ES8604233A1 - Procedimiento de preparacion de sales sodicas de antibioticos beta-lactamicos - Google Patents
Procedimiento de preparacion de sales sodicas de antibioticos beta-lactamicosInfo
- Publication number
- ES8604233A1 ES8604233A1 ES526971A ES526971A ES8604233A1 ES 8604233 A1 ES8604233 A1 ES 8604233A1 ES 526971 A ES526971 A ES 526971A ES 526971 A ES526971 A ES 526971A ES 8604233 A1 ES8604233 A1 ES 8604233A1
- Authority
- ES
- Spain
- Prior art keywords
- beta
- sodium salts
- group
- biotics
- prepn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003782 beta lactam antibiotic agent Substances 0.000 title abstract 3
- 159000000000 sodium salts Chemical class 0.000 title abstract 3
- 239000002132 β-lactam antibiotic Substances 0.000 title abstract 3
- 229940124586 β-lactam antibiotics Drugs 0.000 title abstract 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- LQSXKWKNDWKEHE-UHFFFAOYSA-N 3-oxobutanamide;sodium Chemical class [Na].CC(=O)CC(N)=O LQSXKWKNDWKEHE-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- WDJHALXBUFZDSR-UHFFFAOYSA-M acetoacetate Chemical compound CC(=O)CC([O-])=O WDJHALXBUFZDSR-UHFFFAOYSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N anhydrous guanidine Natural products NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 150000002357 guanidines Chemical class 0.000 abstract 1
- -1 heterobicyclic amines Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE SALES SODICAS DE ANTIBIOTICOS BETA-LACTAMICOS. CONSISTE EN ADICIONAR UNA AMINA DEL GRUPO DE LAS AMINAS ALIFATICAS CICLICAS, HETEROBICICLICAS O UNA GUANIDINA SUSTITUIDA A LA SUSPENSION DE SU CORRESPONDIENTE FORMA ACIDA EN UNA MEZCLA DE DISOLVENTES CONTENIENDO ISOPROPANOL; Y HACER REACCIONAR LA MEZCLA A TEMPERATURAS COMPRENDIDAS ENTRE 0 Y 30JC CON UN COMPUESTO DEL GRUPO QUE COMPRENDE UN SODIO ACETOACETATO DE ALQUILO O UN SODIO ACETOACETAMIDA N-SUSTITUIDA, SELECCIONADO ENTRE EL GRUPO DE ALQUILOS O SUSTITUYENTES DE BAJO PESO MOLECULAR, PARA OBTENER LAS CORRESPONDIENTES SALES SODICAS DE ANTIBIOTICOS BETA-LACTAMICOS.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES526971A ES8604233A1 (es) | 1983-11-02 | 1983-11-02 | Procedimiento de preparacion de sales sodicas de antibioticos beta-lactamicos |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES526971A ES8604233A1 (es) | 1983-11-02 | 1983-11-02 | Procedimiento de preparacion de sales sodicas de antibioticos beta-lactamicos |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8604233A1 true ES8604233A1 (es) | 1986-02-01 |
| ES526971A0 ES526971A0 (es) | 1986-02-01 |
Family
ID=8486412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526971A Expired ES8604233A1 (es) | 1983-11-02 | 1983-11-02 | Procedimiento de preparacion de sales sodicas de antibioticos beta-lactamicos |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8604233A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115043853A (zh) * | 2022-08-16 | 2022-09-13 | 齐鲁晟华制药有限公司 | 一种头孢氨苄钠的制备方法 |
-
1983
- 1983-11-02 ES ES526971A patent/ES8604233A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES526971A0 (es) | 1986-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20010301 |