ES8401057A1 - Procedimiento para preparar derivados de piridazinona. - Google Patents
Procedimiento para preparar derivados de piridazinona.Info
- Publication number
- ES8401057A1 ES8401057A1 ES517334A ES517334A ES8401057A1 ES 8401057 A1 ES8401057 A1 ES 8401057A1 ES 517334 A ES517334 A ES 517334A ES 517334 A ES517334 A ES 517334A ES 8401057 A1 ES8401057 A1 ES 8401057A1
- Authority
- ES
- Spain
- Prior art keywords
- alcoxy
- alkyl
- compound
- formula
- substitute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Detergent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE PIRIDAZINONA.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), DON DE PY ES UN GRUPO 2-,3-, O 4-PIRIDILO QUE ESTA INSUSTITUIDO O QUE LLEVA UNO O DOS SUSTITUYENTES ELEGIDOS ENTRE HALOGENO, CIANO, HIDROXIMETILO, CARBOXI, CARBAMOILO Y ALQUILO, ALCOXI, ALCOXI-CARBONILO, ALQUILCARBAMOILO Y DIALQUILCARBAMOILO EN DONDE CADA ALQUILO O ALCOXI TIENE HASTA 4 ATOMOS DE CARBONO, O QUE LLEVA UN SUSTITUYENTE OXIGENO BIEN COMO UN N-OXIDO O COMO UN SUSTITUYENTE OXO, EN EL ATOMO DE CARBONO 2 O 4; O UNA SALDE ADICION DE ACIDO DEL MISMO; CON HIDRAZINA, PREFERIBLEMENTE, EN UN DISOLVENTE, TAL COMO METANOL, A LA TEMPERATURA DE LABORATORIO, PARA DAR UN COMPUESTO DE FORMULA (I), DONDE PY TIENE EL MISMO SIGNIFICADO QUE EN (II).DE APLICACION FARMACOLOGICA POR SUS PROPIEDADES CARDIOTONICAS Y/O ANTIHIPERTENSIVAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8134177 | 1981-11-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8401057A1 true ES8401057A1 (es) | 1983-12-01 |
| ES517334A0 ES517334A0 (es) | 1983-12-01 |
Family
ID=10525838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES517334A Granted ES517334A0 (es) | 1981-11-12 | 1982-11-12 | Procedimiento para preparar derivados de piridazinona. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4508721A (es) |
| EP (1) | EP0081906B1 (es) |
| JP (1) | JPS5890581A (es) |
| AT (1) | ATE14430T1 (es) |
| AU (1) | AU555858B2 (es) |
| CA (1) | CA1189862A (es) |
| DE (1) | DE3264939D1 (es) |
| DK (1) | DK483282A (es) |
| ES (1) | ES517334A0 (es) |
| FI (1) | FI73991C (es) |
| GR (1) | GR77366B (es) |
| HU (1) | HU188221B (es) |
| IE (1) | IE54598B1 (es) |
| IL (1) | IL67184A (es) |
| MY (1) | MY8700460A (es) |
| NO (1) | NO159489C (es) |
| NZ (1) | NZ202473A (es) |
| PT (1) | PT75826B (es) |
| YU (1) | YU292882A (es) |
| ZA (1) | ZA827724B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3321012A1 (de) * | 1983-06-10 | 1984-12-13 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 4,5-dihydro-6-(thien-2-yl)-3(2h)-pyridazinone und 6-(thien-2-yl)-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung |
| GB8323553D0 (en) * | 1983-09-02 | 1983-10-05 | Smith Kline French Lab | Pharmaceutical compositions |
| JPS60126282A (ja) * | 1983-12-14 | 1985-07-05 | Mitsubishi Chem Ind Ltd | ピリダジノン誘導体又はその塩類 |
| JPS60197672A (ja) * | 1984-03-16 | 1985-10-07 | Mitsubishi Chem Ind Ltd | ビリダジノン誘導体またはその塩類 |
| US4631279A (en) * | 1984-10-15 | 1986-12-23 | Eli Lilly And Company | 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents |
