ES8600498A1 - Un metodo de liofilizar una solucion acuosa de una globulina insoluble en frio - Google Patents

Un metodo de liofilizar una solucion acuosa de una globulina insoluble en frio

Info

Publication number
ES8600498A1
ES8600498A1 ES526254A ES526254A ES8600498A1 ES 8600498 A1 ES8600498 A1 ES 8600498A1 ES 526254 A ES526254 A ES 526254A ES 526254 A ES526254 A ES 526254A ES 8600498 A1 ES8600498 A1 ES 8600498A1
Authority
ES
Spain
Prior art keywords
mannose
weight
globulin
cold insoluble
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526254A
Other languages
English (en)
Other versions
ES526254A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Publication of ES8600498A1 publication Critical patent/ES8600498A1/es
Publication of ES526254A0 publication Critical patent/ES526254A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA LIOFILIZAR UNA SOLUCION ACUOSA DE GLOBULINA INSOLUBLE EN FRIO.CONSISTE EN LIOFILIZAR UNA SOLUCION ACUOSA DE GLOBULINA INSOLUBLE EN FRIO CON UNA CONCENTRACION 0,1 A 10 EN RELACION PESO/VOLUMEN, EN PRESENCIA DE ALBUMINA DE 0,01 A 5 EN RELACION PESO VOLUMEN Y DE UN AGENTE ESTABILIZANTE DE 1 A 10 EN RELACION PESO/VOLUMEN, A UNA TEMPERATURA INICIAL E C30JC Y A UNA PRESION DE 0,001 A 10 MM HG; PARA EVITAR LA TURBIDEZ AL DISOLVER LA GLOBULINA HIOFILIZADA INSOLUBLE EN AGUA. EL AGENTE ESTABILIZANTE SE SELECCIONA ENTRE AMINOACIDOS NEUTROS, COMO GLICINA, ALANINA, VALINA, LEUCINA, MONOSACARIDOS, COMO GLUCOSA, MANNOSA, GALACTOSA O FRUCTOSA, DISACARIDOS, COMO SACAROSA, Y AZUCARES-ALCOHOLES, COMO MANNITA, SORBITA O XILITA.SE UTILIZAN EN FARMACOLOGIA PARA FAVORECER LA CURACION DE HERIDAS DE UN TRAUMA.
ES526254A 1982-10-07 1983-10-05 Un metodo de liofilizar una solucion acuosa de una globulina insoluble en frio Granted ES526254A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57176917A JPS5967228A (ja) 1982-10-07 1982-10-07 寒冷不溶性グロブリンの凍結乾燥方法

Publications (2)

Publication Number Publication Date
ES8600498A1 true ES8600498A1 (es) 1985-10-01
ES526254A0 ES526254A0 (es) 1985-10-01

Family

ID=16022017

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526254A Granted ES526254A0 (es) 1982-10-07 1983-10-05 Un metodo de liofilizar una solucion acuosa de una globulina insoluble en frio

Country Status (5)

