ES8401053A1 - "procedimiento de preparar benzopiranos 7-substituidos y similares". - Google Patents

"procedimiento de preparar benzopiranos 7-substituidos y similares".

Info

Publication number
ES8401053A1
ES8401053A1 ES514678A ES514678A ES8401053A1 ES 8401053 A1 ES8401053 A1 ES 8401053A1 ES 514678 A ES514678 A ES 514678A ES 514678 A ES514678 A ES 514678A ES 8401053 A1 ES8401053 A1 ES 8401053A1
Authority
ES
Spain
Prior art keywords
hydrogen
alkyl
represent
carbon atoms
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514678A
Other languages
English (en)
Other versions
ES514678A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of ES514678A0 publication Critical patent/ES514678A0/es
Publication of ES8401053A1 publication Critical patent/ES8401053A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE PREPARAR BENZOPIRANOS 7-SUSTITUIDOS Y SIMILARES.SE HACE REACCIONAR EL COMPUESTO (II) CON EL COMPUESTO CARBONILO (III) EN EL QUE R9 ES HIDROGENO O ALQUILO C1-6; R10 ES HIDROGENO, ALQUILO C1-5, HIDROXIALQUILO (1-3 O ALQUENILO C2-3, DIALCOXI C1-4) FENIL (ALQUILO C1-3), CON SEPARACION SIMULTANEA DE AGUA PARA POSTERIORMENTE REDUCIR LA BASE DE SCHIFF FORMADA. LA SEPARACION DE AGUA PUEDE FORZARSE CON CALENTAMIENTO EN UN DISOLVENTE INERTE. LA REDUCCION SE EFECTUA EMPLEANDO AGENTES TALES COMO HIDRUROS DE METALES, PREFERENTEMENTE TETRAHIDROBORATO SODICO;COMO CATALIZADOR SE EMPLEA PLATINO O NIQUEL RANEY O BIEN PALADIO SOBRE CARBON. SE OBTIENE EL COMPUESTO (I).
ES514678A 1980-12-16 1982-07-16 "procedimiento de preparar benzopiranos 7-substituidos y similares". Expired ES8401053A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU803001A HU184359B (en) 1980-12-16 1980-12-16 Process for preparing substituted acyl-carbamides

Publications (2)

Publication Number Publication Date
ES514678A0 ES514678A0 (es) 1983-12-16
ES8401053A1 true ES8401053A1 (es) 1983-12-16

Family

ID=10962081

Family Applications (2)

Application Number Title Priority Date Filing Date
ES504419A Expired ES8301958A1 (es) 1980-12-16 1981-07-17 Procedimiento de preparar benzopiranos 7-substituidos
ES514678A Expired ES8401053A1 (es) 1980-12-16 1982-07-16 "procedimiento de preparar benzopiranos 7-substituidos y similares".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES504419A Expired ES8301958A1 (es) 1980-12-16 1981-07-17 Procedimiento de preparar benzopiranos 7-substituidos

Country Status (20)

Country Link
US (1) US4391821A (es)
JP (1) JPS57109780A (es)
AU (1) AU7308781A (es)
BE (1) BE889665A (es)
DD (1) DD201305A5 (es)
DE (1) DE3127421A1 (es)
DK (1) DK320681A (es)
ES (2) ES8301958A1 (es)
FI (1) FI812215A7 (es)
FR (1) FR2496102A1 (es)
GB (1) GB2089338B (es)
GR (1) GR74595B (es)
HU (1) HU184359B (es)
IL (1) IL63267A0 (es)
NL (1) NL8103403A (es)
NO (1) NO812466L (es)
PL (2) PL237708A1 (es)
PT (1) PT73395B (es)
SE (1) SE8104435L (es)
YU (1) YU177181A (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668804A (en) * 1981-05-01 1987-05-26 Pennwalt Corporation Chromones
US4668805A (en) * 1981-05-01 1987-05-26 Pennwalt Corporation Chromones
US4501755A (en) * 1981-05-01 1985-02-26 Pennwalt Corporation Isoflavones useful as anti-inflammatory agents
US4495198A (en) * 1981-05-01 1985-01-22 Pennwalt Corporation Antihypertensive chromonoxypropanolamines
AU548450B2 (en) * 1983-08-08 1985-12-12 G.D. Searle & Co. Substituted dihydrobenzopyrans
US4678787A (en) * 1985-01-30 1987-07-07 Warner-Lambert Company 4H-1-benzopyran-4-ones and their sulfur containing analogs
US4758678A (en) * 1986-07-18 1988-07-19 Pennwalt Corporation Preparation of 7-(2,3-epoxypropoxy)flavone
US4797498A (en) * 1986-07-18 1989-01-10 Pennwalt Corporation Flavonoxypropanolamines and esters of flavonoxypropanolamines as antiarrhythmic agents
US4889941A (en) * 1987-04-23 1989-12-26 Fisons Corporation Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase
US4971982A (en) * 1987-07-06 1990-11-20 Hoffmann-La Roche Inc. Benzopyran derivatives
US4806660A (en) * 1987-11-06 1989-02-21 Pennwalt Corporation Aurone oxypropanolamines
JP2779240B2 (ja) * 1987-12-11 1998-07-23 三井化学株式会社 新規アミン類およびその用途
US5093353A (en) * 1988-05-20 1992-03-03 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US5219883A (en) * 1988-05-20 1993-06-15 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US4950684A (en) * 1988-05-20 1990-08-21 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US20010018446A1 (en) 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
JP2007008822A (ja) * 2005-06-28 2007-01-18 Tokuyama Corp ジヒドロベンゾピラン誘導体の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046275A (en) * 1958-05-30 1962-07-24 Chemiewerk Homburg Zweignieder N-substituted 2-phenyl-7-aminoalkoxy chromones
DE2123923A1 (de) * 1971-05-14 1972-11-23 Boehringer Mannheim Gmbh, 6800 Mannheim 4-eckige Klammer auf omega- (Flavon-7yl-oxy) -alkyl eckige Klammer zu -pigerazin-Derivate und Verfahren zu ihrer Herstellung
GB1493998A (en) * 1975-06-03 1977-12-07 Beecham Group Ltd Propanolamine derivatives
EP0017352A3 (en) * 1979-03-24 1981-01-07 Beecham Group Plc Chromanone derivatives, a process for their preparation, compositions containing them

Also Published As

Publication number Publication date
BE889665A (fr) 1981-11-16
PL237708A1 (en) 1983-06-20
ES514678A0 (es) 1983-12-16
PT73395B (en) 1982-10-01
PT73395A (pt) 1981-08-01
DE3127421A1 (de) 1982-08-19
FR2496102A1 (fr) 1982-06-18
PL232234A1 (en) 1983-06-06
ES504419A0 (es) 1983-01-01
GR74595B (es) 1984-06-29
FI812215L (fi) 1982-06-17
JPS57109780A (en) 1982-07-08
YU177181A (en) 1983-10-31
ES8301958A1 (es) 1983-01-01
SE8104435L (sv) 1982-06-17
NL8103403A (nl) 1982-07-16
DK320681A (da) 1982-06-17
GB2089338A (en) 1982-06-23
DD201305A5 (de) 1983-07-13
US4391821A (en) 1983-07-05
NO812466L (no) 1982-06-17
HU184359B (en) 1984-08-28
FI812215A7 (fi) 1982-06-17
IL63267A0 (en) 1981-10-30
GB2089338B (en) 1984-02-22
AU7308781A (en) 1982-06-24

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