ES8307101A1 - "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza". - Google Patents

"procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza".

Info

Publication number
ES8307101A1
ES8307101A1 ES511716A ES511716A ES8307101A1 ES 8307101 A1 ES8307101 A1 ES 8307101A1 ES 511716 A ES511716 A ES 511716A ES 511716 A ES511716 A ES 511716A ES 8307101 A1 ES8307101 A1 ES 8307101A1
Authority
ES
Spain
Prior art keywords
prepn
high purity
peg
factor viii
factor concentrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511716A
Other languages
English (en)
Other versions
ES511716A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Hubber SA
Original Assignee
Laboratorios Hubber SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Hubber SA filed Critical Laboratorios Hubber SA
Priority to ES511716A priority Critical patent/ES511716A0/es
Publication of ES8307101A1 publication Critical patent/ES8307101A1/es
Publication of ES511716A0 publication Critical patent/ES511716A0/es
Granted legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER UN PREPARADO CONCENTRADO DE FACTOR ANTIHEMOFILICO DE ALTA PUREZA, EXENTO PRACTICAMENTE DE FIBRINOGENO. SE BASA EN LA PURIFICACION DE CRIOPRECIPITADO EN FRIO, EXTRACCION DEL FACTOR VIII EN TAMPON TRIS/CLH, DESACTIVACION DEL COMPLEJO PROTROMBINICO CON HEPARINA, PRECIPITACION SELECTIVA DEL FIBRINOGENO CON PEG Y POSTERIOR PURIFICACION DEL FACTOR VIII CON PEG, ELIMINACION DE LA HEPARINA Y PEG RESIDUAL SIN PERDIDA DE FACTOR VIII. EL CRIOPRECIPITADO SE OBTIENE SIN ETANOL FRIO, DEJANDO QUE LA FRACCION CRIOPRECIPITABLE LO HAGA POR SI MISMA Y EN TIEMPO RELATIVAMENTE CORTO, NO SUPERIOR A LAS DOS HORAS Y A UNA TEMPERATURA ENTRE 0 C Y 2 C
ES511716A 1982-04-26 1982-04-26 "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza". Granted ES511716A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES511716A ES511716A0 (es) 1982-04-26 1982-04-26 "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES511716A ES511716A0 (es) 1982-04-26 1982-04-26 "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza".

Publications (2)

Publication Number Publication Date
ES8307101A1 true ES8307101A1 (es) 1983-07-01
ES511716A0 ES511716A0 (es) 1983-07-01

Family

ID=8484060

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511716A Granted ES511716A0 (es) 1982-04-26 1982-04-26 "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza".

Country Status (1)

Country Link
ES (1) ES511716A0 (es)

Also Published As

Publication number Publication date
ES511716A0 (es) 1983-07-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612