ES8308833A1 - "un metodo para la preparacion de 3-fenil-1-indanaminas". - Google Patents

"un metodo para la preparacion de 3-fenil-1-indanaminas".

Info

Publication number
ES8308833A1
ES8308833A1 ES516184A ES516184A ES8308833A1 ES 8308833 A1 ES8308833 A1 ES 8308833A1 ES 516184 A ES516184 A ES 516184A ES 516184 A ES516184 A ES 516184A ES 8308833 A1 ES8308833 A1 ES 8308833A1
Authority
ES
Spain
Prior art keywords
compounds
indanamines
phenyl
preparation
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516184A
Other languages
English (en)
Other versions
ES516184A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Kefalas AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS, Kefalas AS filed Critical H Lundbeck AS
Publication of ES8308833A1 publication Critical patent/ES8308833A1/es
Publication of ES516184A0 publication Critical patent/ES516184A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 3-FENIL-L-INDANAMINAS Y SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R>1, R>2, R>3, R>4, R>5 Y R>6 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA NHR>4R>5, EN LAS QUE X ES CLORO O -OS<2R, SIENDO R METILO O P-TOLILO; Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, TAL COMO EL ETANOL, A LA TEMPERATURA DE REFLUJO, EN UN AUTOCLAVE DE ACERO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD TIMOLEPTICA.
ES516184A 1981-10-05 1982-10-04 "un metodo para la preparacion de 3-fenil-1-indanaminas". Granted ES516184A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8130009 1981-10-05

Publications (2)

Publication Number Publication Date
ES8308833A1 true ES8308833A1 (es) 1983-10-01
ES516184A0 ES516184A0 (es) 1983-10-01

Family

ID=10524953

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516184A Granted ES516184A0 (es) 1981-10-05 1982-10-04 "un metodo para la preparacion de 3-fenil-1-indanaminas".

Country Status (11)

Country Link
EP (1) EP0076669A1 (es)
JP (1) JPS5877846A (es)
AU (1) AU8898282A (es)
DK (1) DK438482A (es)
ES (1) ES516184A0 (es)
FI (1) FI823360L (es)
GR (1) GR76712B (es)
IL (1) IL66831A0 (es)
NO (1) NO823344L (es)
PT (1) PT75636B (es)
ZA (1) ZA826924B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866208A (en) * 1981-12-21 1989-09-12 The Dow Chemical Company Meta-phenylene diamine derivatives
JPS6169747A (ja) * 1984-08-31 1986-04-10 Otsuka Pharmaceut Co Ltd ２，３―ジヒドロ―１ｈ―インデン誘導体及びその製造法
EP0173331B1 (en) * 1984-08-31 1991-08-14 Otsuka Pharmaceutical Co., Ltd. 2,3-dihydro-1h-indene derivatives, a process for preparing them and pharmaceutical compositions containing same
GB8628644D0 (en) * 1986-12-01 1987-01-07 Lunbeck A S H Intermediates
AU4078397A (en) * 1996-08-16 1998-03-06 Allelix Pharm-Eco, L.L.P. Slow-onset, long-lasting dopamine reuptake blockers
US5821386A (en) * 1997-08-15 1998-10-13 Allelix-Pharm-Eco L.P. Compounds for treating cocaine abuse
EP1044184A1 (en) * 1998-01-09 2000-10-18 Pharm-Eco Laboratoires, Incorporated Synthesis of 3-aryl-1-indanamines
DE19955190A1 (de) * 1999-11-16 2001-06-21 Sanol Arznei Schwarz Gmbh Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
WO2014064257A1 (en) 2012-10-26 2014-05-01 Nlife Therapeutics, S.L. Compositions and methods for the treatment of parkinson disease by the selective delivery of oligonucleotide molecules to specific neuron types

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE955594C (de) * 1953-11-15 1957-01-03 Schering Ag Verfahren zur Herstellung von 3-Aminoindanen
GB971917A (en) * 1960-11-08 1964-10-07 Schering Ag New aminoindanes and a process for their manufacture
DE2339715A1 (de) * 1973-08-06 1975-02-27 Hoechst Ag Basisch substituierte phenylindane und verfahren zu ihrer herstellung
IE50867B1 (en) * 1980-02-29 1986-08-06 Kefalas As Indane derivatives

Also Published As

Publication number Publication date
JPS5877846A (ja) 1983-05-11
IL66831A0 (en) 1982-12-31
NO823344L (no) 1983-04-06
DK438482A (da) 1983-04-06
FI823360A7 (fi) 1983-04-06
FI823360L (fi) 1983-04-06
PT75636A (en) 1982-11-01
ES516184A0 (es) 1983-10-01
FI823360A0 (fi) 1982-10-01
GR76712B (es) 1984-08-29
ZA826924B (en) 1983-08-31
EP0076669A1 (en) 1983-04-13
PT75636B (en) 1985-01-11
AU8898282A (en) 1983-04-14

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001