ES8305775A1 - Procedimiento para la obtencion de cefalosporina 7-aca. - Google Patents

Procedimiento para la obtencion de cefalosporina 7-aca.

Info

Publication number
ES8305775A1
ES8305775A1 ES513929A ES513929A ES8305775A1 ES 8305775 A1 ES8305775 A1 ES 8305775A1 ES 513929 A ES513929 A ES 513929A ES 513929 A ES513929 A ES 513929A ES 8305775 A1 ES8305775 A1 ES 8305775A1
Authority
ES
Spain
Prior art keywords
production
cephalosporin derivatives
new cephalosporin
new
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513929A
Other languages
English (en)
Other versions
ES513929A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT576780A external-priority patent/AT373600B/de
Priority claimed from AT581980A external-priority patent/AT373601B/de
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Publication of ES8305775A1 publication Critical patent/ES8305775A1/es
Publication of ES513929A0 publication Critical patent/ES513929A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Fats And Perfumes (AREA)
  • Control Of Transmission Device (AREA)
  • Buffer Packaging (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE CEFALOSPORINA 7-ACA, DE FORMULA (I), EN LA QUE R ES HIDROGENO O METOXI; R PUEDE SER UNO DE VARIOS RADICALES; Y R ES HIDROGENO O EL RESIDUO DE UN GRUPO ESTER. CONSISTE EN LA REACCION DE DESACILACION DE UN COMPUESTO DE FORMULA (II), EN LA QUE R Y R PUEDEN SER VARIOS TIPOS DE RADICALES, Y R , R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA DESACILACION SE LLEVA A CABO SIGUIENDO METODOS CONVENCIONALES, TALES COMO LA VIA DE IMINOHALURO/IMINOETER. ESTOS COMPUESTOS TIENEN APLICACIONES PARA LA OBTENCION DE ANTIBIOTICOS DE CEFALOSPORINA.
ES513929A 1980-08-01 1982-07-13 Procedimiento para la obtencion de cefalosporina 7-aca. Granted ES513929A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT399980 1980-08-01
AT576780A AT373600B (de) 1980-11-26 1980-11-26 Verfahren zur herstellung neuer cephalosporinderivate
AT581980A AT373601B (de) 1980-11-28 1980-11-28 Verfahren zur herstellung neuer cephalosporinderivate

Publications (2)

Publication Number Publication Date
ES8305775A1 true ES8305775A1 (es) 1983-04-16
ES513929A0 ES513929A0 (es) 1983-04-16

Family

ID=27149750

Family Applications (3)

Application Number Title Priority Date Filing Date
ES504448A Granted ES504448A0 (es) 1980-08-01 1981-07-30 Procedimiento para preparar derivados de cefalosporina.
ES513929A Granted ES513929A0 (es) 1980-08-01 1982-07-13 Procedimiento para la obtencion de cefalosporina 7-aca.
ES513928A Expired ES8306486A1 (es) 1980-08-01 1982-07-13 Procedimiento para preparar olefinas polares.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES504448A Granted ES504448A0 (es) 1980-08-01 1981-07-30 Procedimiento para preparar derivados de cefalosporina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES513928A Expired ES8306486A1 (es) 1980-08-01 1982-07-13 Procedimiento para preparar olefinas polares.

Country Status (15)

Country Link
EP (1) EP0045717B1 (es)
JP (1) JPH02160791A (es)
AT (1) ATE15803T1 (es)
AU (1) AU553682B2 (es)
CA (1) CA1177064A (es)
DE (1) DE3172432D1 (es)
DK (1) DK341781A (es)
ES (3) ES504448A0 (es)
FI (1) FI78703C (es)
IE (1) IE51464B1 (es)
IL (1) IL63469A (es)
NZ (1) NZ197896A (es)
PH (1) PH22763A (es)
PT (1) PT73455B (es)
YU (1) YU44104B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT378774B (de) * 1982-08-06 1985-09-25 Biochemie Gmbh Verfahren zur deacylierung von penicillinen und cephalosporinen
IT1286520B1 (it) * 1996-12-03 1998-07-15 Antibioticos Spa Procedimento per la preparazione di intermedi utili nella sintesi di cefalosporine
PL330760A1 (en) * 1997-04-22 1999-05-24 Gist Brocades Bv Method of obatining decylated cephalosporins by fermentation process
US6518039B2 (en) * 1997-04-22 2003-02-11 Dsm N.V. Process for the fermentative production of deacylated cephalosporins
RU2221046C2 (ru) * 2000-01-21 2004-01-10 Государственный научный центр антибиотиков Способ получения полусинтетических аминопенициллинов, аминоцефалоспоринов или их n-замещенных производных

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT367060B (de) * 1979-01-25 1982-05-25 Biochemie Gmbh Verfahren zur herstellung neuer cephalosporinderivate

Also Published As

Publication number Publication date
FI78703C (fi) 1989-09-11
DK341781A (da) 1982-02-02
AU553682B2 (en) 1986-07-24
ES513928A0 (es) 1983-06-01
ES513929A0 (es) 1983-04-16
IL63469A0 (en) 1981-10-30
IE811763L (en) 1982-02-01
DE3172432D1 (en) 1985-10-31
NZ197896A (en) 1985-02-28
FI78703B (fi) 1989-05-31
EP0045717B1 (en) 1985-09-25
EP0045717A3 (en) 1982-11-10
CA1177064A (en) 1984-10-30
ES8306486A1 (es) 1983-06-01
ATE15803T1 (de) 1985-10-15
IE51464B1 (en) 1986-12-24
YU44104B (en) 1990-02-28
PT73455A (en) 1981-08-01
ES8305774A1 (es) 1983-04-16
IL63469A (en) 1985-06-30
AU7357981A (en) 1982-02-04
PT73455B (fr) 1983-02-28
PH22763A (en) 1988-12-12
FI812331L (fi) 1982-02-02
ES504448A0 (es) 1983-04-16
YU188581A (en) 1983-12-31
JPH02160791A (ja) 1990-06-20
EP0045717A2 (en) 1982-02-10

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