| US4656170A (en) * | 1985-05-28 | 1987-04-07 | Warner-Lambert Company | N-[4-[2-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)ethenyl]phenyl]acetamide and related compounds |
| EP0597556B1 (en) * | 1985-12-13 | 2001-10-17 | Canon Kabushiki Kaisha | Image processing apparatus |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4304777A (en) * | 1979-08-30 | 1981-12-08 | Sterling Drug Inc. | 6-(Pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics |
| US4298609A (en) * | 1979-08-30 | 1981-11-03 | Sterling Drug Inc. | 4,5-Dihydro-6-(4-pyridinyl)-3-pyridazinol and salts, their preparation and use as blood pressure lowering agents |
| US4346221A (en) * | 1980-04-28 | 1982-08-24 | Sterling Drug Inc. | Preparation of 4-amino-6-(pyridinyl)-3(2H)-pyridazinones from 6-(pyridinyl)-3(2H)-pyridazinones |
-
1982
- 1982-10-15 IE IE2496/82A patent/IE54598B1/en unknown
- 1982-10-21 ZA ZA827724A patent/ZA827724B/xx unknown
- 1982-10-22 CA CA000414001A patent/CA1189862A/en not_active Expired
- 1982-10-28 AU AU89872/82A patent/AU555858B2/en not_active Ceased
- 1982-11-01 DK DK483282A patent/DK483282A/da not_active Application Discontinuation
- 1982-11-03 US US06/438,729 patent/US4508721A/en not_active Expired - Fee Related
- 1982-11-04 EP EP82305868A patent/EP0081906B1/en not_active Expired
- 1982-11-04 DE DE8282305868T patent/DE3264939D1/de not_active Expired
- 1982-11-04 AT AT82305868T patent/ATE14430T1/de not_active IP Right Cessation
- 1982-11-05 IL IL67184A patent/IL67184A/xx unknown
- 1982-11-09 GR GR69765A patent/GR77366B/el unknown
- 1982-11-10 PT PT75826A patent/PT75826B/pt unknown
- 1982-11-10 HU HU823610A patent/HU188221B/hu not_active IP Right Cessation
- 1982-11-11 NZ NZ202473A patent/NZ202473A/en unknown
- 1982-11-11 NO NO823766A patent/NO159489C/no unknown
- 1982-11-12 ES ES517334A patent/ES517334A0/es active Granted
- 1982-11-12 FI FI823896A patent/FI73991C/fi not_active IP Right Cessation
- 1982-11-12 JP JP57197840A patent/JPS5890581A/ja active Pending
- 1982-12-31 YU YU02928/82A patent/YU292882A/xx unknown
-
1987
- 1987-12-30 MY MY460/87A patent/MY8700460A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0081906A1 (en) | 1983-06-22 |
| NO159489C (no) | 1989-01-04 |
| US4508721A (en) | 1985-04-02 |
| HU188221B (en) | 1986-03-28 |
| IE54598B1 (en) | 1989-12-06 |
| DK483282A (da) | 1983-05-13 |
| PT75826A (en) | 1982-12-01 |
| IL67184A (en) | 1986-08-31 |
| FI823896L (fi) | 1983-05-13 |
| IE822496L (en) | 1983-05-12 |
| FI73991C (fi) | 1987-12-10 |
| AU8987282A (en) | 1983-05-19 |
| ES517334A0 (es) | 1983-12-01 |
| GR77366B (es) | 1984-09-11 |
| JPS5890581A (ja) | 1983-05-30 |
| FI73991B (fi) | 1987-08-31 |
| YU292882A (en) | 1985-04-30 |
| PT75826B (en) | 1985-11-12 |
| NO159489B (no) | 1988-09-26 |
| NO823766L (no) | 1983-05-13 |
| NZ202473A (en) | 1985-05-31 |
| MY8700460A (en) | 1987-12-31 |
| EP0081906B1 (en) | 1985-07-24 |
| ZA827724B (en) | 1983-10-26 |
| AU555858B2 (en) | 1986-10-09 |
| CA1189862A (en) | 1985-07-02 |
| FI823896A0 (fi) | 1982-11-12 |
| DE3264939D1 (en) | 1985-08-29 |
| ATE14430T1 (de) | 1985-08-15 |
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