ES8607286A1 - Procedimiento de obtencion de un derivado de n-pirimidino-2-piperacina y sus sales - Google Patents
Procedimiento de obtencion de un derivado de n-pirimidino-2-piperacina y sus salesInfo
- Publication number
- ES8607286A1 ES8607286A1 ES544446A ES544446A ES8607286A1 ES 8607286 A1 ES8607286 A1 ES 8607286A1 ES 544446 A ES544446 A ES 544446A ES 544446 A ES544446 A ES 544446A ES 8607286 A1 ES8607286 A1 ES 8607286A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrimidino
- piperazine
- prepn
- derivs
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 2
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- YSPSCGBXXQSAFS-UHFFFAOYSA-N 4-(4-pyrimidin-2-ylpiperazin-1-yl)butanenitrile Chemical compound C1CN(CCCC#N)CCN1C1=NC=CC=N1 YSPSCGBXXQSAFS-UHFFFAOYSA-N 0.000 abstract 1
- GFWLMILMVMCJDI-UHFFFAOYSA-N 8-oxaspiro[4.5]decane-7,9-dione Chemical compound C1C(=O)OC(=O)CC11CCCC1 GFWLMILMVMCJDI-UHFFFAOYSA-N 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- OKUDBXZACZBZJE-UHFFFAOYSA-N bis(2-methoxyethoxy)aluminum;sodium Chemical compound [Na].COCCO[Al]OCCOC OKUDBXZACZBZJE-UHFFFAOYSA-N 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE N-PIRIMIDINO-2-PIPERACINA Y DE SUS SALES, DE FORMULA (I), EN LA QUE XH ES UN ACIDO. CONSISTE EN LA REDUCCION DE 4-(2-PIRIMIDINIL)-1-(3-CIANOPROPIL)PIPERACINA CON HIDRURO DE SODIO BIS (2-METOXIETOXI)ALUMINIO, EN UN MEDIO HIDROCARBURO AROMATICO, A UNA TEMPERATURA COMPRENDIDA ENTRE LA AMBIENTE Y LA DE EBULLICION DE LA MEZCLA DE REACCION; SEGUIDA DE LA CONDENSACION DEL PRODUCTO FORMADO CON ANHIDRIDO 3,3-TETRAMETILENGLUTARICO EN TOLUENO, A TEMPERATURA COMPRENDIDA ENTRE 20JC Y 100JC; Y, FINALMENTE, TRATAMIENTO CON UNA CANTIDAD EQUIVALENTE DE ACIDO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO TRANQUILIZANTES.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES544446A ES8607286A1 (es) | 1985-06-21 | 1985-06-21 | Procedimiento de obtencion de un derivado de n-pirimidino-2-piperacina y sus sales |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES544446A ES8607286A1 (es) | 1985-06-21 | 1985-06-21 | Procedimiento de obtencion de un derivado de n-pirimidino-2-piperacina y sus sales |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES544446A0 ES544446A0 (es) | 1986-05-16 |
| ES8607286A1 true ES8607286A1 (es) | 1986-05-16 |
Family
ID=8489399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES544446A Expired ES8607286A1 (es) | 1985-06-21 | 1985-06-21 | Procedimiento de obtencion de un derivado de n-pirimidino-2-piperacina y sus sales |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8607286A1 (es) |
-
1985
- 1985-06-21 ES ES544446A patent/ES8607286A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES544446A0 (es) | 1986-05-16 |
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