ES8604393A1 - Vinpocetine citrate and phosphate - Google Patents
Vinpocetine citrate and phosphateInfo
- Publication number
- ES8604393A1 ES8604393A1 ES530837A ES530837A ES8604393A1 ES 8604393 A1 ES8604393 A1 ES 8604393A1 ES 530837 A ES530837 A ES 530837A ES 530837 A ES530837 A ES 530837A ES 8604393 A1 ES8604393 A1 ES 8604393A1
- Authority
- ES
- Spain
- Prior art keywords
- phosphate
- citrate
- vinpocetine
- treated
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 title abstract 4
- 229910019142 PO4 Inorganic materials 0.000 title abstract 4
- DDNCQMVWWZOMLN-IRLDBZIGSA-N Vinpocetine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(=O)OCC)N5C2=C1 DDNCQMVWWZOMLN-IRLDBZIGSA-N 0.000 title abstract 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title abstract 4
- 239000010452 phosphate Substances 0.000 title abstract 4
- 229960000744 vinpocetine Drugs 0.000 title abstract 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 230000001476 alcoholic effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 abstract 2
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 abstract 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000001508 potassium citrate Substances 0.000 abstract 1
- 229960002635 potassium citrate Drugs 0.000 abstract 1
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 abstract 1
- 235000011082 potassium citrates Nutrition 0.000 abstract 1
- 229910000160 potassium phosphate Inorganic materials 0.000 abstract 1
- 235000011009 potassium phosphates Nutrition 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- 239000001488 sodium phosphate Substances 0.000 abstract 1
- 229910000162 sodium phosphate Inorganic materials 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229960002726 vincamine Drugs 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
Abstract
Vinpocetine citrate and phosphate (I) are new. X = gp. (II) or (III). Vinpocobtained from vincamine by the method given in FR2468605. This is treated in alcoholic or aqueous alcoholic solution with citric acid at 20 deg.C or in aqueous solution with phosphoric acid. - Alternatively, the phosphate or some other salt of vinpocetine may be treated with sodium or potassium citrate, to form (I) citrate, or the citrate, or some other salt of vinpocetine may be treated with sodium or potassium phosphate to form the phosphate.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES530837A ES8604393A1 (en) | 1984-03-21 | 1984-03-21 | Vinpocetine citrate and phosphate |
| DE8484401984T DE3479423D1 (en) | 1984-02-29 | 1984-10-04 | Citrate of vinpocetine, and process for its preparation |
| EP84401984A EP0154756B2 (en) | 1984-02-29 | 1984-10-04 | Citrate of vinpocetine, and process for its preparation |
| JP60037740A JPH0643425B2 (en) | 1984-02-29 | 1985-02-28 | Vinpocetine citrate and drugs containing it |
| US07/006,354 US4749707A (en) | 1984-02-29 | 1987-01-14 | Citric acid salt of (+) vinpocetine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES530837A ES8604393A1 (en) | 1984-03-21 | 1984-03-21 | Vinpocetine citrate and phosphate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES530837A0 ES530837A0 (en) | 1986-02-01 |
| ES8604393A1 true ES8604393A1 (en) | 1986-02-01 |
Family
ID=8487079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES530837A Expired ES8604393A1 (en) | 1984-02-29 | 1984-03-21 | Vinpocetine citrate and phosphate |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8604393A1 (en) |
-
1984
- 1984-03-21 ES ES530837A patent/ES8604393A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES530837A0 (en) | 1986-02-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK235584D0 (en) | PROCEDURE FOR MANUFACTURING A WHEEL PRODUCT | |
| FI860566A0 (en) | FOERFARANDE FOER FRAMSTAELLNING AV SKUMMANDE BLANDNINGAR. | |
| GB2099008B (en) | Enzymatic process for the treatment of xanthan gums to improve the filtrability of their aqueous solutions | |
| DE3261311D1 (en) | Pretreatment composition for phosphatising ferrous metals, and method of preparing the same | |
| ES8604393A1 (en) | Vinpocetine citrate and phosphate | |
| ES8505676A1 (en) | Vinpocetine citrate and phosphate | |
| GB1135354A (en) | Preparation of uricase | |
| FR2564487B1 (en) | AQUEOUS ACID ZINC ELECTROLYTE AND ELECTROLYTIC ZINC DEPOSITION METHOD | |
| ES8206627A1 (en) | Process for manufacturing sweetened liquors and derivatives thereof from cellulose-containing vegetable substrates | |
| PT80912B (en) | PREPARATION PROCESS OF LISERGOL DERIVATIVES | |
| HUT41375A (en) | Process for producing cristalline glutaminic acid, first of all as monosodium salt, and process for producing salts and organic concentrate produced during the process | |
| ES8401308A1 (en) | Shrimp processing | |
| DE3581838D1 (en) | METHOD FOR REDUCING THE SULFURIC ACID CONTENT AND THE CONTENT CONTENT IN WET PROCESS PHOSPHORIC ACID. | |
| ES8608450A1 (en) | Process for the reduction of metal ions in aqueous solutions. | |
| AU7568298A (en) | Purification of polyphosphazene polyacids | |
| GR3001767T3 (en) | Stable aqueous solution of vincristine sulfate | |
| ES8605872A1 (en) | Process for the electrolytic zinc plating of steel | |
| SU565054A1 (en) | Aqueous solution for metals electrochemical pickling | |
| JPS55118364A (en) | Method of desalting and seasoning japanese pickled plum | |
| EP0154950A3 (en) | Tin-plate degreasing detergent | |
| JPS6418492A (en) | Waste liquid treatment method | |
| IT1150756B (en) | PROCEDURE FOR PREPARING 3ALPHA, 7BETA-DIHYDROXY-5BETA-COLANIC ACID | |
| Kiselev et al. | Effect of Phosphoric Acid on Corrosion Behavior of Steel 03 Kh 21 N 21 M 4 GB in Hydrofluorosilicylic Acid Solutions | |
| NZ210496A (en) | Manufacture of concentrated aqueous arsenic acid solution | |
| HUT47651A (en) | Surface treating, passivating pickle composition for iron and steel structural materials |