ES8401092A1 - "proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b". - Google Patents

"proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b".

Info

Publication number
ES8401092A1
ES8401092A1 ES514620A ES514620A ES8401092A1 ES 8401092 A1 ES8401092 A1 ES 8401092A1 ES 514620 A ES514620 A ES 514620A ES 514620 A ES514620 A ES 514620A ES 8401092 A1 ES8401092 A1 ES 8401092A1
Authority
ES
Spain
Prior art keywords
methylkanamycin
amino
production
tridesoxy
tridesoxi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514620A
Other languages
English (en)
Other versions
ES514620A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55109854A external-priority patent/JPS5753496A/ja
Priority claimed from JP56058389A external-priority patent/JPS57175198A/ja
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of ES8401092A1 publication Critical patent/ES8401092A1/es
Publication of ES514620A0 publication Critical patent/ES514620A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCESO PARA LA PRODUCCION DE UNA 1-N-(-HIDROXI-AMINOALCA NOIL)-5,3,4-TRIDESOXI-6-N-METILKANAMICINA B.SE EFECTUAN LAS SIGUIENTES ETAPAS: 1) ACILACION DEL GRUPO 1-AMINO DE LAS 5,3, 4-TRIDESOXI-6-N-METILKANAMICINA B O BIEN UN DERIVADO PARCIALMENTE AMINO-PROTEGIDO DE 5,3,4-TRIDESOXI-6-N-METILKANAMICINA B POR REACCION CON UN ACIDO -HIDROXI-AMINOALCANOICO O UN DERIVADO AMINO-PROTEGIDO DEL MISMO; SE PRODUCE EL DERIVADO 1-N-ACILADO CORRESPONDIENTE. 2) RETIRADA DEL O DE LOS GRUPOS AMINO-PROTECTORES RESTANTES CUANDO EXISTEN DEL PRODUCTO 1-N-ACILADO DE MANERA CONOCIDA. SE OBTIENE EL COMPUESTO (I) EN QUE N ES UN NUMEROENTERO ENTRE 1, 2 O 3.
ES514620A 1980-08-12 1982-07-31 "proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b". Granted ES514620A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55109854A JPS5753496A (en) 1980-08-12 1980-08-12 1-n-acyl derivative of 5,3',4'-trideoxykanamycin b or 5,3',4',6'- tetradeoxykanamycin b, and their preparation
JP56058389A JPS57175198A (en) 1981-04-20 1981-04-20 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation

Publications (2)

Publication Number Publication Date
ES8401092A1 true ES8401092A1 (es) 1983-12-16
ES514620A0 ES514620A0 (es) 1983-12-16

Family

ID=26399440

Family Applications (4)

Application Number Title Priority Date Filing Date
ES504697A Expired ES8301486A1 (es) 1980-08-12 1981-08-11 Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos
ES514622A Expired ES8308334A1 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4'-tridesoxi-6'-n-metilkanamicina b".
ES514621A Granted ES514621A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b".
ES514620A Granted ES514620A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b".

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES504697A Expired ES8301486A1 (es) 1980-08-12 1981-08-11 Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos
ES514622A Expired ES8308334A1 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4'-tridesoxi-6'-n-metilkanamicina b".
ES514621A Granted ES514621A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b".

Country Status (9)

Country Link
KR (1) KR850000979B1 (es)
CA (1) CA1175816A (es)
CH (1) CH648564A5 (es)
DE (1) DE3131731C2 (es)
ES (4) ES8301486A1 (es)
FR (1) FR2491073A1 (es)
GB (1) GB2082575B (es)
IT (1) IT1167959B (es)
NL (1) NL8103639A (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS554118B2 (es) * 1973-08-29 1980-01-29

Also Published As

Publication number Publication date
CH648564A5 (de) 1985-03-29
KR850000979B1 (ko) 1985-07-05
NL8103639A (nl) 1982-03-01
ES8401093A1 (es) 1983-12-16
CA1175816A (en) 1984-10-09
GB2082575A (en) 1982-03-10
ES514622A0 (es) 1983-08-16
FR2491073A1 (fr) 1982-04-02
ES504697A0 (es) 1982-12-01
DE3131731C2 (de) 1984-02-16
ES8301486A1 (es) 1982-12-01
FR2491073B1 (es) 1984-08-03
ES514620A0 (es) 1983-12-16
DE3131731A1 (de) 1982-03-11
IT1167959B (it) 1987-05-20
KR830006325A (ko) 1983-09-24
ES514621A0 (es) 1983-12-16
GB2082575B (en) 1984-04-18
IT8109493A0 (it) 1981-08-07
ES8308334A1 (es) 1983-08-16

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