ES8600313A1 - Un procedimiento para la preparacion de una sal de levamisol-acido l-n((4-metoxifenil)sulfonil) glutamico - Google Patents
Un procedimiento para la preparacion de una sal de levamisol-acido l-n((4-metoxifenil)sulfonil) glutamicoInfo
- Publication number
- ES8600313A1 ES8600313A1 ES537555A ES537555A ES8600313A1 ES 8600313 A1 ES8600313 A1 ES 8600313A1 ES 537555 A ES537555 A ES 537555A ES 537555 A ES537555 A ES 537555A ES 8600313 A1 ES8600313 A1 ES 8600313A1
- Authority
- ES
- Spain
- Prior art keywords
- addition salt
- tetramisole
- acid addition
- levamisole
- isolating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 title abstract 4
- 229960001614 levamisole Drugs 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 5
- 238000006243 chemical reaction Methods 0.000 abstract 2
- DETPSUHECVIOBF-JTQLQIEISA-N (2s)-2-[(4-methoxyphenyl)sulfonylamino]pentanedioic acid Chemical compound COC1=CC=C(S(=O)(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 DETPSUHECVIOBF-JTQLQIEISA-N 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838329869A GB8329869D0 (en) | 1983-11-09 | 1983-11-09 | Isolating levamisole from tetramisole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES537555A0 ES537555A0 (es) | 1985-09-16 |
| ES8600313A1 true ES8600313A1 (es) | 1985-09-16 |
Family
ID=10551481
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES537555A Expired ES8600313A1 (es) | 1983-11-09 | 1984-11-08 | Un procedimiento para la preparacion de una sal de levamisol-acido l-n((4-metoxifenil)sulfonil) glutamico |
| ES537554A Expired ES8604978A1 (es) | 1983-11-09 | 1984-11-08 | Un procedimiento para aislar levamisol o una sal de adicion de acido farmaceuticamente aceptable del mismo |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES537554A Expired ES8604978A1 (es) | 1983-11-09 | 1984-11-08 | Un procedimiento para aislar levamisol o una sal de adicion de acido farmaceuticamente aceptable del mismo |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0142191B1 (2) |
| JP (1) | JPS60115591A (2) |
| KR (1) | KR880002236B1 (2) |
| AR (1) | AR240829A1 (2) |
| AT (1) | ATE50996T1 (2) |
| AU (1) | AU566409B2 (2) |
| CA (1) | CA1239408A (2) |
| DE (1) | DE3481617D1 (2) |
| DK (1) | DK532584A (2) |
| ES (2) | ES8600313A1 (2) |
| GB (1) | GB8329869D0 (2) |
| GR (1) | GR80883B (2) |
| IL (1) | IL73449A (2) |
| IN (1) | IN160024B (2) |
| NZ (1) | NZ210015A (2) |
| PT (1) | PT79458B (2) |
| ZA (1) | ZA848747B (2) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010136526A1 (en) * | 2009-05-29 | 2010-12-02 | Janssen Pharmaceutica Nv | Resolution of (±)-methyl phenyl[4-[4-[[[4'-(trifluoromethyl)-2-biphenylyl]carbonyl]amino]phenyl]-1-piperidinyl]acetate |
| CN102675346A (zh) * | 2012-05-28 | 2012-09-19 | 重庆大学 | 一种左旋咪唑有机酸盐,其合成方法和它的药物组合物 |
| CN117800881A (zh) * | 2023-11-22 | 2024-04-02 | 常州齐晖药业有限公司 | 一种盐酸左旋咪唑拆分剂n-对甲苯磺酰-l-(+)-谷氨酸的回收方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU421744B2 (en) * | 1967-08-24 | 1972-02-24 | I. C. I. Australia Limited | Chemical process |
-
1983
- 1983-11-09 GB GB838329869A patent/GB8329869D0/en active Pending
-
1984
- 1984-09-17 IN IN655/CAL/84A patent/IN160024B/en unknown
- 1984-10-15 KR KR1019840006359A patent/KR880002236B1/ko not_active Expired
- 1984-10-15 CA CA000465415A patent/CA1239408A/en not_active Expired
- 1984-10-16 EP EP84201496A patent/EP0142191B1/en not_active Expired - Lifetime
- 1984-10-16 DE DE8484201496T patent/DE3481617D1/de not_active Expired - Lifetime
- 1984-10-16 AT AT84201496T patent/ATE50996T1/de not_active IP Right Cessation
- 1984-10-23 AR AR298343A patent/AR240829A1/es active
- 1984-10-26 NZ NZ210015A patent/NZ210015A/en unknown
- 1984-11-01 JP JP59229059A patent/JPS60115591A/ja active Granted
- 1984-11-06 PT PT79458A patent/PT79458B/pt not_active IP Right Cessation
- 1984-11-07 IL IL73449A patent/IL73449A/xx not_active IP Right Cessation
- 1984-11-08 ES ES537555A patent/ES8600313A1/es not_active Expired
- 1984-11-08 DK DK532584A patent/DK532584A/da not_active Application Discontinuation
- 1984-11-08 GR GR80883A patent/GR80883B/el unknown
- 1984-11-08 AU AU35237/84A patent/AU566409B2/en not_active Expired
- 1984-11-08 ES ES537554A patent/ES8604978A1/es not_active Expired
- 1984-11-08 ZA ZA848747A patent/ZA848747B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR880002236B1 (ko) | 1988-10-20 |
| EP0142191B1 (en) | 1990-03-14 |
| NZ210015A (en) | 1987-04-30 |
| ES537554A0 (es) | 1986-04-01 |
| PT79458A (en) | 1984-12-01 |
| GB8329869D0 (en) | 1983-12-14 |
| ZA848747B (en) | 1986-06-25 |
| AR240829A1 (es) | 1991-02-28 |
| IN160024B (2) | 1987-06-20 |
| IL73449A (en) | 1988-05-31 |
| KR850003895A (ko) | 1985-06-29 |
| AU3523784A (en) | 1985-05-30 |
| ES8604978A1 (es) | 1986-04-01 |
| JPS60115591A (ja) | 1985-06-22 |
| EP0142191A2 (en) | 1985-05-22 |
| GR80883B (en) | 1984-11-29 |
| ATE50996T1 (de) | 1990-03-15 |
| AR240829A2 (es) | 1991-02-28 |
| CA1239408A (en) | 1988-07-19 |
| ES537555A0 (es) | 1985-09-16 |
| DK532584A (da) | 1985-05-10 |
| AU566409B2 (en) | 1987-10-22 |
| IL73449A0 (en) | 1985-02-28 |
| JPH0516435B2 (2) | 1993-03-04 |
| EP0142191A3 (en) | 1986-02-19 |
| DK532584D0 (da) | 1984-11-08 |
| DE3481617D1 (de) | 1990-04-19 |
| PT79458B (en) | 1986-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20050517 |