ES8700248A3 - Un metodo para preparar una composicion farmaceutica a base de 1,3-bis (2-carboxi-cromon-5-iloxi)-propan-2-ol o una de sus sales. - Google Patents
Un metodo para preparar una composicion farmaceutica a base de 1,3-bis (2-carboxi-cromon-5-iloxi)-propan-2-ol o una de sus sales.Info
- Publication number
- ES8700248A3 ES8700248A3 ES539572A ES539572A ES8700248A3 ES 8700248 A3 ES8700248 A3 ES 8700248A3 ES 539572 A ES539572 A ES 539572A ES 539572 A ES539572 A ES 539572A ES 8700248 A3 ES8700248 A3 ES 8700248A3
- Authority
- ES
- Spain
- Prior art keywords
- solns
- ppm
- eye
- nasal drop
- pref
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003889 eye drop Substances 0.000 title 1
- 239000007923 nasal drop Substances 0.000 title 1
- -1 4-oxo-4H-1-benzopyran-2-yl Chemical group 0.000 abstract 1
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 abstract 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
METODO DE PREPARACION DE COMPOSICIONES FARMACEUTICAS A BASE DE 1,3-BIS (2-CARBOXI-CROMON-5-ILOXI)-PROPAN-2-OL O ALGUNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES, POR EJEMPLO LA SAL DISODICA, EN FORMA DE SOLUCION ACUOSA, TRANSPARENTE Y ESTERIL. COMPRENDE LA DISOLUCION DE LOS INGREDIENTES EN AGUA, PARA PRODUCIR UNA COMPOSICION QUE CONTIENE DE 0,1 A 10% DEL INGREDIENTE ACTIVO, ESTANDO TODOS LOS INGREDIENTES LO MAS EXTENSOS POSIBLE DE IONES METALICOS. CUANDO LA CONCENTRACION DE ESTOS ES MAYOR DE 0,40 PPM SE INCORPORA DE 0,01 A 0,1% EN PESO O VOLUMEN DE UN AGENTE QUELANTE O SECUESTRANTE, FARMACEUTICAMENTE ACEPTABLE, COMO EDTA O ALGUNA DE SUS SALES, Y OPCIONALMENTE INCORPORAR TAMBIEN DE 0,001 A 0,1% DE UN AGENTE CONSERVANTE TAL COMO EL COMPUESTO DE FORMULA (I), EN QUE R ES ALQUILO DE C8H17 HASTA C18H37, O UNA MEZCLA DE ESTOS.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES539572A ES539572A0 (es) | 1985-01-15 | 1985-01-15 | Un metodo para preparar una composicion farmaceutica a base de 1,3-bis (2-carboxi-cromon-5-iloxi)-propan-2-ol o una de sus sales. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES539572A ES539572A0 (es) | 1985-01-15 | 1985-01-15 | Un metodo para preparar una composicion farmaceutica a base de 1,3-bis (2-carboxi-cromon-5-iloxi)-propan-2-ol o una de sus sales. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8700248A3 true ES8700248A3 (es) | 1986-09-16 |
| ES539572A0 ES539572A0 (es) | 1986-09-16 |
Family
ID=8488538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES539572A Granted ES539572A0 (es) | 1985-01-15 | 1985-01-15 | Un metodo para preparar una composicion farmaceutica a base de 1,3-bis (2-carboxi-cromon-5-iloxi)-propan-2-ol o una de sus sales. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES539572A0 (es) |
-
1985
- 1985-01-15 ES ES539572A patent/ES539572A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES539572A0 (es) | 1986-09-16 |
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