ES8305703A1 - Un derivado de 2-benzoilamino-bencilamina. - Google Patents

Un derivado de 2-benzoilamino-bencilamina.

Info

Publication number
ES8305703A1
ES8305703A1 ES510608A ES510608A ES8305703A1 ES 8305703 A1 ES8305703 A1 ES 8305703A1 ES 510608 A ES510608 A ES 510608A ES 510608 A ES510608 A ES 510608A ES 8305703 A1 ES8305703 A1 ES 8305703A1
Authority
ES
Spain
Prior art keywords
formula
preparation
benzylamine derivative
substituted benzylamine
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510608A
Other languages
English (en)
Other versions
ES510608A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3870681A external-priority patent/JPS57154154A/ja
Priority claimed from JP14774681A external-priority patent/JPS5852261A/ja
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Publication of ES8305703A1 publication Critical patent/ES8305703A1/es
Publication of ES510608A0 publication Critical patent/ES510608A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 2-BENZOILAMINO-BENCILAMINA Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R ES HIDROGENO O HIDROXILO. CONSISTE EN LA REACCION DE HIDROLISIS, EN UN MEDIO ACUOSO DE UN ESTER DE FORMULA (II), EN LA QUE R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y R ES UN ALQUILO INFERIOR O ALCOXI INFERIOR. LA REACCION SE LLEVA A CABO A TEMPERATURAS ENTRE 0 C Y 100 C, A LA PRESION NORMAL. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ESPECTORANTE.
ES510608A 1981-03-19 1982-03-18 Un derivado de 2-benzoilamino-bencilamina. Granted ES510608A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3870681A JPS57154154A (en) 1981-03-19 1981-03-19 2-benzoylamino-substituted benzylamine derivative
JP14774681A JPS5852261A (ja) 1981-09-21 1981-09-21 ２−ベンゾイルアミノ置換ベンジルアミン誘導体およびその製造方法

Publications (2)

Publication Number Publication Date
ES8305703A1 true ES8305703A1 (es) 1983-04-16
ES510608A0 ES510608A0 (es) 1983-04-16

Family

ID=26377985

Family Applications (1)

Application Number Title Priority Date Filing Date
ES510608A Granted ES510608A0 (es) 1981-03-19 1982-03-18 Un derivado de 2-benzoilamino-bencilamina.

Country Status (8)

Country Link
EP (1) EP0061157A1 (es)
KR (1) KR830009000A (es)
AU (1) AU8160582A (es)
BR (1) BR8201502A (es)
DE (1) DE3209970A1 (es)
DK (1) DK110582A (es)
ES (1) ES510608A0 (es)
FI (1) FI820876A7 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6272657A (ja) * 1985-09-27 1987-04-03 Terumo Corp アミド誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤
IT1248702B (it) * 1990-06-06 1995-01-26 Yason Srl Agente antitussivo e mucoregolatore,sua preparazione e composizioni farmaceutiche

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2440546C2 (de) * 1974-08-23 1984-07-26 Johann Günter Wachswarenfabrik, 6968 Walldürn Kerze

Also Published As

Publication number Publication date
FI820876L (fi) 1982-09-20
DK110582A (da) 1982-09-20
FI820876A7 (fi) 1982-09-20
AU8160582A (en) 1982-09-23
ES510608A0 (es) 1983-04-16
DE3209970A1 (de) 1982-09-30
BR8201502A (pt) 1983-02-01
KR830009000A (ko) 1983-12-16
EP0061157A1 (en) 1982-09-29

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