ES8604251A1 - Un procedimiento para la preparacion de n-metil-11-aza-10- desoxo-10-dihidroeritromicina a - Google Patents

Un procedimiento para la preparacion de n-metil-11-aza-10- desoxo-10-dihidroeritromicina a

Info

Publication number
ES8604251A1
ES8604251A1 ES544878A ES544878A ES8604251A1 ES 8604251 A1 ES8604251 A1 ES 8604251A1 ES 544878 A ES544878 A ES 544878A ES 544878 A ES544878 A ES 544878A ES 8604251 A1 ES8604251 A1 ES 8604251A1
Authority
ES
Spain
Prior art keywords
formula
give
compound
new
deoxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544878A
Other languages
English (en)
Other versions
ES544878A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/441,981 external-priority patent/US4474768A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8604251A1 publication Critical patent/ES8604251A1/es
Publication of ES544878A0 publication Critical patent/ES544878A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE N-METIL-11-AZA-10-DESOXO-10-DIHIDROERITROMICINA A. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (I), EN LA QUE N VALE 0 O 1, CON HIDROGENO. LA REDUCCION SE LLEVA A CABO CON HIDROGENO A PRESIONES DE 1 A 70 ATMOSFERAS EN UN DISOLVENTE ORGANICO INERTE A LA REACCION, EN PRESENCIA DE UN CATALIZADOR CONSTITUIDO POR UN METAL NOBLE SOBRE UN SOPORTE, O MEDIANTE CATALISIS HOMOGENEA CON EL CATALIZADOR DE WILKINSON, A UNA TEMPERATURA COMPRENDIDA ENTRE 18JC Y 25JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIBACTERIANOS CONTRA MICROORGANISMOS GRAM-POSITIVOS.
ES544878A 1982-11-15 1985-07-04 Un procedimiento para la preparacion de n-metil-11-aza-10- desoxo-10-dihidroeritromicina a Expired ES8604251A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/441,981 US4474768A (en) 1982-07-19 1982-11-15 N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor

Publications (2)

Publication Number Publication Date
ES8604251A1 true ES8604251A1 (es) 1986-01-16
ES544878A0 ES544878A0 (es) 1986-01-16

Family

ID=23755074

Family Applications (3)

Application Number Title Priority Date Filing Date
ES527250A Granted ES527250A0 (es) 1982-11-15 1983-11-14 Un procedimiento para la preparacion del derivado de 11-aza-10-desoxo-10-dihidroeritromicina a
ES544877A Expired ES8604250A1 (es) 1982-11-15 1985-07-04 Un procedimiento para la preparacion del derivado n-metiladode una 11-aza-10-desoxo-10-dihidroeritromicina a
ES544878A Expired ES8604251A1 (es) 1982-11-15 1985-07-04 Un procedimiento para la preparacion de n-metil-11-aza-10- desoxo-10-dihidroeritromicina a

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES527250A Granted ES527250A0 (es) 1982-11-15 1983-11-14 Un procedimiento para la preparacion del derivado de 11-aza-10-desoxo-10-dihidroeritromicina a
ES544877A Expired ES8604250A1 (es) 1982-11-15 1985-07-04 Un procedimiento para la preparacion del derivado n-metiladode una 11-aza-10-desoxo-10-dihidroeritromicina a

Country Status (9)

Country Link
KR (1) KR850000963B1 (es)
CS (1) CS241533B2 (es)
DD (1) DD215787A5 (es)
EG (1) EG16882A (es)
ES (3) ES527250A0 (es)
GR (1) GR77556B (es)
PL (1) PL141924B1 (es)
SU (1) SU1274626A3 (es)
YU (2) YU42885B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
CN110655544A (zh) * 2018-06-28 2020-01-07 洛阳惠中兽药有限公司 一种加米霉素有关物质的分离、制备及纯化方法

Also Published As

Publication number Publication date
YU44519B (en) 1990-08-31
ES8602838A1 (es) 1985-12-01
ES527250A0 (es) 1985-12-01
GR77556B (es) 1984-09-24
ES544877A0 (es) 1986-01-16
YU207583A (en) 1985-12-31
ES544878A0 (es) 1986-01-16
YU133285A (en) 1986-02-28
CS241533B2 (en) 1986-03-13
PL141924B1 (en) 1987-09-30
KR840006671A (ko) 1984-12-01
SU1274626A3 (ru) 1986-11-30
ES8604250A1 (es) 1986-01-16
PL243473A1 (en) 1984-07-30
EG16882A (en) 1989-06-30
CS575883A2 (en) 1985-08-15
YU42885B (en) 1988-12-31
DD215787A5 (de) 1984-11-21
KR850000963B1 (ko) 1985-07-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20051017