ES8307220A1 - "procedimiento para preparar derivados de dihidropiridina". - Google Patents

"procedimiento para preparar derivados de dihidropiridina".

Info

Publication number
ES8307220A1
ES8307220A1 ES508024A ES508024A ES8307220A1 ES 8307220 A1 ES8307220 A1 ES 8307220A1 ES 508024 A ES508024 A ES 508024A ES 508024 A ES508024 A ES 508024A ES 8307220 A1 ES8307220 A1 ES 8307220A1
Authority
ES
Spain
Prior art keywords
ch2och3
ch2ch2och3
dihydropyridine
procedure
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508024A
Other languages
English (en)
Other versions
ES508024A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Publication of ES8307220A1 publication Critical patent/ES8307220A1/es
Publication of ES508024A0 publication Critical patent/ES508024A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE DIHIDROPIRIDINA. CONSISTE EN HACER REACCIONAR EL COMPUESTO (I) CON LOS COMPUESTOS (II) Y (III) O BIEN CON LOS COMPUESTOS (IV) Y (V) OPCIONALMENTE PUEDE HACERSE REACCIONAR EL COMPUESTO (I) CON LOS COMPUESTOS (II) Y (IV) EN PRESENCIA DE AMONIACO. SE OBTIENE EL COMPUESTO (VI) EN QUE R C ES -CH , -CH CH OCH O -CH(CH )CH -OCH ; R ES -CH E, -C H , -CH CH OCH O -CH(CH )CH OCH ; R SE SELECCIONA ENTRE UN ALCOHILO DE 2 A 3 ATOMOS DE CARBONO, UN ALCOXI ALCOHILO DE 2 A 3 ATOMOS DE CARBONO; O ALCOXI ALCOXIALCOHILO CON 3 A 5 ATOMOS DE CARBONO.
ES508024A 1979-12-20 1981-12-16 "procedimiento para preparar derivados de dihidropiridina". Granted ES508024A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7910521A SE7910521L (sv) 1979-12-20 1979-12-20 Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Publications (2)

Publication Number Publication Date
ES8307220A1 true ES8307220A1 (es) 1982-11-16
ES508024A0 ES508024A0 (es) 1982-11-16

Family

ID=20339605

Family Applications (4)

Application Number Title Priority Date Filing Date
ES497927A Granted ES497927A0 (es) 1979-12-20 1980-12-19 Procedimiento para preparar derivados de dihidropiridina
ES508025A Granted ES508025A0 (es) 1979-12-20 1981-12-16 "procedimiento para preparar derivados de dihidropiridina".
ES508024A Granted ES508024A0 (es) 1979-12-20 1981-12-16 "procedimiento para preparar derivados de dihidropiridina".
ES508031A Granted ES508031A0 (es) 1979-12-20 1981-12-16 Procedimiento para preparar derivados de dihidropiridina.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES497927A Granted ES497927A0 (es) 1979-12-20 1980-12-19 Procedimiento para preparar derivados de dihidropiridina
ES508025A Granted ES508025A0 (es) 1979-12-20 1981-12-16 "procedimiento para preparar derivados de dihidropiridina".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES508031A Granted ES508031A0 (es) 1979-12-20 1981-12-16 Procedimiento para preparar derivados de dihidropiridina.

Country Status (11)

Country Link
EP (1) EP0031801A3 (es)
JP (1) JPS56127356A (es)
AU (1) AU6542380A (es)
DD (1) DD155519A5 (es)
DK (1) DK539980A (es)
ES (4) ES497927A0 (es)
FI (1) FI803984L (es)
MY (1) MY8500404A (es)
NO (1) NO803856L (es)
SE (1) SE7910521L (es)
ZA (1) ZA807634B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3018259A1 (de) * 1980-05-13 1981-11-19 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
ATE20064T1 (de) * 1982-07-22 1986-06-15 Pfizer Anti-ischaemische und antihypertensive dihydropyridin-derivate.
HU192166B (en) * 1982-08-06 1987-05-28 Banyu Pharma Co Ltd Process for producing 2-carbamoyl-oxy-alkyl-1,4-dihydro-pyridine derivatives
EP0107293A3 (en) * 1982-09-04 1984-06-06 Pfizer Limited Dihydropyridines
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
PL140069B1 (en) * 1982-12-21 1987-03-31 Pfizer Method of obtaining new derivatives of dihydropiridine
US4515799A (en) * 1983-02-02 1985-05-07 Pfizer Inc. Dihydropyridine anti-ischaemic and antihypertensive agents
GB8306666D0 (en) * 1983-03-10 1983-04-13 Pfizer Ltd Therapeutic agents
GB8412208D0 (en) * 1984-05-12 1984-06-20 Pfizer Ltd Quinolone inotropic agents
GB8415386D0 (en) * 1984-06-15 1984-07-18 Pfizer Ltd Therapeutic agents
GB8526411D0 (en) * 1985-10-25 1985-11-27 Pfizer Ltd Dihydropyridines
GB8527698D0 (en) * 1985-11-09 1985-12-11 Pfizer Ltd Dihydropyridine antiischaemic & antihypertensive agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117572C3 (de) * 1971-04-10 1980-03-20 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
ES8307221A1 (es) 1982-11-01
ZA807634B (en) 1981-11-25
MY8500404A (en) 1985-12-31
ES508025A0 (es) 1982-11-01
NO803856L (no) 1981-06-22
JPS56127356A (en) 1981-10-06
SE7910521L (sv) 1981-06-21
ES508024A0 (es) 1982-11-16
DD155519A5 (de) 1982-06-16
EP0031801A3 (en) 1981-09-16
AU6542380A (en) 1981-06-25
DK539980A (da) 1981-06-21
ES8306109A1 (es) 1982-10-01
FI803984A7 (fi) 1981-06-21
ES508031A0 (es) 1982-10-01
ES8204720A1 (es) 1982-05-01
ES497927A0 (es) 1982-05-01
FI803984L (fi) 1981-06-21
EP0031801A2 (en) 1981-07-08

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