Country Link
US (1) US4565651A (es)
EP (1) EP0106608B1 (es)
JP (1) JPS5967228A (es)
DE (1) DE3380924D1 (es)
ES (1) ES526254A0 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2848529A1 (de) * 1978-11-09 1980-05-29 Behringwerke Ag Verfahren zur herstellung des kaelteunloeslichen globulins und dieses enthaltende arzneimittel
ATE31023T1 (de) * 1983-04-28 1987-12-15 Armour Pharma Pharmazeutische zubereitung mit gehalt an gereinigtem fibrinonectin.
JPS61103836A (ja) * 1984-10-24 1986-05-22 Green Cross Corp:The フイブロネクチン製剤
US4743680A (en) * 1985-02-01 1988-05-10 New York University Method for purifying antihemophilic factor
AT385658B (de) * 1985-03-28 1988-05-10 Serotherapeutisches Inst Wien Verfahren zur herstellung einer fuer die anwendung beim menschen geeigneten fibronektinloesung
SE456136B (sv) * 1985-06-17 1988-09-12 Oncholab Ab Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)
US5128119A (en) * 1989-06-12 1992-07-07 Immunomedics, Inc. Methods for technetium/rhenium labeling of f(ab1)2 fragments
CA1340250C (en) * 1989-09-18 1998-12-15 Hans J. Hansen Method for rapidly radiolabeling monovalent antibody fragments with technetium
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
US5564345A (en) * 1993-05-11 1996-10-15 Park Ohio Industries Inc. Stackable table, table assembly, and tray and table combination
JP2948708B2 (ja) * 1991-11-27 1999-09-13 ニューヨーク・ブラッド・センター・インコーポレーテッド フィブロネクチン含有点眼液
US5631225A (en) * 1994-10-13 1997-05-20 Novo Nordisk A/S Pharmaceutical formulation
US5547696A (en) * 1994-10-13 1996-08-20 Novo Nordisk A/S Pharmaceutical formulation
US5654278A (en) * 1994-10-13 1997-08-05 Novo Nordisk A/S Composition and method comprising growth hormone and leucine
IL115592A (en) * 1994-10-13 2000-07-26 Novo Nordisk As Stabilized pharmaceutical formulation comprising a growth hormone and leucine
DE19539574A1 (de) 1995-10-25 1997-04-30 Boehringer Mannheim Gmbh Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren
CN1568999A (zh) * 2003-07-14 2005-01-26 南宁枫叶药业有限公司 稳定的医药用河豚毒素冷冻干燥制剂
MX2007002085A (es) 2004-08-20 2007-07-19 Prometic Biosciences Ltd Esquemas de aislamiento y purificacion consecutivos de proteinas mediante cromatografia de afinidad.
WO2006081320A2 (en) * 2005-01-27 2006-08-03 Human Genome Sciences, Inc. Pharmaceutical formulation
JP4868953B2 (ja) * 2006-06-19 2012-02-01 株式会社前田シェルサービス バレル研磨機における研磨槽のライニング構造の形成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3637640A (en) * 1970-05-04 1972-01-25 Diagnostic Data Inc Orgotein stabilized with saccharide process and products
GB1417003A (en) * 1972-06-22 1975-12-10 Radiochemical Centre Ltd Stabilisation of fibrinogen
CA1064396A (en) * 1975-02-18 1979-10-16 Myer L. Coval Fractional precipitation of gamma globulin with polyethylene glycol
US4027013A (en) * 1976-01-22 1977-05-31 William L. Wilson Clottable fibrinogen free factor VIII and albumin product and process
JPS597693B2 (ja) * 1978-01-07 1984-02-20 株式会社ミドリ十字 抗トロンビン製剤及びその製法
US4315906A (en) * 1979-05-21 1982-02-16 New England Nuclear Corporation Cold insoluble globulin, its purification and use
US4278594A (en) * 1979-06-19 1981-07-14 David Amrani Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
US4341764A (en) * 1980-03-05 1982-07-27 Cutter Laboratories, Inc. Method of preparing fibronectin and antihemophilic factor
JPS56135418A (en) * 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
US4305871A (en) * 1980-09-02 1981-12-15 Edward Shanbrom Method of selectively increasing yield and purity of certain cryoprecipitate proteins by heating
JPS57140724A (en) * 1981-02-25 1982-08-31 Green Cross Corp:The Heat-treatment of aqueous solution containing cold insoluble globulin

Also Published As

Publication number Publication date
EP0106608A2 (en) 1984-04-25
US4565651A (en) 1986-01-21
EP0106608A3 (en) 1986-03-26
JPH0378373B2 (es) 1991-12-13
DE3380924D1 (de) 1990-01-11
ES526254A0 (es) 1985-10-01
EP0106608B1 (en) 1989-12-06
JPS5967228A (ja) 1984-04-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001