ES8308357A1 - Production of L-lysine by fermentation and new microorganisms obtained by protoplast fusion - Google Patents

Production of L-lysine by fermentation and new microorganisms obtained by protoplast fusion

Info

Publication number
ES8308357A1
ES8308357A1 ES514806A ES514806A ES8308357A1 ES 8308357 A1 ES8308357 A1 ES 8308357A1 ES 514806 A ES514806 A ES 514806A ES 514806 A ES514806 A ES 514806A ES 8308357 A1 ES8308357 A1 ES 8308357A1
Authority
ES
Spain
Prior art keywords
lysine
production
fermentation
protoplast fusion
microorganism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514806A
Other languages
Spanish (es)
Other versions
ES514806A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56125006A external-priority patent/JPS5828292A/en
Priority claimed from JP56182095A external-priority patent/JPS5886094A/en
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of ES8308357A1 publication Critical patent/ES8308357A1/en
Publication of ES514806A0 publication Critical patent/ES514806A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PRODUCCION DE L-LISINA. CONSISTE EN CULTIVAR UN MICROORGANISMO OBTENIDO POR FUSION PROTOPLASTICA Y CAPAZ DE PRODUCIR L-LISINA EN UN MEDIO NUTRIENTE, FORMAR Y ACUMULAR L-LISINA EN EL CALDO DE CULTIVO RESULTANTE Y RECUPERAR LA L-LISINA DEL MISMO. EL MICROORGANISMO CULTIVADO ES DEL GENERO CORYNECABTERIUM O BREVIBACTERIUM. DICHO MICROORGANISMO ES RESISTENTE A DOS O MAS ANTIBIOTICOS Y ASI MISMO A UN ANALOGO DE LA PIRIMIDINA; LOS ANTIBIOTICOS SE SELECCIONAN DE ENTRE EL GRUPO FORMADO POR LOS TIPOS AMINOGLICOSIDICO, ~J-LACTAMICO, MACROLIDICO Y RIFAMICINICO.A PROCEDURE FOR THE PRODUCTION OF L-LYSINE. IT CONSISTS OF CULTIVATING A MICROORGANISM OBTAINED BY PROTOPLASTIC FUSION AND CAPABLE OF PRODUCING L-LYSINE IN A NUTRIENT MEDIUM, FORMING AND ACCUMULATING L-LYSINE IN THE RESULTING CULTIVATION BROTH AND RECOVERING THE L-LYSINE FROM THE SAME. THE CULTIVATED MICROORGANISM IS OF THE GENUS CORYNECABTERIUM OR BREVIBACTERIUM. SUCH MICROORGANISM IS RESISTANT TO TWO OR MORE ANTIBIOTICS AND ALSO TO A PYRIMIDINE ANALOGUE; ANTIBIOTICS ARE SELECTED FROM THE GROUP FORMED BY THE AMINOGLYCOSIDIC, ~J-LACTAMIC, MACROLIDIC AND RIPHAMYCINIC TYPES.

ES514806A 1981-08-10 1982-08-06 A PROCEDURE FOR THE PRODUCTION OF L-LYSINE. Granted ES514806A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP56125006A JPS5828292A (en) 1981-08-10 1981-08-10 Preparation of l-lysine by fermentation
JP56182095A JPS5886094A (en) 1981-11-13 1981-11-13 Preparation of l-lysine by fermentation

Publications (2)

Publication Number Publication Date
ES8308357A1 true ES8308357A1 (en) 1983-08-16
ES514806A0 ES514806A0 (en) 1983-08-16

Family

ID=26461548

Family Applications (1)

Application Number Title Priority Date Filing Date
ES514806A Granted ES514806A0 (en) 1981-08-10 1982-08-06 A PROCEDURE FOR THE PRODUCTION OF L-LYSINE.

Country Status (6)

Country Link
AU (1) AU553843B2 (en)
ES (1) ES514806A0 (en)
FR (1) FR2511035B1 (en)
GB (2) GB2103617B (en)
IN (1) IN155754B (en)
IT (1) IT1156487B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59113894A (en) * 1982-12-17 1984-06-30 Kyowa Hakko Kogyo Co Ltd Preparation of l-glutamic acid by fermentation
EP0136359B1 (en) * 1983-02-17 1991-04-03 Kyowa Hakko Kogyo Kabushiki Kaisha Process for preparing l-histidine
CA1213228A (en) * 1983-04-13 1986-10-28 Peter S. Carlson Agricultural-chemical-producing endosymbiotic bacteria and method of preparing and using same
GB2151436A (en) * 1983-12-09 1985-07-17 Philips Electronic Associated Duplex speech transmission method and a system therefor
JPS61282092A (en) * 1985-06-10 1986-12-12 Ajinomoto Co Inc Production of l-lysine by fermentation method
JPS6261592A (en) * 1985-09-13 1987-03-18 Ajinomoto Co Inc Separation of basic amino acid
JPS6312292A (en) * 1986-07-03 1988-01-19 Kyowa Hakko Kogyo Co Ltd Production of l-lysine
JP2578463B2 (en) * 1988-02-03 1997-02-05 協和醗酵工業株式会社 Production method of L-lysine by fermentation method
KR910002850B1 (en) * 1989-03-30 1991-05-06 제일제당 주식회사 Mycrobi for producing l-lysing and process for preparing l-lysin from it
JP2943312B2 (en) * 1990-10-29 1999-08-30 味の素株式会社 Production method of L-lysine by fermentation method
DE4203320C2 (en) * 1992-02-06 1994-02-03 Forschungszentrum Juelich Gmbh Fermentation process for the extraction of amino acids and a suitable bacterial strain
CN1165619C (en) * 1995-06-07 2004-09-08 味之素株式会社 Process for producing L-lysine
AU2002241329A1 (en) * 2001-03-30 2002-10-15 Fujisawa Pharmaceutical Co., Ltd. Method for increasing the production of a secondary metabolite in a microorganism by introducing mutations that confer antibiotic-resistance
DE102005043979A1 (en) 2005-09-15 2007-03-22 Forschungszentrum Jülich GmbH Process for the production of amino acids in amino acid-producing microorganisms

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5544597B1 (en) * 1969-06-09 1980-11-13
JPS539394A (en) * 1976-07-09 1978-01-27 Kyowa Hakko Kogyo Co Ltd Preparation of l-lysine by fermentation

Also Published As

Publication number Publication date
GB8505658D0 (en) 1985-04-03
IN155754B (en) 1985-03-02
AU8702882A (en) 1983-05-19
FR2511035B1 (en) 1985-07-26
IT8267997A0 (en) 1982-08-09
GB2152509A (en) 1985-08-07
ES514806A0 (en) 1983-08-16
FR2511035A1 (en) 1983-02-11
GB2103617B (en) 1986-05-21
GB2103617A (en) 1983-02-23
AU553843B2 (en) 1986-07-31
IT1156487B (en) 1987-02-04
GB2152509B (en) 1986-05-21
IT8267997A1 (en) 1984-04-08

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519