ES8307768A1 - Un procedimiento para la preparacion de nuevos derivados de 1,2,4 triazol. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de 1,2,4 triazol.

Info

Publication number
ES8307768A1
ES8307768A1 ES513032A ES513032A ES8307768A1 ES 8307768 A1 ES8307768 A1 ES 8307768A1 ES 513032 A ES513032 A ES 513032A ES 513032 A ES513032 A ES 513032A ES 8307768 A1 ES8307768 A1 ES 8307768A1
Authority
ES
Spain
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
triazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513032A
Other languages
English (en)
Other versions
ES513032A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES8307768A1 publication Critical patent/ES8307768A1/es
Publication of ES513032A0 publication Critical patent/ES513032A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 1,2,4-TRIAZOL, DE SUS SALES, HIDRATOS Y BIOPRECURSORES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE ALK ES ALQUILENO C<1<-<6; Q, X, R<1, R<2, R<3 Y R<4 PUEDEN SER VARIOS RADICALES; Y M Y N VALEN 2-5 Y 0-2, RESPECTIVAMENTE. CONSISTE EN LA REACCION DE UN ALCOHOL, DE FORMULA VOH, CON UN DERIVADO ACTIVADO DE UN ACIDO, DE FORMULA WCOL, EN LAS QUE V, W Y L PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA COMPRENDIDA ENTRE 100 C Y 170 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA INHIBIR LA SECRECION DEL ACIDO GASTRICO.
ES513032A 1981-06-11 1982-06-11 Un procedimiento para la preparacion de nuevos derivados de 1,2,4 triazol. Granted ES513032A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8117955 1981-06-11
GB8122605 1981-07-22

Publications (2)

Publication Number Publication Date
ES8307768A1 true ES8307768A1 (es) 1983-08-01
ES513032A0 ES513032A0 (es) 1983-08-01

Family

ID=26279760

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513032A Granted ES513032A0 (es) 1981-06-11 1982-06-11 Un procedimiento para la preparacion de nuevos derivados de 1,2,4 triazol.

Country Status (6)

Country Link
US (1) US4476126A (es)
EP (1) EP0070097A1 (es)
AU (1) AU8480982A (es)
CA (1) CA1173032A (es)
ES (1) ES513032A0 (es)
NZ (1) NZ200921A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100467668B1 (ko) * 2002-08-07 2005-01-24 씨제이 주식회사 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2023133B (en) * 1978-04-26 1982-09-08 Glaxo Group Ltd Heterocyclic derivatives
ZA801151B (en) * 1979-03-02 1981-02-25 Glaxo Group Ltd Heterocyclic derivatives
PT70884A (en) * 1979-03-02 1980-03-01 Glaxo Group Ltd Process for preparing heterocyclic derivatives
DE3067564D1 (en) * 1979-10-22 1984-05-24 Glaxo Group Ltd 1,2,4-triazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
EP0029303B1 (en) * 1979-10-22 1985-01-30 Glaxo Group Limited 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them
DE3068712D1 (en) * 1979-10-23 1984-08-30 Glaxo Group Ltd Aminoalkyl compounds, their production and pharmaceutical compositions containing them
DE3067019D1 (en) * 1979-10-23 1984-04-19 Glaxo Group Ltd Thiophene derivatives, processes for the production thereof and pharmaceutical compositions containing them
CH655104A5 (fr) * 1980-02-28 1986-03-27 Glaxo Group Ltd Derives heterocycliques triazoliques, procedes pour leur preparation et compositions pharmaceutiques les comportant.
EP0048555B1 (en) * 1980-08-27 1985-12-04 Glaxo Group Limited Amino-1,2,4-triazole derivatives, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NZ200921A (en) 1985-07-12
CA1173032A (en) 1984-08-21
ES513032A0 (es) 1983-08-01
EP0070097A1 (en) 1983-01-19
AU8480982A (en) 1983-01-13
US4476126A (en) 1984-10-09

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