ES8502405A1 - Un metodo para producir una emulsion acuosa de perfluorocarburo - Google Patents

Un metodo para producir una emulsion acuosa de perfluorocarburo

Info

Publication number
ES8502405A1
ES8502405A1 ES524972A ES524972A ES8502405A1 ES 8502405 A1 ES8502405 A1 ES 8502405A1 ES 524972 A ES524972 A ES 524972A ES 524972 A ES524972 A ES 524972A ES 8502405 A1 ES8502405 A1 ES 8502405A1
Authority
ES
Spain
Prior art keywords
dispersion
perfluorocarbide
emulsion
therapy
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524972A
Other languages
English (en)
Other versions
ES524972A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunoco Inc R&M
Original Assignee
Sunoco Inc R&M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27020315&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8502405(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sunoco Inc R&M filed Critical Sunoco Inc R&M
Publication of ES8502405A1 publication Critical patent/ES8502405A1/es
Publication of ES524972A0 publication Critical patent/ES524972A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0476—Oxygenated solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

METODO PARA PRODUCIR UNA EMULSION ACUOSA DE PERFLUOROCARBURO, QUE SE UTILIZA EN UNA COMPOSICION FARMACEUTICA ACUOSA.COMPRENDE UN PROCESO DE DISPERSION EN DOS ETAPAS, EN LA PRIMERA DE LAS CUALES SE DISPERSA EL PERFLUOROCARBURO EN UNA SOLUCION ACUOSA DE DISPERSANTE PARA PRODUCIR UNA EMULSION CON TAMAN/O DE 0,5 A UN MICRON, Y EN LA SEGUNDA ETAPA LA EMULSION ASI FORMADA ES SUBSECUENTEMENTE SOMETIDA A UN PROCESO DE MAYOR DISPERSION PARA PRODUCIR UNA EMULSION CON TAMAN/OS DE MICELA COMPRENDIDOS ENTRE 0,5 Y 0,2 MICRONES.DE APLICACION EN COMPOSICIONES Y SISTEMAS QUE SIRVEN PARA SENSIBILIZAR CELULAS TUMORALES HIPOXICAS A UNA RADIACION O A CIERTOS AGENTES QUIMIOTERAPEUTICOS.
ES524972A 1982-08-17 1983-08-16 Un metodo para producir una emulsion acuosa de perfluorocarburo Granted ES524972A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40858982A 1982-08-17 1982-08-17
US51715083A 1983-07-25 1983-07-25

Publications (2)

Publication Number Publication Date
ES8502405A1 true ES8502405A1 (es) 1985-01-01
ES524972A0 ES524972A0 (es) 1985-01-01

Family

ID=27020315

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524972A Granted ES524972A0 (es) 1982-08-17 1983-08-16 Un metodo para producir una emulsion acuosa de perfluorocarburo

Country Status (19)

Country Link
EP (1) EP0105584B1 (es)
JP (1) JPS59501665A (es)
KR (1) KR890002204B1 (es)
AU (1) AU559559B2 (es)
CA (1) CA1225027A (es)
CH (1) CH665952A5 (es)
DE (2) DE3390172T1 (es)
ES (1) ES524972A0 (es)
FI (1) FI841513L (es)
GB (1) GB2134787A (es)
GR (1) GR79383B (es)
IE (1) IE55618B1 (es)
IL (1) IL69505A (es)
NL (1) NL8320264A (es)
NO (1) NO841519L (es)
PH (2) PH25492A (es)
PT (1) PT77204B (es)
SE (1) SE8402098D0 (es)
WO (1) WO1984000686A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59130813A (ja) * 1983-01-14 1984-07-27 Green Cross Corp:The 癌化学療法補助剤
JPS59130812A (ja) * 1983-01-14 1984-07-27 Green Cross Corp:The 癌化学療法補助剤
CA1257828A (en) * 1984-04-16 1989-07-25 William Mccormick Perfluoro compound dispersions containing reduced amounts of surfactant and process of preparation
US4815446A (en) * 1985-05-09 1989-03-28 Alpha Therapeutic Corporation Process for treating metastasis of cancerous tumors
US4781676A (en) * 1987-02-20 1988-11-01 Air Products And Chemicals, Inc. Interstitial administration of perfluorochemical emulsions for reoxygenation of hypoxic tumor cells
US4956390A (en) * 1987-08-25 1990-09-11 Air Products And Chemicals, Inc. Gas transport employing perfluorobutyldecalin
JP2935519B2 (ja) * 1989-08-28 1999-08-16 シーキンス，ケイ・マイケル 超音波および／またはペルフルオロカーボン液での対流を介する肺癌高熱治療
US5562608A (en) * 1989-08-28 1996-10-08 Biopulmonics, Inc. Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation
US5518731A (en) * 1990-09-27 1996-05-21 Allergan, Inc. Nonaqueous fluorinated drug delivery vehicle suspensions
US6458376B1 (en) 1990-09-27 2002-10-01 Allergan, Inc. Nonaqueous fluorinated drug delivery suspensions
FR2679150A1 (fr) * 1991-07-17 1993-01-22 Atta Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations.
AU3924193A (en) * 1992-03-19 1993-10-21 Allergan, Inc. Compositions comprising a drug delivery vehicle suspended in a nonaqueous fluorinated liquid
DE4221268C2 (de) * 1992-06-26 1997-06-12 Lancaster Group Ag Verwendung eines Dermatikums zur Unterstützung des Sauerstofftransportes in der Haut
US5643601A (en) * 1992-06-26 1997-07-01 Lancaster Group Ag Phospholipid-and fluorocarbon-containing cosmetic
DE4221256C2 (de) * 1992-06-26 1997-07-10 Lancaster Group Ag Galenische Zusammensetzung für die topische Anwendung
US5480914A (en) * 1994-05-06 1996-01-02 Allergan, Inc. Nonaqueous thixotropic drug delivery suspensions and methods of their use
DE69940738D1 (de) * 1998-07-09 2009-05-28 Curelight Medical Ltd Vorrichtung und verfahren zur wirkungsvollen hochenergetischen photodynamischen therapie von akne vulgaris und seborrhoe
US20040122492A1 (en) 1999-07-07 2004-06-24 Yoram Harth Phototherapeutic treatment of skin conditions
GB0200721D0 (en) * 2002-01-14 2002-02-27 Univ Bristol Toxicity test
RU2440158C2 (ru) * 2010-02-25 2012-01-20 Юрий Александрович Белый Способ фотодинамической терапии субъектов, страдающих злокачественными опухолями
EP2587917A4 (en) * 2010-07-01 2015-05-06 Mtm Res Llc FLUORCHEMICAL ANTIFIBROBLAST EMULSION THERAPIES

