ES8307738A1 - "un procedimiento para convertir olefinas en los correspondientes alfa-epoxi-alcoholes". - Google Patents

"un procedimiento para convertir olefinas en los correspondientes alfa-epoxi-alcoholes".

Info

Publication number
ES8307738A1
ES8307738A1 ES510008A ES510008A ES8307738A1 ES 8307738 A1 ES8307738 A1 ES 8307738A1 ES 510008 A ES510008 A ES 510008A ES 510008 A ES510008 A ES 510008A ES 8307738 A1 ES8307738 A1 ES 8307738A1
Authority
ES
Spain
Prior art keywords
olefin
making same
epoxi
mono
prostaglandin analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510008A
Other languages
English (en)
Other versions
ES510008A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of ES8307738A1 publication Critical patent/ES8307738A1/es
Publication of ES510008A0 publication Critical patent/ES510008A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

UN PROCEDIMIENTO PARA CONVERTIR OLEFINAS EN LOS CORRESPNDIENTES ALFA-EPOXI-ALCOHOLES. CONSISTE EN HACER REACCIONAR UNA OLEFINA CON OXIGENO, CONVIRTIENDO EL PRODUCTO DE REACCION EN UN ALFA-EPOXI-ALCOHOL POR TRANSPOSICION IN SITU, EN PRESENCIA DE UNA CANTIDAD CATALITICA DE UN CATALIZADOR HETEROGENEO U HOMOGENEO QUE CONTIENE UN METAL DE TRANSICION DE LOS GRUPOS CUATRO, CINCO Y SEIS B CON EXCLUSION DEL BROMO. LA MEZCLA DE REACCION COMPRENDE UNA MONO-OLEFINA QUE VA DEL 5 AL 98% DE UN DISOLVENTE ORGANICO QUE ES MIXIBLE CON DICHA MONO-OLEFINA Y UNA CANTIDAD CATALITICA DE UNA SAL SOLUBLE O UN COMPLEJO METALO-ORGANICO DE VANADIO O MOLIBDENO.
ES510008A 1981-03-02 1982-03-01 "un procedimiento para convertir olefinas en los correspondientes alfa-epoxi-alcoholes". Granted ES510008A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/239,765 US4345984A (en) 1981-03-02 1981-03-02 Novel prostaglandin analogues and process for making same

Publications (2)

Publication Number Publication Date
ES8307738A1 true ES8307738A1 (es) 1983-07-01
ES510008A0 ES510008A0 (es) 1983-07-01

Family

ID=22903636

Family Applications (3)

Application Number Title Priority Date Filing Date
ES510008A Granted ES510008A0 (es) 1981-03-02 1982-03-01 "un procedimiento para convertir olefinas en los correspondientes alfa-epoxi-alcoholes".
ES519902A Granted ES519902A0 (es) 1981-03-02 1983-02-18 Un procedimiento para sintetizar analogos de 7-oxa-11-desoxiprostaglandina.
ES519903A Granted ES519903A0 (es) 1981-03-02 1983-02-18 Un procedimiento para convertir analogos de 7-oxa-11-desoxi-prostaglandina en otros analogos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES519902A Granted ES519902A0 (es) 1981-03-02 1983-02-18 Un procedimiento para sintetizar analogos de 7-oxa-11-desoxiprostaglandina.
ES519903A Granted ES519903A0 (es) 1981-03-02 1983-02-18 Un procedimiento para convertir analogos de 7-oxa-11-desoxi-prostaglandina en otros analogos.

Country Status (12)

Country Link
US (1) US4345984A (es)
EP (1) EP0061209B1 (es)
JP (1) JPS57206654A (es)
AT (1) ATE15368T1 (es)
AU (2) AU548052B2 (es)
CA (1) CA1210016A (es)
DE (1) DE3265945D1 (es)
ES (3) ES510008A0 (es)
IE (1) IE52623B1 (es)
MX (1) MX7354E (es)
NZ (1) NZ199807A (es)
ZA (1) ZA821102B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383904A (en) * 1981-09-21 1983-05-17 Celanese Corporation Photochemical epoxidation
US4576962A (en) * 1983-10-19 1986-03-18 The Procter & Gamble Company Prostaglandin analogues
NL8501429A (nl) * 1984-05-18 1985-12-16 Glaxo Group Ltd Aminocyclopentylethers, hun bereiding en farmaceutische preparaten ervan.
US4851555A (en) * 1984-10-25 1989-07-25 Scientific Design Company, Inc. Process for preparing alkylene oxides from alkylene carbonates
IL84414A0 (en) * 1986-11-14 1988-04-29 Ciba Geigy Ag N9-cyclopentyl-substituted adenine derivatives
EP0660814A1 (de) * 1992-09-16 1995-07-05 Hoechst Aktiengesellschaft Verfahren zur sensibilisierten photooxygenierung von ungesättigten verbindungen
US6674781B1 (en) * 2002-08-19 2004-01-06 The Boeing Company Method and system for fueling a closed cycle chemical oxygen iodine laser
EP2266998B1 (en) * 2009-06-16 2013-07-24 Crystal Pharma, S.A.U. Process for obtaining 17-spirolactones in steroids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131724C (es) * 1962-11-20
US4175201A (en) * 1973-05-18 1979-11-20 University Of Chicago Chemical synthesis
US4021369A (en) * 1973-06-29 1977-05-03 Sun Ventures, Inc. Ion-exchanged transition metal catalysts for the direct oxidation of olefins to epoxyalcohols
US4123445A (en) * 1974-11-13 1978-10-31 Sun Ventures, Inc. Novel homogeneous transition-metal catalyzed geometric isomerization of cyclic epoxy alcohols
US4180672A (en) * 1976-08-13 1979-12-25 Teijin Limited 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom

Also Published As

Publication number Publication date
DE3265945D1 (en) 1985-10-10
IE820450L (en) 1982-09-02
ES8500224A1 (es) 1984-10-01
AU8063282A (en) 1982-09-09
ATE15368T1 (de) 1985-09-15
MX7354E (es) 1988-07-19
AU548052B2 (en) 1985-11-21
EP0061209B1 (en) 1985-09-04
NZ199807A (en) 1985-11-08
ES8403451A1 (es) 1984-03-16
EP0061209A1 (en) 1982-09-29
CA1210016A (en) 1986-08-19
JPS57206654A (en) 1982-12-18
ZA821102B (en) 1983-01-26
IE52623B1 (en) 1988-01-06
US4345984A (en) 1982-08-24
AU4655885A (en) 1985-12-05
ES510008A0 (es) 1983-07-01
ES519903A0 (es) 1984-10-01
ES519902A0 (es) 1984-03-16

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