ES8401094A1 - A procedure for the production of 1-b-d-arabinofuranosil-5- (2-carboxivinil) uracil or its derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the production of 1-b-d-arabinofuranosil-5- (2-carboxivinil) uracil or its derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8401094A1 ES8401094A1 ES516308A ES516308A ES8401094A1 ES 8401094 A1 ES8401094 A1 ES 8401094A1 ES 516308 A ES516308 A ES 516308A ES 516308 A ES516308 A ES 516308A ES 8401094 A1 ES8401094 A1 ES 8401094A1
- Authority
- ES
- Spain
- Prior art keywords
- arabinofuranosil
- carboxivinil
- translation
- derivatives
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940035893 uracil Drugs 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 230000001681 protective effect Effects 0.000 abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical class [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDURE FOR THE OBTAINING OF 1-B-D-ARABINOFURANOSIL -5- (2-CARBOXIVINIL) URACILO AND ITS DERIVATIVES, IN FORMULA (I), IN WHICH R1, R2 AND R3 ARE HYDROGEN OR A NUCLEOXID HYDROXYL PROTECTIVE GROUP; AND R4 IS HYDROGEN OR ALKYL. IT CONSISTS IN THE REACTION OF A 1-BD-ARABINOFURANOSIL-5-HALOGENOURACIL, OF FORMULA (II), IN WHICH R1, R2 AND R3 ARE PROTECTIVE GROUPS AND X IS A HALOGEN, WITH AN ALKYL ACRYLATE . THE REACTION IS CARRIED OUT IN A POLAR SOLVENT, IN THE PRESENCE OF A TERTIARY AMINE, A PHOSPHINE, AND A PALADIUM CATALYST. THESE COMPOUNDS HAVE APPLICATIONS AS INTERMEDIATES IN ORGANIC SYNTHESIS. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56161152A JPS5862194A (en) | 1981-10-08 | 1981-10-08 | 1-beta-d-arabinofuranosyl-(e)-5-(2-carboxyvinyl)uracil or its derivative and their preparation |
| JP56161153A JPS5862195A (en) | 1981-10-08 | 1981-10-08 | Production of 1-beta-d-arabinofuranosyl-(e)-5-(2- halogenovinyl)uracil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8401094A1 true ES8401094A1 (en) | 1983-11-16 |
| ES516308A0 ES516308A0 (en) | 1983-11-16 |
Family
ID=26487389
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES516308A Granted ES516308A0 (en) | 1981-10-08 | 1982-10-07 | A PROCEDURE FOR THE PRODUCTION OF 1-B-D-ARABINOFURANOSIL-5- (2-CARBOXIVINIL) URACILO OR ITS DERIVATIVES. |
| ES524030A Granted ES524030A0 (en) | 1981-10-08 | 1983-07-11 | A PROCEDURE FOR THE PRODUCTION OF A 1-BETA-D-ARABINOFURANOSIL- (E) -5- (2-HALOGENOVINIL) URACILO. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES524030A Granted ES524030A0 (en) | 1981-10-08 | 1983-07-11 | A PROCEDURE FOR THE PRODUCTION OF A 1-BETA-D-ARABINOFURANOSIL- (E) -5- (2-HALOGENOVINIL) URACILO. |
Country Status (2)
| Country | Link |
|---|---|
| CA (1) | CA1204108A (en) |
| ES (2) | ES516308A0 (en) |
-
1982
- 1982-10-07 ES ES516308A patent/ES516308A0/en active Granted
- 1982-10-08 CA CA000413099A patent/CA1204108A/en not_active Expired
-
1983
- 1983-07-11 ES ES524030A patent/ES524030A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8502127A1 (en) | 1984-12-16 |
| CA1204108A (en) | 1986-05-06 |
| ES516308A0 (en) | 1983-11-16 |
| ES524030A0 (en) | 1984-12-16 |
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