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828085A (en) * 1970-07-09 1974-08-06 Allied Chem Novel amidoamine oxides
US3823091A (en) * 1971-05-19 1974-07-09 Green Cross Corp Stable emulsion of fluorocarbon particles
US4041086A (en) * 1972-02-07 1977-08-09 Sun Ventures, Inc. Process of manufacture of flourinated alkyladamantanes
US3911138B1 (en) * 1973-02-26 1996-10-29 Childrens Hosp Medical Center Artificial blood and method for supporting oxygen transport in animals
JPS5331209B2 (es) * 1973-10-05 1978-09-01
DE2524363A1 (de) * 1975-06-02 1976-12-16 Boehringer Sohn Ingelheim Neue pharmazeutische mittel
US4105798A (en) * 1976-07-19 1978-08-08 Sun Ventures, Inc. Perfluoro polycyclic compounds for use as synthetic blood and perfusion media
JPS5331209A (en) * 1976-09-03 1978-03-24 Hitachi Ltd Small compressor cylinder for refrigerating machine and production of same
IE47132B1 (en) * 1977-08-19 1983-12-28 Roche Products Ltd Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture
JPS6033367B2 (ja) * 1978-11-24 1985-08-02 株式会社ミドリ十字 酸素運搬輸液
US4282232A (en) * 1979-04-26 1981-08-04 Research Corporation Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof
US4252827A (en) * 1979-05-23 1981-02-24 The Green Cross Corporation Oxygen-transferable fluorocarbon emulsion
DE3049665T1 (de) * 1979-06-25 1982-03-18 Suntech Use of perfluorocarbon as burn treatment
CA1181011A (en) * 1980-05-27 1985-01-15 Robert P. Geyer Perfluorinated n,n-dimethyl cyclohexylmethylamine and emulsions containing the same
GR78151B (es) * 1982-04-05 1984-09-26 Alcon Lab Inc

Also Published As

Publication number Publication date
SE8402098L (sv) 1984-04-16
AU1941383A (en) 1984-03-07
EP0105584B1 (en) 1989-01-18
WO1984000686A1 (en) 1984-03-01
CA1225027A (en) 1987-08-04
KR890002204B1 (ko) 1989-06-23
IE831925L (en) 1984-02-17
PT77204B (en) 1986-02-04
DE3390172T1 (de) 1984-11-29
FI841513A7 (fi) 1984-04-16
SE8402098D0 (sv) 1984-04-16
FI841513A0 (fi) 1984-04-16
CH665952A5 (de) 1988-06-30
JPS59501665A (ja) 1984-10-04
GB2134787A (en) 1984-08-22
NO841519L (no) 1984-04-16
IL69505A (en) 1990-03-19
KR840005660A (ko) 1984-11-15
PT77204A (en) 1983-09-01
DE3378954D1 (en) 1989-02-23
AU559559B2 (en) 1987-03-12
PH25492A (en) 1991-07-24
ES524972A0 (es) 1985-01-01
NL8320264A (nl) 1984-07-02
EP0105584A1 (en) 1984-04-18
FI841513L (fi) 1984-04-16
IL69505A0 (en) 1983-11-30
IE55618B1 (en) 1990-11-21
PH25027A (en) 1991-01-28
GR79383B (es) 1984-10-22

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603