ES8601235A1 - Procedimiento para preparar cianoesteroides - Google Patents

Procedimiento para preparar cianoesteroides

Info

Publication number
ES8601235A1
ES8601235A1 ES530204A ES530204A ES8601235A1 ES 8601235 A1 ES8601235 A1 ES 8601235A1 ES 530204 A ES530204 A ES 530204A ES 530204 A ES530204 A ES 530204A ES 8601235 A1 ES8601235 A1 ES 8601235A1
Authority
ES
Spain
Prior art keywords
alkyl
substd
opt
halogen
cyanosteroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530204A
Other languages
English (en)
Other versions
ES530204A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES8601235A1 publication Critical patent/ES8601235A1/es
Publication of ES530204A0 publication Critical patent/ES530204A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE CIANOESTEROIDES DE FORMULA GENERAL (I) EN LA QUE R ES HIDROXI; R1 ES HIDROGENO O ALQUILO CON 1 A 6 ATOMOS DE CARBONO; R2 ES HIDROGENO FENILO HALOGENADO O FENILO; R3 ES HIDROGENO O ALQUILO DE 1 A 6 ATOMOS DE CARBONO; Y X ES -O- O -NH-. CONSISTE EN HACER REACCIONAR UNA MEZCLA DE 2A-CIANO-17B-HIDROXI-4417A-TRIMETILANDROST-5-EN-3-ONA 2-CIANO-17B-HIDROXI-4417A-TRIMETILANDROST-5-EN-3-ONA Y 2-CIANO-17A-TRIMETILANDROSTA-25-DIENO-317B-DIOL CON REACTIVOS ACILANTES A TEMPERATURAS COMPRENDIDAS ENTRE CERO Y 30 GRADOS. DE UTILIDAD PARA INDUCIR LA MENSTRUACION Y LA TERMINACION DEL EMBARAZO EN MAMIFEROS.
ES530204A 1983-03-03 1984-03-01 Procedimiento para preparar cianoesteroides Granted ES530204A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/471,952 US4459235A (en) 1983-03-03 1983-03-03 2-Cyanosteroids

Publications (2)

Publication Number Publication Date
ES8601235A1 true ES8601235A1 (es) 1985-11-01
ES530204A0 ES530204A0 (es) 1985-11-01

Family

ID=23873637

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530204A Granted ES530204A0 (es) 1983-03-03 1984-03-01 Procedimiento para preparar cianoesteroides

Country Status (6)

Country Link
US (1) US4459235A (es)
EP (1) EP0118105A3 (es)
JP (1) JPS59175500A (es)
AU (1) AU2519084A (es)
ES (1) ES530204A0 (es)
ZA (1) ZA841559B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68222A (en) * 1983-03-24 1987-02-27 Yeda Res & Dev Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity
GB8328929D0 (en) * 1983-10-29 1983-11-30 Sterwin Ag Steroid compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3296255A (en) * 1963-11-29 1967-01-03 Sterling Drug Inc 2-cyano steroids
US4160027A (en) * 1977-12-20 1979-07-03 Sterling Drug Inc. Steroid cyanoketones and intermediates
US4349474A (en) * 1981-07-27 1982-09-14 G. D. Searle & Co. 2-Cyanosteroids
US4388311A (en) * 1982-05-06 1983-06-14 G. D. Searle & Co. Method for the induction of menses

Also Published As

Publication number Publication date
AU2519084A (en) 1984-09-06
US4459235A (en) 1984-07-10
EP0118105A2 (en) 1984-09-12
JPS59175500A (ja) 1984-10-04
EP0118105A3 (en) 1985-01-23
ES530204A0 (es) 1985-11-01
ZA841559B (en) 1985-04-24

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