ES8504835A3 - Phosphorinane deriv. - Google Patents
Phosphorinane deriv.Info
- Publication number
- ES8504835A3 ES8504835A3 ES526194A ES526194A ES8504835A3 ES 8504835 A3 ES8504835 A3 ES 8504835A3 ES 526194 A ES526194 A ES 526194A ES 526194 A ES526194 A ES 526194A ES 8504835 A3 ES8504835 A3 ES 8504835A3
- Authority
- ES
- Spain
- Prior art keywords
- cpd
- chloroethyl
- formula
- phosphorinane
- deriv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VXTFGYMINLXJPW-UHFFFAOYSA-N phosphinane Chemical compound C1CCPCC1 VXTFGYMINLXJPW-UHFFFAOYSA-N 0.000 title 1
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- ONRREFWJTRBDRA-UHFFFAOYSA-N 2-chloroethanamine;hydron;chloride Chemical compound [Cl-].[NH3+]CCCl ONRREFWJTRBDRA-UHFFFAOYSA-N 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
Abstract
3-(2-Chloroethyl) 2-((2-chloroethyl)amino) 1,3,2-oxaza phosphorinano-2-oxide of formula (I) is made by (a) reacting a cpd. of formula (II) with 3-halo propanol to obtain a cpd. of formula (III); (b) this is reacted with phosphorus oxychloride to obtain 2-chloro 3-(2-chloroethyl) 1,3,2-oxazaphosphorinano-2-oxide; and (c) this cpd. is reacted with 2-chloroethylamine hydrochloride to give (I).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES526194A ES526194A0 (en) | 1983-10-03 | 1983-10-03 | PROCEDURE FOR OBTAINING A COMPOUND DERIVED FROM PHOSPHORINANE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES526194A ES526194A0 (en) | 1983-10-03 | 1983-10-03 | PROCEDURE FOR OBTAINING A COMPOUND DERIVED FROM PHOSPHORINANE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8504835A3 true ES8504835A3 (en) | 1985-04-16 |
| ES526194A0 ES526194A0 (en) | 1985-04-16 |
Family
ID=8486283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526194A Granted ES526194A0 (en) | 1983-10-03 | 1983-10-03 | PROCEDURE FOR OBTAINING A COMPOUND DERIVED FROM PHOSPHORINANE |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES526194A0 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115505003B (en) * | 2022-10-08 | 2025-03-25 | 海南锦瑞制药有限公司 | Preparation method of ifosfamide and preparation method of ifosfamide for injection |
-
1983
- 1983-10-03 ES ES526194A patent/ES526194A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES526194A0 (en) | 1985-04-16 |
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