ES8601689A1 - Procedimiento de preparar composiciones farmaceuticas solidas de liberacion sostenida - Google Patents

Procedimiento de preparar composiciones farmaceuticas solidas de liberacion sostenida

Info

Publication number
ES8601689A1
ES8601689A1 ES529858A ES529858A ES8601689A1 ES 8601689 A1 ES8601689 A1 ES 8601689A1 ES 529858 A ES529858 A ES 529858A ES 529858 A ES529858 A ES 529858A ES 8601689 A1 ES8601689 A1 ES 8601689A1
Authority
ES
Spain
Prior art keywords
medium
sustained release
solid pharmaceutical
release solid
compsn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529858A
Other languages
English (en)
Other versions
ES529858A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to ES529858A priority Critical patent/ES529858A0/es
Publication of ES8601689A1 publication Critical patent/ES8601689A1/es
Publication of ES529858A0 publication Critical patent/ES529858A0/es
Granted legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPOSICIONES FARMACEUTICAS SOLIDAS DE LIBERACION PROLONGADA. CONSISTENTES EN MOLER LOS CRISTALES LAMINADOS DEL INGREDIENTE ACTIVO A GRANULOMETRIA INFERIOR A 50 MM, DISPERSAR DEL 2 AL 18% EN PESO, CON RESPECTO A LA CANTIDAD DEL INGREDIENTE ACTIVO, DE UN POLIMERO INSOLUBLE EN AGUA, PREFERENTEMENTE ETILCELULOSA, EN UN MEDIO LIQUIDO, PREFERENTEMENTE CICLOHEXANONA., EN CANTIDAD TAL QUE SE FORME UNA DISOLUCION AL 2-5% EN PESO DEL POLIMERO. COMBINAR EL INGREDIENTE ACTIVO MOLIDO Y LA DISPERSION DEL POLIMERO, CALENTAR LA MEZCLA A POR LO MENOS 80C Y MANTENER ESTA TEMPERATURA DURANTE UNA HORA COMO MINIMO, DEJAR ENFRIAR EL SISTEMA HASTA TEMPERATURA AMBIENTE, RECUPERAR LOS CRISTALES RECUBIERTOS POR FILTRACION, SECARLOS A 25-80C, TAMIZARLOS EN UN TAMIZ DE 0,8 A 1,4 MM, Y COMBINARLOS CON UN AGENTE DESINTEGRADOR CAPAZ DE HINCHARSE EN MEDIO ACUOSO, Y CON OTROS AGENTES AUXILIARES EMPLEADOS EN LA INDUSTRIA FARMACEUTICA. LA MEZCLA SE PRENSA EN FORMA DE TABLETAS.
ES529858A 1984-02-18 1984-02-18 Procedimiento de preparar composiciones farmaceuticas solidas de liberacion sostenida Granted ES529858A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES529858A ES529858A0 (es) 1984-02-18 1984-02-18 Procedimiento de preparar composiciones farmaceuticas solidas de liberacion sostenida

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES529858A ES529858A0 (es) 1984-02-18 1984-02-18 Procedimiento de preparar composiciones farmaceuticas solidas de liberacion sostenida

Publications (2)

Publication Number Publication Date
ES8601689A1 true ES8601689A1 (es) 1985-12-01
ES529858A0 ES529858A0 (es) 1985-12-01

Family

ID=8486903

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529858A Granted ES529858A0 (es) 1984-02-18 1984-02-18 Procedimiento de preparar composiciones farmaceuticas solidas de liberacion sostenida

Country Status (1)

Country Link
ES (1) ES529858A0 (es)

Also Published As

Publication number Publication date
ES529858A0 (es) 1985-12-01

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ES8601689A1 (es) Procedimiento de preparar composiciones farmaceuticas solidas de liberacion sostenida