ES8501628A1 - Procedimiento para la fabricacion de nuevos productos a partir del factor timico del suero, de sus analogos y derivados. - Google Patents

Procedimiento para la fabricacion de nuevos productos a partir del factor timico del suero, de sus analogos y derivados.

Info

Publication number
ES8501628A1
ES8501628A1 ES518298A ES518298A ES8501628A1 ES 8501628 A1 ES8501628 A1 ES 8501628A1 ES 518298 A ES518298 A ES 518298A ES 518298 A ES518298 A ES 518298A ES 8501628 A1 ES8501628 A1 ES 8501628A1
Authority
ES
Spain
Prior art keywords
analogs
derivatives
tsf
metal
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518298A
Other languages
English (en)
Other versions
ES518298A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Santé et de la Recherche Médicale
Original Assignee
Institut National de la Santé et de la Recherche Médicale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Santé et de la Recherche Médicale filed Critical Institut National de la Santé et de la Recherche Médicale
Publication of ES8501628A1 publication Critical patent/ES8501628A1/es
Publication of ES518298A0 publication Critical patent/ES518298A0/es
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/062—Serum thymic factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA FABRICACION DE NUEVOS PRODUCTOS A PARTIR DEL FACTOR TIMICO DEL SUERO, DE SUS ANALOGOS Y DERIVADOS.CONSISTE EN TRATAR EL FACTOR TIMICO DEL SUERO O UNO DE SUS ANALOGOS O DERIVADOS CON UN METAL BIVALENTE O TRIVALENTE COMO ZINC, O CON UNA SUSTANCIA PROTEICA QUE ES UNA FRACCION DE EXTRACTO TIMICO, PREPARANDO A CONTINUACION UN TRAZADOR QUE COMPRENDE EL PRODUCTO MARCADO POR UN ISOTOPO RADIOACTIVO MEDIANTE LA INTRODUCCION PREVIA DE UNA MOLECULA YODABLE PARA EL PRODUCTO, PROCEDIENDO LUEGO AL YODADO DEL DERIVADO YODABLE CONSEGUIDO. EL FACTOR DE ACIDEZ ESTA COMPRENDIDO ENTRE 7 Y 9 DURANTE 10 A 30 MINUTOS Y A TEMPERATURA AMBIENTE, UTILIZANDOSE UNA PORCION DE UN MOL DE FACTOR FTS POR CADA 0,1 A 10 MOLES DE METAL O DE UNA DE SUS SALES.
ES518298A 1980-05-22 1982-12-16 Procedimiento para la fabricacion de nuevos productos a partir del factor timico del suero, de sus analogos y derivados. Granted ES518298A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8017027 1980-05-22
GB8030507 1980-09-22

Publications (2)

Publication Number Publication Date
ES8501628A1 true ES8501628A1 (es) 1984-12-16
ES518298A0 ES518298A0 (es) 1984-12-16

Family

ID=26275622

Family Applications (2)

Application Number Title Priority Date Filing Date
ES502911A Granted ES502911A0 (es) 1980-05-22 1981-05-22 Procedimiento para la preparacion de productos derivados delfactor timico del suero (fts),de sus analogos y derivados
ES518298A Granted ES518298A0 (es) 1980-05-22 1982-12-16 Procedimiento para la fabricacion de nuevos productos a partir del factor timico del suero, de sus analogos y derivados.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES502911A Granted ES502911A0 (es) 1980-05-22 1981-05-22 Procedimiento para la preparacion de productos derivados delfactor timico del suero (fts),de sus analogos y derivados

Country Status (8)

Country Link
EP (1) EP0041019B1 (es)
AU (1) AU553640B2 (es)
CA (1) CA1170991A (es)
DE (1) DE3166925D1 (es)
DK (1) DK221681A (es)
ES (2) ES502911A0 (es)
GR (1) GR75636B (es)
IE (1) IE51744B1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634682A (en) * 1982-11-30 1987-01-06 Sloan-Kettering Institute For Cancer Radioimmunoassays for the serum thymic factor (FTS)
CS256897B1 (en) * 1984-12-17 1988-04-15 Evzen Kasafirek Series thymic factor's analogue-type peptides
IT1188550B (it) * 1986-02-07 1988-01-14 Sclavo Spa Peptide sintetico ad attivita' interleukina 1 umana
FR2830451B1 (fr) * 2001-10-09 2004-04-30 Inst Nat Sante Rech Med Utilisation de peptides analogues de la thymuline(pat)pour la fabrication de medicaments contre la douleur
JP5296667B2 (ja) 2006-03-20 2013-09-25 スミス アンド ネフュー インコーポレーテッド 多数のベアリング要素のための寛骨臼カップ組立体
FR2930156B1 (fr) * 2008-04-21 2011-10-28 Cll Pharma Utilisation du nonapeptide pat dans le traitement des maladies autoimmunes.
EP4013769A4 (en) * 2019-08-15 2024-01-03 Cytolyf Therapeutics LLC ZINC-ACTIVATED THYMULINE AND METHOD FOR PREPARATION AND ADMINISTRATION

Also Published As

Publication number Publication date
EP0041019B1 (fr) 1984-10-31
AU7090581A (en) 1981-11-26
ES8306022A1 (es) 1983-05-01
IE811135L (en) 1981-11-22
ES502911A0 (es) 1983-05-01
IE51744B1 (en) 1987-03-18
GR75636B (es) 1984-08-02
AU553640B2 (en) 1986-07-24
EP0041019A3 (en) 1982-03-10
EP0041019A2 (fr) 1981-12-02
DK221681A (da) 1981-11-23
ES518298A0 (es) 1984-12-16
CA1170991A (en) 1984-07-17
DE3166925D1 (en) 1984-12-06

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303