) 1984-10-02
AU8499282A (en) 1983-01-06
FI822178A7 (fi) 1982-12-21
PT75070A (de) 1982-07-01
EP0068261A1 (de) 1983-01-05
IE821448L (en) 1982-12-20
HU190989B (en) 1986-12-28
DE3262861D1 (en) 1985-05-09
ZA824328B (en) 1983-04-27
NO822041L (no) 1982-12-21
PH18536A (en) 1985-08-09
JPS58977A (ja) 1983-01-06
DK275782A (da) 1982-12-21
KR840000540A (ko) 1984-02-25
PT75070B (de) 1985-01-07
IL66084A (en) 1986-07-31
IL66084A0 (en) 1982-09-30
NZ201006A (en) 1985-12-13
AU551182B2 (en) 1986-04-17
ES513102A0 (es) 1983-03-16
DE3124366A1 (de) 1982-12-30
EP0068261B1 (de) 1985-04-03
GR76502B (es) 1984-08-10
ATE12498T1 (de) 1985-04-15
FI822178A0 (fi) 1982-06-17
FI822178L (fi) 1982-12-21
IE53127B1 (en) 1988-07-06
US4470989A (en) 1984-09-11

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