ES8603383A1 - Un procedimiento para preparar un derivado de amida de acido carboxilico - Google Patents

Un procedimiento para preparar un derivado de amida de acido carboxilico

Info

Publication number
ES8603383A1
ES8603383A1 ES533372A ES533372A ES8603383A1 ES 8603383 A1 ES8603383 A1 ES 8603383A1 ES 533372 A ES533372 A ES 533372A ES 533372 A ES533372 A ES 533372A ES 8603383 A1 ES8603383 A1 ES 8603383A1
Authority
ES
Spain
Prior art keywords
carboxylic acid
derivatives
acid amide
amide compounds
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533372A
Other languages
English (en)
Other versions
ES533372A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES8603383A1 publication Critical patent/ES8603383A1/es
Publication of ES533372A0 publication Critical patent/ES533372A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE AMIDA DE ACIDO CARBOXILICO. CONSISTENTE EN HACER REACCIONAR UNA ANILINA DE FORMULA (II), CON UN ANHIDRIDO CARBOXILICP DE FORMULA (III) PARA OBTENER UN DERIVADO DE AMIDA DE ACIDO CARBOXILICO DE FORMULA (I), EN DONDE X PUEDE SER ATOMO DE HIDROGENO, GRUPO ALQUILO O ALCOXI INFERIOR, HALOGENO O HALOGENURO DE ALQUILO, N ES UN NUMERO ENTERO ENTRE 0 Y 2, Y R1 Y R2 SON ATOMO DE HIDROGENO O GRUPO METILO. APLICACION FARMACOLOGICA CON ACTIVIDAD ANTIESPASMODICA, ANTIHIPOSICA, ANSIOLITICA Y SEDANTE.
ES533372A 1983-06-14 1984-06-13 Un procedimiento para preparar un derivado de amida de acido carboxilico Granted ES533372A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58104873A JPS59231057A (ja) 1983-06-14 1983-06-14 カルボン酸アミド化合物およびその誘導体

Publications (2)

Publication Number Publication Date
ES8603383A1 true ES8603383A1 (es) 1985-12-16
ES533372A0 ES533372A0 (es) 1985-12-16

Family

ID=14392332

Family Applications (2)

Application Number Title Priority Date Filing Date
ES533372A Granted ES533372A0 (es) 1983-06-14 1984-06-13 Un procedimiento para preparar un derivado de amida de acido carboxilico
ES545252A Granted ES545252A0 (es) 1983-06-14 1985-07-16 Un procedimiento para preparar un compuesto de carboximida

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES545252A Granted ES545252A0 (es) 1983-06-14 1985-07-16 Un procedimiento para preparar un compuesto de carboximida

Country Status (17)

Country Link
US (1) US4596826A (es)
JP (1) JPS59231057A (es)
KR (1) KR850001153A (es)
AU (1) AU582117B2 (es)
BE (1) BE899918A (es)
CA (1) CA1215992A (es)
CH (1) CH659243A5 (es)
DE (1) DE3421929A1 (es)
DK (1) DK289684A (es)
ES (2) ES533372A0 (es)
FR (1) FR2548180B1 (es)
GB (1) GB2141713B (es)
HU (1) HU191674B (es)
IT (1) IT1180188B (es)
NL (1) NL8401890A (es)
PH (2) PH20503A (es)
SE (1) SE8403168L (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59118750A (ja) * 1982-12-27 1984-07-09 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体
WO1988006581A1 (fr) * 1987-02-26 1988-09-07 Nippon Zeon Co., Ltd. Derives alicycliques de l'acide dicarboxylique et agents de relaxation musculaire les contenant en tant qu'ingredients actifs
JP4663748B2 (ja) * 2008-03-10 2011-04-06 三菱重工交通機器エンジニアリング株式会社 ボーディングブリッジの接続部およびボーディングブリッジ

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2774787A (en) * 1953-09-03 1956-12-18 Charles F Geschickter Polyhydrophthalamic acid visceral smooth muscle relaxants
US3131509A (en) * 1961-05-08 1964-05-05 Spencer Chem Co Compositions and methods for reducing herbicidal injury
US3507904A (en) * 1966-04-01 1970-04-21 Herbert Schwartz Novel tetrahydrophthalamic acids and derivatives thereof
US3745170A (en) * 1969-03-19 1973-07-10 Sumitomo Chemical Co Novel n-(3,5-dihalophenyl)-imide compounds
US3654302A (en) * 1970-01-30 1972-04-04 Herbert Schwartz Tetrahydrophthalanils
JPS4882038A (es) * 1972-02-08 1973-11-02
US3987056A (en) * 1973-05-07 1976-10-19 Phillips Petroleum Company Disproportionation of n-aryl-1,2,3,6-tetrahydrophthalimides
US4002460A (en) * 1974-03-13 1977-01-11 Stauffer Chemical Company Triazine-antidote compositions and methods of use for cotton
US3996043A (en) * 1975-04-10 1976-12-07 Stauffer Chemical Company Triazine--antidote compositions and methods of use for cotton
PT71116A (de) * 1979-04-20 1980-05-01 Ciba Geigy Ag Verfahren zur herstellung neuer cyclobutandicarbonsaureimide
JPS56169669A (en) * 1980-05-30 1981-12-26 Takeda Chem Ind Ltd Hexahydroisoindole derivative, its preparation and herbicide
JPS59118750A (ja) * 1982-12-27 1984-07-09 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体

Also Published As

Publication number Publication date
GB2141713A (en) 1985-01-03
US4596826A (en) 1986-06-24
HUT36084A (en) 1985-08-28
AU582117B2 (en) 1989-03-16
IT8421378A1 (it) 1985-12-13
HU191674B (en) 1987-03-30
DK289684A (da) 1984-12-15
DK289684D0 (da) 1984-06-13
JPS59231057A (ja) 1984-12-25
FR2548180A1 (fr) 1985-01-04
DE3421929A1 (de) 1984-12-20
FR2548180B1 (fr) 1987-06-12
ES8603824A1 (es) 1986-01-01
PH20503A (en) 1987-01-21
PH21315A (en) 1987-09-28
KR850001153A (ko) 1985-03-16
AU2937984A (en) 1984-12-20
SE8403168L (sv) 1984-12-15
NL8401890A (nl) 1985-01-02
JPH0136820B2 (es) 1989-08-02
IT1180188B (it) 1987-09-23
BE899918A (fr) 1984-12-14
GB2141713B (en) 1987-06-10
SE8403168D0 (sv) 1984-06-13
ES533372A0 (es) 1985-12-16
CH659243A5 (de) 1987-01-15
CA1215992A (en) 1986-12-30
IT8421378A0 (it) 1984-06-13
GB8415153D0 (en) 1984-07-18
ES545252A0 (es) 1986-01-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401