ES8500221A1 - Procedimiento para preparar derivados de guanidina. - Google Patents

Procedimiento para preparar derivados de guanidina.

Info

Publication number
ES8500221A1
ES8500221A1 ES510584A ES510584A ES8500221A1 ES 8500221 A1 ES8500221 A1 ES 8500221A1 ES 510584 A ES510584 A ES 510584A ES 510584 A ES510584 A ES 510584A ES 8500221 A1 ES8500221 A1 ES 8500221A1
Authority
ES
Spain
Prior art keywords
formula
compound
bicyclic derivatives
butoxide
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510584A
Other languages
English (en)
Other versions
ES510584A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES510584A0 publication Critical patent/ES510584A0/es
Publication of ES8500221A1 publication Critical patent/ES8500221A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE GUANIDINA, DE FORMULA GENERAL (I), Y DE SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III) A TEMPERATURA AMBIENTE Y EN PRESENCIA DE T-BUTOXIDO DE POTASIO. EL PRODUCTO OBTENIDO SE HACE REACCIONAR CON NIQUEL RANEY EN ETANOL BAJO REFLUJO.DE APLICACION EN EL TRATAMIENTO DE ULCERAS PEPTICAS.
ES510584A 1981-03-18 1982-03-18 Procedimiento para preparar derivados de guanidina. Expired ES8500221A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8108408 1981-03-18
GB8124152 1981-08-07

Publications (2)

Publication Number Publication Date
ES510584A0 ES510584A0 (es) 1984-10-01
ES8500221A1 true ES8500221A1 (es) 1984-10-01

Family

ID=26278796

Family Applications (1)

Application Number Title Priority Date Filing Date
ES510584A Expired ES8500221A1 (es) 1981-03-18 1982-03-18 Procedimiento para preparar derivados de guanidina.

Country Status (9)

Country Link
EP (1) EP0060730A3 (es)
AU (1) AU562654B2 (es)
CA (1) CA1200812A (es)
DK (1) DK121682A (es)
ES (1) ES8500221A1 (es)
FI (1) FI820936L (es)
NO (1) NO820889L (es)
NZ (1) NZ200048A (es)
PT (1) PT74604B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives
US4644006A (en) * 1984-06-22 1987-02-17 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US4692531A (en) * 1984-06-22 1987-09-08 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US5001138B1 (en) * 1985-02-04 1998-01-20 Bayer Agrochem Kk Heterocyclic compounds
DE3681465D1 (es) * 1985-02-04 1991-10-24 Nihon Bayer Agrochem K.K., Tokio/Tokyo, Jp
WO1994026715A1 (en) * 1993-05-11 1994-11-24 Smithkline Beecham Plc Amidine derivatives as gastric acid secretion inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2932643A (en) * 1960-04-12 Guanidine salts of barbituric acids
GR71929B (es) * 1979-11-13 1983-08-19 Ici Ltd

Also Published As

Publication number Publication date
EP0060730A2 (en) 1982-09-22
DK121682A (da) 1982-09-19
EP0060730A3 (en) 1982-12-08
ES510584A0 (es) 1984-10-01
AU562654B2 (en) 1987-06-18
FI820936A7 (fi) 1982-09-19
AU8168582A (en) 1982-09-23
NZ200048A (en) 1985-08-16
FI820936L (fi) 1982-09-19
PT74604A (en) 1982-04-01
PT74604B (en) 1983-11-07
CA1200812A (en) 1986-02-18
NO820889L (no) 1982-09-20

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