ES8308544A1 - Procedimiento para la obtencion de derivados de diaril-imidazol. - Google Patents

Procedimiento para la obtencion de derivados de diaril-imidazol.

Info

Publication number
ES8308544A1
ES8308544A1 ES514478A ES514478A ES8308544A1 ES 8308544 A1 ES8308544 A1 ES 8308544A1 ES 514478 A ES514478 A ES 514478A ES 514478 A ES514478 A ES 514478A ES 8308544 A1 ES8308544 A1 ES 8308544A1
Authority
ES
Spain
Prior art keywords
formula
procedure
obtaining
rest
diaril
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514478A
Other languages
English (en)
Other versions
ES514478A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES514478A0 publication Critical patent/ES514478A0/es
Publication of ES8308544A1 publication Critical patent/ES8308544A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE DIARIL-IMIZADOL DE FORMULA (I), EN LA QUE R<1 Y R<2, INDEPENDIENTES ENTRE SI, SIGNIFICAN ARILO CARBOCICLICO O HETEROARILO; R<3 SIGNIFICA UN RESTO DE FORMULA -ALK-A-R<4, EN LA QUE ALK SIGNIFICA UN RESTO DE HIDROCARBURO DIVALENTE; A SIGNIFICA UN GRUPO DE FORMULA -O- O -S(O)<N-; N ES 0, 1 O 2; Y R<4 SIGNIFICA UN RESTO DE HIDROCARBURO, EN CASO DADO SUBSTITUIDO, Y SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN REDUCIR UN COMPUESTO DE FORMULA (II) O UNA SAL DEL MISMO, A UN COMPUESTO DE FORMULA (I). DE APLICACION EN FARMACIA POR SUS EFECTOS ANTIINFLAMATORIOS.
ES514478A 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol. Expired ES8308544A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH625580 1980-08-19

Publications (2)

Publication Number Publication Date
ES514478A0 ES514478A0 (es) 1983-05-01
ES8308544A1 true ES8308544A1 (es) 1983-05-01

Family

ID=4306702

Family Applications (11)

Application Number Title Priority Date Filing Date
ES504787A Expired ES8308881A1 (es) 1980-08-19 1981-08-17 Procedimiento para la obtencion de derivados de diaril-imi- dazol
ES514481A Granted ES514481A0 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES514479A Expired ES8308545A1 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES514480A Granted ES514480A0 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES514482A Granted ES514482A0 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES514478A Expired ES8308544A1 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES522921A Granted ES522921A0 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES522925A Expired ES8504137A1 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.(como desglose y con prioridad de la patente espanola n 504.787, presentada el 17 de agosto de 1981)
ES522922A Granted ES522922A0 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES522923A Granted ES522923A0 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.(como desglose y con prioridad de la patente espanola n 504.787, presentada el 17 de agosto de 1981)
ES522924A Expired ES8504136A1 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.(como desglose y con prioridad de la patente espanola n 504.787, presentada el 17 de agosto de 1981)

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES504787A Expired ES8308881A1 (es) 1980-08-19 1981-08-17 Procedimiento para la obtencion de derivados de diaril-imi- dazol
ES514481A Granted ES514481A0 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES514479A Expired ES8308545A1 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES514480A Granted ES514480A0 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES514482A Granted ES514482A0 (es) 1980-08-19 1982-07-28 Procedimiento para la obtencion de derivados de diaril-imidazol.

Family Applications After (5)

Application Number Title Priority Date Filing Date
ES522921A Granted ES522921A0 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES522925A Expired ES8504137A1 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.(como desglose y con prioridad de la patente espanola n 504.787, presentada el 17 de agosto de 1981)
ES522922A Granted ES522922A0 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.
ES522923A Granted ES522923A0 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.(como desglose y con prioridad de la patente espanola n 504.787, presentada el 17 de agosto de 1981)
ES522924A Expired ES8504136A1 (es) 1980-08-19 1983-06-01 Procedimiento para la obtencion de derivados de diaril-imidazol.(como desglose y con prioridad de la patente espanola n 504.787, presentada el 17 de agosto de 1981)

Country Status (14)

Country Link
EP (1) EP0046451A3 (es)
JP (1) JPS5770873A (es)
KR (1) KR830006279A (es)
AU (1) AU7427881A (es)
DD (1) DD201788A5 (es)
DK (1) DK366081A (es)
ES (11) ES8308881A1 (es)
FI (1) FI812536L (es)
GR (1) GR75316B (es)
IL (1) IL63595A (es)
NO (1) NO812790L (es)
NZ (1) NZ198074A (es)
PT (1) PT73536A (es)
ZA (1) ZA815684B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4616085A (en) * 1980-06-19 1986-10-07 Petrolite Corporation Thioethers of imidazolines
US5916891A (en) 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
EP1306377A3 (en) * 1993-11-08 2003-05-07 Smithkline Beecham Corporation Pyridyl-oxazoles and their use as cytokines inhibitors
DE69723267T2 (de) 1996-04-25 2004-04-22 Nissan Chemical Industries, Ltd. Ethylenderivate und pestizide
DE19811692A1 (de) 1998-03-18 1999-09-23 Merck Patent Gmbh Sonnenschutzformulierungen mit Wirkung gegen Herpes Simplex Viren
DE19837758A1 (de) * 1998-08-20 2000-02-24 Beiersdorf Ag Verwendung von Wirkstoffkombinationen aus Flavonoiden und UV-Filtersubstanzen als antivirales Wirkprinzip

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5343958B2 (es) * 1972-07-29 1978-11-24
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
ES8504135A1 (es) 1985-04-01
ES8507506A1 (es) 1985-09-16
JPS5770873A (en) 1982-05-01
ZA815684B (en) 1982-08-25
ES514479A0 (es) 1983-05-01
EP0046451A3 (de) 1982-04-21
ES522925A0 (es) 1985-04-01
ES8308547A1 (es) 1983-05-01
ES504787A0 (es) 1983-10-01
ES8308546A1 (es) 1983-05-01
ES8401759A1 (es) 1983-05-01
DK366081A (da) 1982-02-20
PT73536A (en) 1981-09-01
IL63595A (en) 1985-04-30
EP0046451A2 (de) 1982-02-24
ES8308545A1 (es) 1983-05-01
ES514480A0 (es) 1983-05-01
AU7427881A (en) 1982-02-25
ES8504137A1 (es) 1985-04-01
ES514482A0 (es) 1983-05-01
GR75316B (es) 1984-07-13
ES522924A0 (es) 1985-04-01
ES514481A0 (es) 1983-05-01
ES514478A0 (es) 1983-05-01
ES8504136A1 (es) 1985-04-01
FI812536A7 (fi) 1982-02-20
ES8503668A1 (es) 1985-03-01
ES522923A0 (es) 1985-04-01
DD201788A5 (de) 1983-08-10
NO812790L (no) 1982-02-22
KR830006279A (ko) 1983-09-20
ES8308881A1 (es) 1983-10-01
IL63595A0 (en) 1981-11-30
FI812536L (fi) 1982-02-20
ES522922A0 (es) 1985-03-01
NZ198074A (en) 1985-07-12
ES522921A0 (es) 1985-09-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991007