ES8306591A1 - Un procedimiento para la preparacion de una composicion far-maceutica a base de esteroides anti-inflamatorios - Google Patents

Un procedimiento para la preparacion de una composicion far-maceutica a base de esteroides anti-inflamatorios

Info

Publication number
ES8306591A1
ES8306591A1 ES506018A ES506018A ES8306591A1 ES 8306591 A1 ES8306591 A1 ES 8306591A1 ES 506018 A ES506018 A ES 506018A ES 506018 A ES506018 A ES 506018A ES 8306591 A1 ES8306591 A1 ES 8306591A1
Authority
ES
Spain
Prior art keywords
steroid
procedure
pharmaceutical composition
preparation
inflammatory steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506018A
Other languages
English (en)
Other versions
ES506018A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES506018A0 publication Critical patent/ES506018A0/es
Publication of ES8306591A1 publication Critical patent/ES8306591A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA LA FABRICACION DE UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN ESTEROIDE ANTI-INFLAMATORIO. SE DISUELVE EL ESTEROIDE EN UNA PARTE O EN LA TOTALIDAD DE UN ACEITE QUE POSEE UNA VISCOSIDAD MENOR DE 10 CENTISTOKES, ESTANDO INCLUIDO DICHO ACEITE EN UNA FASE ACEITOSA LIQUIDA Y REALIZANDOSE LA MEZCLA A UNA TEMPERATURA DE 30 A 90 C CON AGITACION. SE ENFRIA LA SOLUCION RESULTANTE. LA CANTIDAD DE FASE ACEITOSA LIQUIDA DEBE SER SUFICIENTE PARA DISOLVER, A 25 C, AL MENOS 3 VECES LA CANTIDAD DE ESTEROIDE QUE ESTA REALMENTE PRESENTE, Y SE ELIGEN LAS PROPORCIONES DE LOS INGREDIENTES DE TAL MODO QUE LA CONCENTRACION DEL ESTEROIDE SEA DE 0,02 A 1,5% EN PESO DE LA COMPOSICION.
ES506018A 1980-10-06 1981-10-05 Un procedimiento para la preparacion de una composicion far-maceutica a base de esteroides anti-inflamatorios Expired ES8306591A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8032111 1980-10-06

Publications (2)

Publication Number Publication Date
ES506018A0 ES506018A0 (es) 1983-06-01
ES8306591A1 true ES8306591A1 (es) 1983-06-01

Family

ID=10516496

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506018A Expired ES8306591A1 (es) 1980-10-06 1981-10-05 Un procedimiento para la preparacion de una composicion far-maceutica a base de esteroides anti-inflamatorios

Country Status (18)

Country Link
US (1) US4370322A (es)
JP (1) JPS5793907A (es)
AU (1) AU7602781A (es)
BE (1) BE890633A (es)
CA (1) CA1182048A (es)
CH (1) CH649923A5 (es)
DE (1) DE3139519A1 (es)
DK (1) DK440081A (es)
ES (1) ES8306591A1 (es)
FI (1) FI821167L (es)
FR (1) FR2491333B1 (es)
IT (1) IT1171569B (es)
NL (1) NL8104512A (es)
NO (1) NO820982L (es)
NZ (1) NZ198553A (es)
PT (1) PT73772B (es)
SE (1) SE8105867L (es)
ZA (1) ZA816872B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
US4482539A (en) * 1983-05-13 1984-11-13 Schering Corporation Betamethasone dipropionate cream
US4489070A (en) * 1983-05-13 1984-12-18 Schering Corporation Betamethasone dipropionate cream
US4515810A (en) * 1983-10-06 1985-05-07 American Cyanamid Company Composition of matter
JPS615009A (ja) * 1984-05-31 1986-01-10 Mochida Pharmaceut Co Ltd 制癌用磁性小胞体組成物
JPS62138432A (ja) * 1985-12-12 1987-06-22 Shionogi & Co Ltd 抗炎症ステロイドを含有する安定な錠剤
US5326566A (en) * 1991-05-17 1994-07-05 Bristol-Myers Squibb Company Use of dibutyl adipate and isopropyl myristate in topical and transdermal products
CA2452152A1 (en) * 2001-07-02 2002-10-10 Sinan Tas Use of cyclopamine in the treatment of psoriasis
KR20040034795A (ko) * 2002-10-17 2004-04-29 박래옥 스테로이드 제제 및 태반 추출물을 함유한 염증성 피부병치료용 경피제
FR2898499B1 (fr) * 2006-03-15 2008-11-28 Galderma Sa Nouvelles compositions topiques sous forme d'emulsion h/e comprenant un glycol pro-penetrant
FR2898498B1 (fr) * 2006-03-15 2008-11-28 Galderma Sa Nouvelles compositions topiques sous forme d'emulsion h/e comprenant un glycol pro-penetrant
US8809307B2 (en) * 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
DK2704687T3 (en) * 2011-05-04 2015-10-05 Chiesi Farma Spa Topical formulation having a corticosteroid as an active ingredient
HUE050603T2 (hu) 2015-06-18 2020-12-28 Bausch Health Ireland Ltd Egy kortikoszteroidot és egy retinoidot tartalmazó topikális készítmények psoriasis kezelésére
US11311482B2 (en) 2017-05-12 2022-04-26 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1792455A1 (de) * 1968-09-05 1971-11-11 Baerlocher Chem Verwendung von Estern natuerlicher Fettsaeuregemische in kosmetischen und pharmazeutischen Zubereitungen sowie Reinigungsmitteln und Toilettenseifen
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
US3867528A (en) * 1973-10-11 1975-02-18 American Cyanamid Co Steroidal topical cream base
US4070462A (en) * 1976-10-26 1978-01-24 Schering Corporation Steroid ointment
IT1090703B (it) * 1976-12-03 1985-06-26 Scherer Ltd R P Perfezionamento nelle composizioni utili quali veicolo per farmaci
US4083974A (en) * 1977-03-07 1978-04-11 The Upjohn Company Topical steroidal anti-inflammatory preparations containing polyoxypropylene 15 stearyl ether
NL7800762A (nl) * 1978-01-20 1979-07-24 Acf Chemiefarma Nv Vloeibare, voor injectie geschikte farmaceu- tische samenstellingen.
US4233295A (en) * 1979-05-31 1980-11-11 E. R. Squibb & Sons, Inc. Corticosteroid formulations containing sebacate carrier

Also Published As

Publication number Publication date
PT73772A (en) 1981-11-01
DE3139519A1 (de) 1982-06-16
SE8105867L (sv) 1982-04-07
IT8149422A1 (it) 1983-04-05
NL8104512A (nl) 1982-05-03
ES506018A0 (es) 1983-06-01
IT1171569B (it) 1987-06-10
PT73772B (en) 1983-10-14
CA1182048A (en) 1985-02-05
ZA816872B (en) 1982-09-29
FR2491333B1 (fr) 1985-09-27
FI821167A0 (fi) 1982-04-02
FI821167A7 (fi) 1983-10-03
CH649923A5 (de) 1985-06-28
BE890633A (fr) 1982-04-05
FR2491333A1 (fr) 1982-04-09
NZ198553A (en) 1983-09-30
AU7602781A (en) 1982-04-22
IT8149422A0 (it) 1981-10-05
US4370322A (en) 1983-01-25
DK440081A (da) 1982-04-07
NO820982L (no) 1983-09-26
FI821167L (fi) 1983-10-03
JPS5793907A (en) 1982-06-11

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