ES8403106A1 - Procedimiento para la preparacion de 3-(10,11-dihidro-5h-dibenzo-a,d-ciclohepten-5-iliden-n,n-dimetil-1-propanamin-n-o- xido dihidratado. - Google Patents
Procedimiento para la preparacion de 3-(10,11-dihidro-5h-dibenzo-a,d-ciclohepten-5-iliden-n,n-dimetil-1-propanamin-n-o- xido dihidratado.Info
- Publication number
- ES8403106A1 ES8403106A1 ES522311A ES522311A ES8403106A1 ES 8403106 A1 ES8403106 A1 ES 8403106A1 ES 522311 A ES522311 A ES 522311A ES 522311 A ES522311 A ES 522311A ES 8403106 A1 ES8403106 A1 ES 8403106A1
- Authority
- ES
- Spain
- Prior art keywords
- cyclohepten
- ylidene
- dibenzo
- dihydro
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- ZPMKQFOGINQDAM-UHFFFAOYSA-N amitriptylinoxide Chemical compound C1CC2=CC=CC=C2C(=CCC[N+](C)([O-])C)C2=CC=CC=C21 ZPMKQFOGINQDAM-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XCCXBFSUKGXNDY-UHFFFAOYSA-N 3-(5,6-dihydrodibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-n,n-dimethylpropan-1-amine oxide;dihydrate Chemical compound O.O.C1CC2=CC=CC=C2C(=CCC[N+](C)([O-])C)C2=CC=CC=C21 XCCXBFSUKGXNDY-UHFFFAOYSA-N 0.000 abstract 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- KRMDCWKBEZIMAB-UHFFFAOYSA-N amitriptyline Chemical compound C1CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 KRMDCWKBEZIMAB-UHFFFAOYSA-N 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
- C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE 3-(10,11-DIHIDRO-5H-DIBENZOA,D-CICLOHEPTEN-5-ILIDEN)-N,N- DIMETIL-1-PROPANAMIN-N-OXIDO DIHIDRATADO, SUS SALES POR ADICION DE ACIDOS.CONSISTE EN HACER REACCIONAR 3-(10,11-DIHIDRO-5H-DIBENZOA,D-CICLOH EPTEN-5-ILIDEN)-N,N-DIMETIL-1-PROPANAMINA, CON UNA SOLUCION DE PEROXIDO DE HIDROGENO AL 25-85 DURANTE UN TIEMPO COMPRENDIDO ENTRE 20 MINUTOS Y 4 HORAS. EL N-OXIDO OBTENIDO SE AISLA COMO TAL O COMO SAL POR ADICION DE ACIDO, A PARTIR DE LA MEZCLA DE REACCION.DE APLICACION EN EL TRATAMIENTO DE DEPRESIONES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3218026A DE3218026C2 (de) | 1982-05-13 | 1982-05-13 | Verfahren zur Herstellung von 3-(10,11-Dihydro-5H-dibenzo[a,d]-cyclohepten-5-yliden)-N,N-dimethyl-1-propanamin-N-oxid- Dihydrat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8403106A1 true ES8403106A1 (es) | 1984-03-01 |
| ES522311A0 ES522311A0 (es) | 1984-03-01 |
Family
ID=6163494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522311A Granted ES522311A0 (es) | 1982-05-13 | 1983-05-12 | Procedimiento para la preparacion de 3-(10,11-dihidro-5h-dibenzo-a,d-ciclohepten-5-iliden-n,n-dimetil-1-propanamin-n-o- xido dihidratado. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0094560B1 (es) |
| AT (1) | ATE22437T1 (es) |
| DE (2) | DE3218026C2 (es) |
| DK (1) | DK211983A (es) |
| ES (1) | ES522311A0 (es) |
| IE (1) | IE55158B1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693861A (en) * | 1991-08-05 | 1997-12-02 | Albemarle Corporation | Process for preparing solid amine oxides |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3215741A (en) * | 1963-01-08 | 1965-11-02 | Du Pont | Process for preparing maine oxides |
| GB991651A (en) * | 1963-02-20 | 1965-05-12 | Dumex Ltd As | Dibenzocycloheptadiene derivatives |
| BR6572744D0 (pt) * | 1964-09-14 | 1973-08-07 | Merck & Co Inc | Processo para preparacao de novos derivados dibenzocicloheptenicos |
| DE1518104B1 (de) * | 1965-05-21 | 1970-05-14 | Pennsalt Chemicals Corp | Verfahren zur Herstellung von tertiaeren Aminoxyden |
| US3432555A (en) * | 1967-04-05 | 1969-03-11 | Millmaster Onyx Corp | Process for producing amine oxides |
| GB1538199A (en) * | 1974-12-19 | 1979-01-10 | Albright & Wilson | Preparation of amine oxides |
-
1982
- 1982-05-13 DE DE3218026A patent/DE3218026C2/de not_active Expired
-
1983
- 1983-05-05 AT AT83104407T patent/ATE22437T1/de not_active IP Right Cessation
- 1983-05-05 EP EP83104407A patent/EP0094560B1/de not_active Expired
- 1983-05-05 DE DE8383104407T patent/DE3366400D1/de not_active Expired
- 1983-05-10 IE IE1080/83A patent/IE55158B1/en not_active IP Right Cessation
- 1983-05-11 DK DK211983A patent/DK211983A/da not_active Application Discontinuation
- 1983-05-12 ES ES522311A patent/ES522311A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0094560B1 (de) | 1986-09-24 |
| IE55158B1 (en) | 1990-06-20 |
| DK211983D0 (da) | 1983-05-11 |
| ATE22437T1 (de) | 1986-10-15 |
| DE3218026A1 (de) | 1983-12-15 |
| EP0094560A1 (de) | 1983-11-23 |
| IE831080L (en) | 1983-11-13 |
| DE3366400D1 (en) | 1986-10-30 |
| ES522311A0 (es) | 1984-03-01 |
| DE3218026C2 (de) | 1984-03-29 |
| DK211983A (da) | 1983-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |