ES8607008A1 - Procedimiento para la preparar una tableta farmaceutica para procurar una liberacion sostenidad de medicamento. - Google Patents

Procedimiento para la preparar una tableta farmaceutica para procurar una liberacion sostenidad de medicamento.

Info

Publication number
ES8607008A1
ES8607008A1 ES526901A ES526901A ES8607008A1 ES 8607008 A1 ES8607008 A1 ES 8607008A1 ES 526901 A ES526901 A ES 526901A ES 526901 A ES526901 A ES 526901A ES 8607008 A1 ES8607008 A1 ES 8607008A1
Authority
ES
Spain
Prior art keywords
active ingredient
uniform distribution
sustained
medicament
dosage forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526901A
Other languages
English (en)
Other versions
ES526901A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of ES526901A0 publication Critical patent/ES526901A0/es
Publication of ES8607008A1 publication Critical patent/ES8607008A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PERFECCIONAMIENTO EN UN PROCEDIMIENTO PARA PREPARAR UNA TABLETA FARMACEUTICA PARA PROCURAR UNA LIBERACION SOSTENIDA DE MEDICAMENTO. CONSISTENTE EN: CALCULAR LA CANTIDAD DEL MEDICAMENTO QUE DEBE USARSE EN EL NUCLEO O EN CUALQUIER CAPA DE LIBERACION SOSTENIDA, POR LA FORMULA DL F DT D RD/RT, SIENDO DL LA CANTIDAD DE MECICAMENTO EN PORCION DE LIBERACION SOSTENIDA DE LA TABLETA, QUE PUEDE SER DE 0,1 MG A 500 MG; RD ES EL RADIO DIFERENCIAL PARA EL NUCLEO O LA CAPA ENVOLVENTE Y ES DE 0,796 MILIMETROS A 12,70 MILIMETROS; Y RT ES EL RADIO DE LA PORCION DE LIBERACION SOSTENIDA DE LA TABLETA Y ES DE 1,59 MILIMETROS A 12,70 MILIMETROS. CONSISTIENDO EL NUCLEO Y LAS CAPAS ENVOLVENTES DE LIBERACION SOSTENIDA, EN UNA MEZCLA DE MEDICAMENTO, EN UNA CANTIDAD CONSTANTE DE GEL HIDROFILO Y EXCIPIENTES. SIENDO EL MEDICAMENTO, TERBUTALINA, TERFENADINA O HIDROCLORURO, Y EL GEL HIDROFILO ES HIDROXIPROPIL METILCELULOSA DE UNA VISCOSIDAD DE 4.000 CENTIPOISES.
ES526901A 1982-11-01 1983-10-28 Procedimiento para la preparar una tableta farmaceutica para procurar una liberacion sostenidad de medicamento. Expired ES8607008A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43810082A 1982-11-01 1982-11-01
US53612883A 1983-09-27 1983-09-27

Publications (2)

Publication Number Publication Date
ES526901A0 ES526901A0 (es) 1986-06-16
ES8607008A1 true ES8607008A1 (es) 1986-06-16

Family

ID=27031546

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526901A Expired ES8607008A1 (es) 1982-11-01 1983-10-28 Procedimiento para la preparar una tableta farmaceutica para procurar una liberacion sostenidad de medicamento.

Country Status (13)

Country Link
EP (1) EP0111144B1 (es)
KR (1) KR900007311B1 (es)
AU (1) AU554377B2 (es)
CA (1) CA1220137A (es)
DE (1) DE3368011D1 (es)
DK (1) DK499183A (es)
ES (1) ES8607008A1 (es)
GR (1) GR78740B (es)
IE (1) IE56182B1 (es)
IL (1) IL70071A (es)
NO (1) NO163356C (es)
NZ (1) NZ206094A (es)
PH (1) PH20332A (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE33994E (en) * 1983-08-16 1992-07-14 Burroughs Wellcome Co. Pharmaceutical delivery system
US4624848A (en) * 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
US4749576A (en) * 1984-05-10 1988-06-07 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
DE3485618D1 (de) * 1984-08-17 1992-04-30 Wellcome Found Zusammensetzung zur kontrollierten abgabe eines wirkstoffes und ihre herstellung.
EP0297650A1 (en) * 1987-06-26 1989-01-04 Duphar International Research B.V Compositions with controlled zero-order delivery rate and method of preparing these compositions
US5219575A (en) * 1987-06-26 1993-06-15 Duphar International Research B.V. Compositions with controlled zero-order delivery rate and method of preparing these compositions
US4996061A (en) * 1987-10-07 1991-02-26 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol-decongestant combination
CN1053570C (zh) * 1987-10-07 2000-06-21 默尔多药物公司 哌啶子基链烷醇的药用组合物-减充血剂复方的制备方法
US4999226A (en) * 1988-06-01 1991-03-12 Merrell Dow Pharmaceuticals Inc. Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
US5198227A (en) * 1990-01-22 1993-03-30 Mcneil-Ppc, Inc. Dual subcoated simulated capsule medicament
SK279684B6 (sk) * 1993-06-14 1999-02-11 Janssen Pharmaceutica N.V. Tableta a spôsob jej výroby
US5484607A (en) * 1993-10-13 1996-01-16 Horacek; H. Joseph Extended release clonidine formulation
US5451409A (en) * 1993-11-22 1995-09-19 Rencher; William F. Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends
US5393765A (en) * 1993-12-13 1995-02-28 Hoffmann-La Roche Inc. Pharmaceutical compositions with constant erosion volume for zero order controlled release
DE19608423A1 (de) * 1996-03-05 1997-09-11 Merck Patent Gmbh Implantate mit phasenweiser Arzneistoffabgabe
US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
EP0811374A1 (en) 1996-05-29 1997-12-10 Pfizer Inc. Combination dosage form comprising cetirizine and pseudoephedrine
US6197340B1 (en) 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
DE10031043A1 (de) 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
KR100402053B1 (ko) * 2000-09-28 2003-10-17 한국화학연구원 항생제의 서방성 임플란트 제제
WO2003037244A2 (en) * 2001-10-29 2003-05-08 Therics, Inc. System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
WO2008154339A2 (en) 2007-06-08 2008-12-18 Addrenex Pharmaceuticals, Inc. Extended release formulation and method of treating adrenergic dysregulation
PL2826467T3 (pl) 2010-12-22 2018-01-31 Purdue Pharma Lp Zamknięte, zabezpieczone przed manipulowaniem formy dozowania o kontrolowanym uwalnianiu
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US10702548B2 (en) 2015-03-04 2020-07-07 Joelle Michele Forbes Compositions and methods for treating drug addiction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1139869A (en) * 1966-01-06 1969-01-15 Moore Medicinal Products Ltd Improvements in or relating to tablets
US3965255A (en) * 1974-05-01 1976-06-22 E. E. Eljim Ecology Ltd. Controlled drug releasing preparations
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
US4122157A (en) * 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator

Also Published As

Publication number Publication date
IE56182B1 (en) 1991-05-08
ES526901A0 (es) 1986-06-16
KR900007311B1 (ko) 1990-10-08
DE3368011D1 (en) 1987-01-15
IL70071A (en) 1987-12-31
PH20332A (en) 1986-12-02
CA1220137A (en) 1987-04-07
NO163356B (no) 1990-02-05
NO163356C (no) 1990-05-16
EP0111144A1 (en) 1984-06-20
IE832543L (en) 1984-05-01
IL70071A0 (en) 1984-01-31
AU554377B2 (en) 1986-08-21
GR78740B (es) 1984-10-02
NO833961L (no) 1984-05-02
EP0111144B1 (en) 1986-12-03
AU2080383A (en) 1984-05-10
NZ206094A (en) 1986-10-08
DK499183A (da) 1984-05-02
DK499183D0 (da) 1983-10-31
KR840006765A (ko) 1984-12-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519