ES8507544A1 - Procedimiento para la preparacion de n-alcohil-imidazoles sustituidos con tiocetales - Google Patents

Procedimiento para la preparacion de n-alcohil-imidazoles sustituidos con tiocetales

Info

Publication number
ES8507544A1
ES8507544A1 ES526445A ES526445A ES8507544A1 ES 8507544 A1 ES8507544 A1 ES 8507544A1 ES 526445 A ES526445 A ES 526445A ES 526445 A ES526445 A ES 526445A ES 8507544 A1 ES8507544 A1 ES 8507544A1
Authority
ES
Spain
Prior art keywords
substituted
alcohyl
thioketal
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526445A
Other languages
English (en)
Other versions
ES526445A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES526445A0 publication Critical patent/ES526445A0/es
Publication of ES8507544A1 publication Critical patent/ES8507544A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE N-ALCOHIL-IMIDAZOLES SUSTITUIDOS CON TIOCETALES.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN 1,2- O 1,3-DITIOL DISOLVENTE ACIDO METANOSULFONICO, Y DURANTE 5 MINUTOS A 24 HORAS, PARA FORMAR UN COMPUESTO DE FORMULA (I); SUS BASES LIBRES Y SUS SALES DE ADICION DE ACIDO DE ACIDOS FARMACEUTICAMENTE ACEPTABLES. SIENDO: R ALCOHILO DE C 1 A 12, CICLOPENTILO, CICLOHEXILO Y OTROS; Z ES ETILENO O PROPILENO, OPCIONALMENTE SUSTITUIDO CON UN UNICO SUSTITUYENTE QUE ES ALCOHILO INFERIOR; Y A ES 1 A 3.SE UTILIZA PARA COMBATIR Y CONTROLAR HONGOS, BACTERIAS Y PROTOZOOS, Y REPRIMIR CONVULSIONES EN MAMIFEROS.
ES526445A 1982-10-13 1983-10-13 Procedimiento para la preparacion de n-alcohil-imidazoles sustituidos con tiocetales Expired ES8507544A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/434,088 US4489087A (en) 1982-10-13 1982-10-13 Spermicidal thioketal substituted N-alkyl imidazoles

Publications (2)

Publication Number Publication Date
ES526445A0 ES526445A0 (es) 1985-10-01
ES8507544A1 true ES8507544A1 (es) 1985-10-01

Family

ID=23722780

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526445A Expired ES8507544A1 (es) 1982-10-13 1983-10-13 Procedimiento para la preparacion de n-alcohil-imidazoles sustituidos con tiocetales

Country Status (9)

Country Link
US (1) US4489087A (es)
EP (1) EP0111384B1 (es)
JP (1) JPS5989668A (es)
AU (1) AU575789B2 (es)
CA (1) CA1210012A (es)
DE (1) DE3371079D1 (es)
ES (1) ES8507544A1 (es)
NZ (1) NZ205940A (es)
ZA (1) ZA837599B (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2342728A1 (fr) * 1976-03-05 1977-09-30 Anvar Procedes de preparation de derives d'heterocycles aromatiques azotes n-substitues, produits obtenus et applications
IT1160898B (it) * 1977-11-04 1987-03-11 Syntex Inc Derivati dell'1-(naftiletil)-imidazolo,particolarmente utili come anticonvulsivi ed antisecretivi,e procedimento per la loro preparazione
US4277486A (en) * 1979-03-09 1981-07-07 Syntex (U.S.A.) Inc. 1-[(Substituted-naphthyl)ethyl]-imidazole derivatives
US4483865A (en) * 1981-03-27 1984-11-20 Janssen Pharmaceutica N.V. Antimicrobial imidazole derivatives
CA1179678A (en) * 1981-03-27 1984-12-18 Elmar Sturm Antimicrobial triazole derivatives

Also Published As

Publication number Publication date
CA1210012A (en) 1986-08-19
JPS5989668A (ja) 1984-05-23
DE3371079D1 (en) 1987-05-27
AU575789B2 (en) 1988-08-11
ZA837599B (en) 1985-05-29
US4489087A (en) 1984-12-18
ES526445A0 (es) 1985-10-01
EP0111384A1 (en) 1984-06-20
NZ205940A (en) 1986-09-10
AU2011583A (en) 1984-04-19
EP0111384B1 (en) 1987-04-22

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